Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Kent, Riemondy"'
Autor:
Andrea M. Griesinger, Kent Riemondy, Nithyashri Eswaran, Andrew M. Donson, Nicholas Willard, Eric W. Prince, Simon M.L. Paine, Georgia Bowes, John Rheaume, Rebecca J. Chapman, Judith Ramage, Andrew Jackson, Richard G. Grundy, Nicholas K. Foreman, Timothy A. Ritzmann
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107585- (2023)
Summary: Ependymoma (EPN) is a devastating childhood brain tumor. Single-cell analyses have illustrated the cellular heterogeneity of EPN tumors, identifying multiple neoplastic cell states including a mesenchymal-differentiated subpopulation which c
Externí odkaz:
https://doaj.org/article/c21cc25b1c034ef5b5f324e282f7169c
Autor:
Natalia F. Smirnova, Kent Riemondy, Marta Bueno, Susan Collins, Pavan Suresh, Xingan Wang, Kapil N. Patel, Carlyne Cool, Melanie Königshoff, Nirmal S. Sharma, Oliver Eickelberg
Publikováno v:
JCI Insight, Vol 7, Iss 18 (2022)
Bronchiolitis obliterans syndrome (BOS) is the main reason for poor outcomes after lung transplantation (LTx). We and others have recently identified B cells as major contributors to BOS after LTx. The extent of B cell heterogeneity and the relative
Externí odkaz:
https://doaj.org/article/96c9037e12a14bf89a9c5ed4e05661c0
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
XPO5 mediates nuclear export of miRNA hairpin precursors (pre-miRNAs) through a RanGTP-dependent binding. Here the authors employ HITS-CLIP and biochemical analysis and show that XPO5 binds and promotes nuclear processing of clustered pri-miRNAs, wit
Externí odkaz:
https://doaj.org/article/e5599e5636e1449f8fedcdac30d97247
Autor:
Weiwei Yang, G. Devon Trahan, Elizabeth D. Howell, Nancy A. Speck, Kenneth L. Jones, Austin E. Gillen, Kent Riemondy, Jay Hesselberth, David Bryder, Patricia Ernst
Publikováno v:
Stem Cell Reports, Vol 14, Iss 2, Pp 285-299 (2020)
Summary: The Mixed Lineage Leukemia (MLL1, KMT2A) gene is critical for development and maintenance of hematopoietic stem cells (HSCs), however, whether this protein is limiting for HSC development is unknown due to lack of physiologic model systems.
Externí odkaz:
https://doaj.org/article/c35d9c3f1bf54f7e9b5d1d519b33cb62
Publikováno v:
RNA. 29:596-608
The maternal-to-zygotic transition (MZT) is a conserved embryonic process in animals where developmental control shifts from the maternal to zygotic genome. A key step in this transition is zygotic transcription, and deciphering the MZT requires clas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4385d9ad12c7383afdf507ac07f670
https://doi.org/10.1261/rna.079168.122
https://doi.org/10.1261/rna.079168.122
Autor:
Kathryn D. Tuttle, S. Harsha Krovi, Jingjing Zhang, Romain Bedel, Laura Harmacek, Lisa K. Peterson, Leonard L. Dragone, Adam Lefferts, Catherine Halluszczak, Kent Riemondy, Jay R. Hesselberth, Anjana Rao, Brian P. O’Connor, Philippa Marrack, James Scott-Browne, Laurent Gapin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Invariant natural killer T (iNKT) cells can be subsetted by their cytokine profiles, but how they develop in the thymus is unclear. Here the authors show, by analysing mice carrying mutant Zap70 genes, that T cell receptor signaling strength induces
Externí odkaz:
https://doaj.org/article/9d629b4edd534fecb283ec7b354fbbc7
Autor:
Katherine E. Santostefano, Fiona M. Docherty, Shane P.M. Williams, JaeAnn M. Dwulet, Maria S. Hansen, Richard K.P. Benninger, Kent Riemondy, Holger A. Russ, Ali H. Shilleh, Roberto Castro-Gutierrez, Taylor M. Triolo, Mark A. Wallet, Lucas H. Armitage, Clayton E. Mathews
Publikováno v:
Diabetes
Stem cell–derived β-like cells (sBC) carry the promise of providing an abundant source of insulin-producing cells for use in cell replacement therapy for patients with diabetes, potentially allowing widespread implementation of a practical cure. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed58ff46388f413c2aeedd1b0851524
https://doi.org/10.2337/db20-0873
https://doi.org/10.2337/db20-0873
Autor:
Rui Fu, Neelanjan Mukherjee, William E. Rainey, Amber Baldwin, Kathryn Walters, Kimberly Wellman, Juilee Rege, Kent Riemondy, Antje Hirsekorn
Publikováno v:
RNA
Angiotensin II (AngII) binds to the type I angiotensin receptor in the adrenal cortex to initiate a cascade of events leading to the production of aldosterone, a master regulator of blood pressure. Despite extensive characterization of the transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4551de19cfc89fc6e2e55f28ec8c94d1
https://doi.org/10.1261/rna.078727.121
https://doi.org/10.1261/rna.078727.121
Autor:
Harry A Smith, Elysia Min, Kent Riemondy, Max A. Seibold, Brian J. Day, Katrina W. Kopf, Reena Berman, Jie Huang, Gregory P. Downey, Cecile S. Rose, Hong Wei Chu
Publikováno v:
Toxicol Sci
Upon returning from deployment to Afghanistan, a substantial number of U.S. military personnel report deployment-related lung disease (DRLD) symptoms, including those consistent with an asthma-like airways disease. DRLD is thought to be caused by pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1756dbebe0541f1956f08b65412d4772
https://doi.org/10.1093/toxsci/kfab065
https://doi.org/10.1093/toxsci/kfab065
Autor:
Senthil Lakshmana Chetty, Kent Riemondy, Andrew Donson, Ilango Balaakrishnan, Sujatha Venkataraman, Rajeev Vibhakar, Nicholas Foreman, Siddhartha Mitra
Publikováno v:
Neuro-Oncology. 24:vii131-vii132
Pediatric diffuse midline gliomas (DMGs), are fatal brain tumors of childhood arising in the ventral pons. Currently, radiation therapy (RT) is the mainstay treatment for DIPG. However, RT is not a curative treatment and provides only temporary relie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5255aa8f3386b7e90afd92a4706a2c4c
https://doi.org/10.1093/neuonc/noac209.502
https://doi.org/10.1093/neuonc/noac209.502