Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kent E. Williams"'
Autor:
Bin Qiu, Zhaohui Zhong, Longyu Dou, Yuxue Xu, Yi Zou, Korri Weldon, Jun Wang, Lingling Zhang, Ming Liu, Kent E. Williams, John Paul Spence, Richard L. Bell, Zhao Lai, Weidong Yong, Tiebing Liang
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-25 (2024)
Abstract Background and aims Previously, we found that FK506 binding protein 51 (Fkbp51) knockout (KO) mice resist high fat diet-induced fatty liver and alcohol-induced liver injury. The aim of this research is to identify the mechanism of Fkbp51 in
Externí odkaz:
https://doaj.org/article/3e226da478814dd7a0ba3d0480b1c15d
Autor:
Kent E. Williams, Yi Zou, Bin Qiu, Tatsuyoshi Kono, Changyong Guo, Dawn Garcia, Hanying Chen, Tamara Graves, Zhao Lai, Carmella Evans-Molina, Yao-Ying Ma, Suthat Liangpunsakul, Weidong Yong, Tiebing Liang
Publikováno v:
Cells, Vol 13, Iss 1, p 89 (2023)
High levels of alcohol intake alter brain gene expression and can produce long-lasting effects. FK506-binding protein 51 (FKBP51) encoded by Fkbp5 is a physical and cellular stress response gene and has been associated with alcohol consumption and wi
Externí odkaz:
https://doaj.org/article/bd9ba3e9865a4a2db1ec431a34823b1f
Autor:
Tiebing Liang, Janaiah Kota, Kent E. Williams, Romil Saxena, Samer Gawrieh, Xiaoling Zhong, Teresa A. Zimmers, Naga Chalasani
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14564 (2023)
MicroRNA-29a (miR-29a) is a well characterized fibro-inflammatory molecule and its aberrant expression is linked to a variety of pathological liver conditions. The long-term effects of a high-fat diet (HFD) in combination with different levels of EtO
Externí odkaz:
https://doaj.org/article/5beccac89bf04bf9a09f941c5b4ea189
Autor:
John Paul Spence, Jill L. Reiter, Bin Qiu, Hao Gu, Dawn K. Garcia, Lingling Zhang, Tamara Graves, Kent E. Williams, Paula J. Bice, Yi Zou, Zhao Lai, Weidong Yong, Tiebing Liang
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Humans show sex differences related to alcohol use disorders (AUD). Animal model research has the potential to provide important insight into how sex differences affect alcohol consumption, particularly because female animals frequently drink more th
Externí odkaz:
https://doaj.org/article/a7c38cbd3c80470aab9fb44238b5dff9
Autor:
Bin Qiu, Zhaohui Zhong, Longyu Dou, Yuxue Xu, Yi Zou, Korri Weldon, Jun Wang, Lingling Zhang, Ming Liu, Kent E. Williams, John Paul Spence, Richard L. Bell, Zhao Lai, Weidong Yong, Tiebing Liang
Background & Aims Liver injury is a common feature of most chronic liver diseases. Previously, we found that Fkbp51 knockout (KO) mice resist high fat diet-induced fatty liver and alcohol-induced liver injury. The aim of this research is to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4bffda32eeabfd400a29fd10f58b94a
https://doi.org/10.21203/rs.3.rs-2679397/v1
https://doi.org/10.21203/rs.3.rs-2679397/v1
Autor:
Yuxue Xu, Yao-Ying Ma, Zhaohui Zhong, Shawn Righter, Tiebing Liang, Weidong Yong, Chao Wang, Ran Deng, Kent E. Williams, Jun Wang, Gavriil Tsechpenakis, Bin Qiu
FK506-binding protein 51 (encoded by Fkpb51, also known as Fkbp5) has been associated with stress-related mental illness. To investigate its function, we studied the morphological consequences of Fkbp51 deletion. Artificial Intelligence-assisted morp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f1e3f0517ee36290ee1c02ddebd510
https://doi.org/10.21203/rs.3.rs-493867/v1
https://doi.org/10.21203/rs.3.rs-493867/v1
Autor:
Yuxue Xu, Weinian Shou, Zhongwen Xie, Robert B. Stewart, Weidong Yong, Bin Qiu, Longyu Dou, Ming Liu, Kent E. Williams, Chao Wang, Ran Deng, Wei Ren, Zhenwen Zhao, Tiebing Liang, Jun Wang
Publikováno v:
Neuroscience. 402:23-36
FKBP5 (FKBP51) is a glucocorticoid receptor (GR) binding protein, which acts as a co-chaperone of heat shock protein 90 (HSP90) and negatively regulates GR. Its association with mental disorders has been identified, but its function in disease develo
Autor:
Tiebing Liang, John P. Spence, Sha Cao, Jill L. Reiter, Kent E. Williams, Richard L. Bell, Dongbing Lai
Publikováno v:
Alcohol
Background Paternal alcohol abuse is a well-recognized risk factor for the development of an alcohol use disorder (AUD). In addition to genetic and environmental risk factors, heritable epigenetic factors also have been proposed to play a key role in
Autor:
Yuxue Xu, Jun Wang, Bin Qiu, Kent E. Williams, Weidong Yong, Tingting Wang, Tiebing Liang, Ran Deng, Chao Wang, Lingling Zhang, Ming Liu, Zhiwei Yang
Publikováno v:
Biochemical and Biophysical Research Communications. 485:761-767
FK506-binding protein 51 (FKBP51) is one of the most important regulators in the GR-mediated stress response, and we previously demonstrated that loss of FKBP5 arrests adipogenesis and renders mice resistant to diet-induced obesity (DIO). However, th
Autor:
Tiebing Liang, Sarath Chandra Janga, Raj Vuppalanchi, Vishal Sarasani, Naga Chalasani, Kent E. Williams
Publikováno v:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 15(3)