Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kent C Sasse"'
Autor:
Maria Paz Prada, Arsalan U Syed, Olivia R Buonarati, Gopireddy R Reddy, Matthew A Nystoriak, Debapriya Ghosh, Sergi Simó, Daisuke Sato, Kent C Sasse, Sean M Ward, Luis F Santana, Yang K Xiang, Johannes W Hell, Madeline Nieves-Cintrón, Manuel F Navedo
Publikováno v:
eLife, Vol 8 (2019)
Elevated glucose increases vascular reactivity by promoting L-type CaV1.2 channel (LTCC) activity by protein kinase A (PKA). Yet, how glucose activates PKA is unknown. We hypothesized that a Gs-coupled P2Y receptor is an upstream activator of PKA med
Externí odkaz:
https://doaj.org/article/834ddbe5b2af4b2d9cbfe39b3182cbe7
Autor:
Se Eun Ha, Moon Young Lee, Masaaki Kurahashi, Lai Wei, Brian G Jorgensen, Chanjae Park, Paul J Park, Doug Redelman, Kent C Sasse, Laren S Becker, Kenton M Sanders, Seungil Ro
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182265 (2017)
Platelet-derived growth factor receptor alpha (PDGFRα)+ cells are distributed into distinct morphological groups within the serosal, muscular, and submucosal layers as well as the myenteric and deep muscular plexi. PDGFRα+ cells directly interact w
Externí odkaz:
https://doaj.org/article/50deaf005e3a4a19b5839b7d8a35b6d4
Autor:
Maria Paz Prada, Arsalan U. Syed, Gopireddy R. Reddy, Miguel Martín-Aragón Baudel, Víctor A. Flores-Tamez, Kent C. Sasse, Sean M. Ward, Padmini Sirish, Nipavan Chiamvimonvat, Peter Bartels, Eamonn J. Dickson, Johannes W. Hell, John D. Scott, Luis F. Santana, Yang K. Xiang, Manuel F. Navedo, Madeline Nieves-Cintrón
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Molecular mechanisms by which glucose modulates L-type Ca2+ channel activity and vascular reactivity are unclear. Here the authors report a nanocomplex orchestrated by AKAP5 that facilitates local purinergic stimulation of L-type Ca2+ channels and va
Externí odkaz:
https://doaj.org/article/16c1bd62635d42608c4af12cd7cb45a7
Publikováno v:
American Journal of Physiology-Cell Physiology. 324:C992-C1006
The main function of the stomach is to digest ingested food. Gastric antrum muscular contractions mix ingested food with digestive enzymes and stomach acid and propel the chyme through the pyloric sphincter at a rate in which the small intestine can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c649ea3cd44460e53466a5201f1985d1
https://doi.org/10.1152/ajpcell.00043.2023
https://doi.org/10.1152/ajpcell.00043.2023
Autor:
Miguel, Martín-Aragón Baudel, Victor A, Flores-Tamez, Junyoung, Hong, Gopyreddy R, Reddy, Pauline, Maillard, Abby E, Burns, Kwun Nok Mimi, Man, Kent C, Sasse, Sean M, Ward, William A, Catterall, Donald M, Bers, Johannes W, Hell, Madeline, Nieves-Cintrón, Manuel F, Navedo
Publikováno v:
Circulation research. 131(12)
L-type CaA multiscale approach including patch-clamp electrophysiology, super-resolution nanoscopy, proximity ligation assay, calcium imaging' pressure myography, and Laser Speckle imaging was implemented to examine CaCaThese results suggest that PKA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0c6325b19db203878c57a32ce5c5a4e
https://pubmed.ncbi.nlm.nih.gov/36345826
https://pubmed.ncbi.nlm.nih.gov/36345826
Autor:
Terry L. Powley, Billie Hunne, Deborah Jaffey, Linda J Fothergill, Kent C. Sasse, Martin J. Stebbing, John B. Furness, Lalita Oparija-Rogenmozere, Sean M. Ward, Madeleine Di Natale
Publikováno v:
Cell Tissue Res
The stomach acts as a buffer between the ingestion of food and its processing in the small intestine. It signals to the brain to modulate food intake and it in turn regulates the passage of a nutrient-rich fluid, containing partly digested food, into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405e113308d5eea5b3ef378247889ccf
https://doi.org/10.1007/s00441-020-03294-7
https://doi.org/10.1007/s00441-020-03294-7
Autor:
Miguel Martín-Aragón Baudel, Peter Bartels, Madeline Nieves-Cintrón, Víctor A. Flores-Tamez, Kent C. Sasse, Nipavan Chiamvimonvat, Johannes W. Hell, G. R. Reddy, John D. Scott, Luis Fernando Santana, Arsalan U. Syed, Eamonn J. Dickson, Maria Paz Prada, Sean M. Ward, Padmini Sirish, Yang Kevin Xiang, Manuel F. Navedo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
The L-type Ca2+ channel CaV1.2 is essential for arterial myocyte excitability, gene expression and contraction. Elevations in extracellular glucose (hyperglycemia) potentiate vascular L-type Ca2+ channel via PKA, but the underlying mechanisms are unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82eb0ff076a26f37a5821e35c2f5b808
http://link.springer.com/article/10.1038/s41467-020-18947-y
http://link.springer.com/article/10.1038/s41467-020-18947-y
Autor:
Kent C. Sasse, Rachael Lambin, Jonathan Gevorkian, Deacon Shoenberger, John-Henry Lambin, Andrew Ahrendt, Makayla Cox, Emerson M. Epstein, Austin Shinagawa
Publikováno v:
Obesity Surgery. 30:4258-4266
Previous research demonstrates that exposure to adverse childhood experiences (ACEs) is associated with development of obesity. The same mechanisms mediating this relationship could theoretically affect attempts to lose weight in adulthood. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7daec679012fd6e2dc6ba299b3a43a5
https://doi.org/10.1007/s11695-020-04779-8
https://doi.org/10.1007/s11695-020-04779-8
Autor:
Se Eun, Ha, Brian G, Jorgensen, Lai, Wei, Byungchang, Jin, Min-Seob, Kim, Sandra M, Poudrier, Rajan, Singh, Allison, Bartlett, Hannah, Zogg, Sei, Kim, Gain, Baek, Masaaki, Kurahashi, Moon-Young, Lee, Yong-Sung, Kim, Suck-Chei, Choi, Kent C, Sasse, Samuel J S, Rubin, Andres, Gottfried-Blackmore, Laren, Becker, Aida, Habtezion, Kenton M, Sanders, Seungil, Ro
Publikováno v:
International journal of molecular sciences. 23(9)
Metalloendopeptidase ADAM-Like Decysin 1 (ADAMDEC1) is an anti-inflammatory peptidase that is almost exclusively expressed in the gastrointestinal (GI) tract. We have recently found abundant and selective expression of Adamdec1 in colonic mucosal PDG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8595438da34ed0c056d68b0a647d5eee
https://pubmed.ncbi.nlm.nih.gov/35563399
https://pubmed.ncbi.nlm.nih.gov/35563399
Autor:
Victor Flores, Madeline Cintron, Raghavender Reddy Gopireddy, Sean M. Ward, Manuel F. Navedo, Yang Xiang, Manuela Zaccolo, Kent C. Sasse
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d8e0cab34d38255345bcee52a6f0d84
https://doi.org/10.1096/fasebj.2021.35.s1.02419
https://doi.org/10.1096/fasebj.2021.35.s1.02419