Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Kent A. Kirchner"'
Publikováno v:
The American Journal of the Medical Sciences. 322:145-150
The allocation of medical resources is often a great concern in the United States. This article discusses a case concerning utility of resources in a patient with a terminal disease. We assert that the goals of treatment tailored to an individual pat
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 24:600-606
SUMMARY 1. According to the renal body fluid feedback mechanism for long-term control, persistent hypertension can only occur as a result of a reduction in renal sodium excretory function or a hypertensive shift in the pressure natriuresis relationsh
Publikováno v:
Hypertension. 27:668-671
Abstract Although it has been reported that Na + ,K + -ATPase inhibition with bufalin induces acute and chronic hypertension in the rat, the mechanisms mediating this response are unclear. To examine the role of the kidney in this process, glomerular
Publikováno v:
Hypertension. 25:883-887
Abstract Hypertension in the spontaneously hypertensive rat (SHR) is associated with reduced renal excretory function, low renal plasma flow, reduced glomerular filtration rate, and reduced renal interstitial hydrostatic pressure. The mechanisms resp
Autor:
Jerome D. Cohen, Nemat O. Borhani, William B. Applegate, Charles H. Hennekens, Edward Lakatos, Frank M. Sacks, Kent A. Kirchner, James Taylor, Monica E. Yamamoto, Michael J. Klag
Publikováno v:
Annals of Epidemiology. 5:96-107
Phase I of the Trials of Hypertension Prevention (TOHP) was a randomized, multicenter investigation that included double-blind, placebo-controlled testing of calcium and magnesium supplementation among 698 healthy adults (10.5% blacks and 31% women)
Autor:
N O Borhani, Victor J. Stevens, Lawrence J. Appel, Jerome D. Cohen, Kent A. Kirchner, Eva Obarzanek, M Yamamoto, Patricia R. Hebert, Julie E. Buring
Publikováno v:
Annals of Epidemiology. 5:149-155
Phase II of the Trials of Hypertension Prevention (TOHP II) is a multicenter, controlled clinical trial designed to test whether weight loss, a reduced sodium intake, or a combination of weight loss and a reduced sodium intake will lower blood pressu
Autor:
Kent A. Kirchner, M. Donald Blaufox, Albert Oberman, Barry R. Davis, Sylvia Wassertheil-Smoller
Publikováno v:
American Journal of Human Biology. 7:195-201
TAIM, the Trial of Antihypertensive Interventions and Management, studied the effects of dietary sodium restriction or weight reduction, alone and in combination with low-dose diuretic or beta blocker on blood pressure after 6 months. The responses t
Publikováno v:
Hypertension. 22:863-869
A blunted pressure-natriuretic response characterizes hypertension in the Dahl salt-sensitive rat. Long-term L-arginine administration prevents hypertension in these animals. To determine if long-term L-arginine corrects the pressure-natriuretic resp
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 262:R1145-R1148
To determine whether calcium entry is necessary for insulin antinatriuresis, urinary sodium excretion was determined before and during euglycemic insulin administration in rats receiving verapamil (10 micrograms.kg-1.min-1) or vehicle. In vehicle rat
Autor:
Kent A. Kirchner
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 262:R263-R268
When studied at equivalent renal perfusion pressures, loop segment chloride reabsorption is greater in hypertensive Dahl salt-sensitive (S) than Dahl salt-resistant (R) rats. To determine whether this difference in loop reabsorption is present before