Zobrazeno 1 - 10
of 4 309
pro vyhledávání: '"Kent, W. A."'
Autor:
Dag Rune Stormoen, Signe Lehn, Kent W. Mouw, Zoltan Szallasi, Linea Cecilie Melchior, Line Hammer Dohn, Judit Börcsok, Maria Rossing, Birgitte Grønkaer Toft, Helle Pappot
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Background Metastatic urothelial carcinoma (mUC) has a poor prognosis, despite recent therapeutic advancements. Prostaglandin Reductase 1 (PTGR1) is essential for activating acylfulvens, a promising class of drugs for treating a subset of ur
Externí odkaz:
https://doaj.org/article/cbe03a455d9d4cd08c3d82aaa8d9d930
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Breast cancer is the most frequently diagnosed cancer worldwide, constituting 15% of cases in 2023. The predominant cause of breast cancer-related mortality is metastasis, and a lack of metastasis-targeted therapies perpetuates dismal outcom
Externí odkaz:
https://doaj.org/article/aa03e11f096f45bca2a6989e6e53387a
Autor:
Benti Geleta Buli, Susanna Lehtinen-Jacks, Peter Larm, Kent W. Nilsson, Charlotta Hellström-Olsson, Fabrizia Giannotta
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Adolescent mental health problems are on the rise globally, including in Sweden. One indicator of this trend is increased psychosomatic symptoms (PSS) over time. Lifestyle factors such as physical activity (PA), diet, smoking, and
Externí odkaz:
https://doaj.org/article/cd3e8566310d44029ce1cb9689dc5e2e
Autor:
Megha Bendre, David Checknita, Aniruddha Todkar, Cecilia Åslund, Sheilagh Hodgins, Kent W. Nilsson
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionRisk-allele carriers of a Monoamine oxidase A (MAOA) gene, short-allele (MAOA-S) in males and long-allele (MAOA-L) in females, in the presence of a negative environment, are associated with alcohol misuse. Whether MAOA-S/L alleles also pr
Externí odkaz:
https://doaj.org/article/6104af132e8c43eebd5691ab9c3ae1f9
Autor:
Lorenz, William R., Holland, Alexis M., Kerr, Samantha W., Mead, Brittany S., Scarola, Gregory T., Kercher, Kent W., Augenstein, Vedra A., Heniford, B. Todd
Publikováno v:
In The American Journal of Surgery December 2024 238
Autor:
Salvino, Matthew J., Ayuso, Sullivan A., Lorenz, William R., Holland, Alexis M., Kercher, Kent W., Augenstein, Vedra A., Heniford, B. Todd
Publikováno v:
In The American Journal of Surgery August 2024 234:136-142
Autor:
Megan R Majocha, Devin E Jackson, Ngoc-Han Ha, Ruhul Amin, Marie Pangrácová, Christina R Ross, Howard H Yang, Maxwell P Lee, Kent W Hunter
Publikováno v:
PLoS Genetics, Vol 20, Iss 5, p e1011236 (2024)
Patients with ER-negative breast cancer have the worst prognosis of all breast cancer subtypes, often experiencing rapid recurrence or progression to metastatic disease shortly after diagnosis. Given that metastasis is the primary cause of mortality
Externí odkaz:
https://doaj.org/article/6290cedd334c4525803ae30e670a3c1c
Autor:
Kent W Jorgenson, Jamie E Hibbert, Ramy KA Sayed, Anthony N Lange, Joshua S Godwin, Paulo HC Mesquita, Bradley A Ruple, Mason C McIntosh, Andreas N Kavazis, Michael D Roberts, Troy A Hornberger
Publikováno v:
eLife, Vol 12 (2024)
An increase in mechanical loading, such as that which occurs during resistance exercise, induces radial growth of muscle fibers (i.e. an increase in cross-sectional area). Muscle fibers are largely composed of myofibrils, but whether radial growth is
Externí odkaz:
https://doaj.org/article/4dced3afb22343c3a3c679665fb37639
Autor:
Mohamed S. Mohamed, Gull Rukh, Sofia Vadlin, Susanne Olofsdotter, Cecilia Åslund, Helgi B. Schiöth, Kent W. Nilsson
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionThe COVID-19 pandemic led to a surge in mental health issues and psychological distress, disruption to work/studying conditions, and social isolation particularly among young adults. Changes in these factors are differentially associated
Externí odkaz:
https://doaj.org/article/122e379fddcb401db7e4a9443e95a2b2
Autor:
Aurel Prosz, Haohui Duan, Viktoria Tisza, Pranshu Sahgal, Sabine Topka, Gregory T. Klus, Judit Börcsök, Zsofia Sztupinszki, Timothy Hanlon, Miklos Diossy, Laura Vizkeleti, Dag Rune Stormoen, Istvan Csabai, Helle Pappot, Joseph Vijai, Kenneth Offit, Thomas Ried, Nilay Sethi, Kent W. Mouw, Sandor Spisak, Shailja Pathania, Zoltan Szallasi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Due to a demonstrated lack of DNA repair deficiencies, clear cell renal cell carcinoma (ccRCC) has not benefitted from targeted synthetic lethality-based therapies. We investigated whether nucleotide excision repair (NER) deficiency is prese
Externí odkaz:
https://doaj.org/article/939969bbc4324201be410156a45cd9e5