Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kensuke Utsunomiya"'
Autor:
Hiroo Sekiya, Fumito Mori, Masaki Nakagawa, Kensuke Utsunomiya, Akira Keida, Yoji Yabe, Hisa-Aki Tanaka
Publikováno v:
IEEE Transactions on Circuits and Systems I: Regular Papers. 67:1762-1774
We propose a method for designing optimal external forcings of injection-locked oscillators. This method enables to maximize the locking range of general injection-locked oscillators under certain practical constraints that encompass the power, magni
Publikováno v:
NeuroMolecular Medicine. 16:398-404
Polydipsia is a serious condition often seen among patients with schizophrenia (SCZ). The cause of polydipsia is unknown; hence, it is hard to treat or manage. Animal studies showed that the drinking behavior is regulated by central dopaminergic neur
Autor:
Yuko Fukunaka, Hung-Yi Chuang, Jun Nakamura, Kenji Yamada, Rudi Hwang, Shinichi Sakata, Takahiro Shinkai, Hsin-I Chen, Kensuke Utsunomiya, Osamu Ohmori, V. De Luca, J.L. Kennedy
Publikováno v:
Pharmacopsychiatry. 46:77-82
INTRODUCTION Smoking is a leading global cause of avoidable mortality. It has been reported that the nicotinic acetylcholine receptor (CHRNA4 and CHRNB2) genes might be associated with smoking behavior in several ethnic populations. However, no study
Autor:
Jun Nakamura, Rudi Hwang, Kenji Yamada, Takahiro Shinkai, Hsin-I Chen, Vincenzo De Luca, Shinichi Sakata, Osamu Ohmori, Kensuke Utsunomiya
Publikováno v:
Neuroscience Letters. 507:52-56
The dopamine D3 receptor gene (DRD3) is considered being one of the candidate genes contributing to the development of tardive dyskinesia (TD). In a recent meta-analysis with mixed ethnicities, only a barely positive association was found between the
Autor:
Wakana Yamaguchi, Rudi Hwang, Osamu Ohmori, Takahiro Shinkai, Yoshiaki Inoue, Yuko Fukunaka, Hsin-I Chen, Kenji Yamada, Jun Nakamura, Shinichi Sakata, Kensuke Utsunomiya
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 33:499-502
Several lines of studies have shown the existence of an important inhibitory mechanism for the control of water intake involving adrenergic alpha2A receptors (ADRA2A). A human study using patients with schizophrenia demonstrated an exacerbation of po
Autor:
Koji Kajiwara, Futoshi Izumi, Susumu Ueno, Eiichi Tachikawa, Tat Beng Cheah, Kensuke Utsunomiya, Nobuyuki Yanagihara, Yumiko Toyohira
Publikováno v:
Journal of Neurochemistry. 76:926-934
Recently, we characterized leptin receptors in bovine adrenal medullary cells (Yanagihara et al. 2000). Here we report the stimulatory effect of leptin on catecholamine synthesis in the cells. Incubating cells with leptin (10 nm) for 20 min increased
Autor:
Shinichi Sakata, Takahiro Shinkai, Vincenzo De Luca, Osamu Ohmori, Kensuke Utsunomiya, Yuko Fukunaka, Jun Nakamura, Yoshiaki Inoue, James L. Kennedy, Rudi Hwang
Publikováno v:
NeuroMolecular Medicine. 10:362-367
P-glycoprotein (P-gp), which is coded by the MDR1 gene, in the brain capillary endothelial cell limits the entry of many drugs including antipsychotics into the brain. The aim of this study is to examine whether a functional polymorphism, a C to T su
Autor:
Osamu Ohmori, Kazuko Shimizu, Shinichi Sakata, Yuko Fukunaka, Takahiro Shinkai, Rudi Hwang, Kensuke Utsunomiya, Chima Matsumoto, Yui Naoe, Hiroko Hori, Jun Nakamura
Publikováno v:
NeuroMolecular Medicine. 9:292-297
The underlying pathophysiology of primary polydipsia in schizophrenia (SCZ) is poorly understood. Our previous study, however, suggested that this condition may have a genetic component [Shinkai et al 2003 Am J Med Genet 119B 7-12]. Orexins, also cal
Autor:
Kohtaro Asayama, Kensuke Utsunomiya, Kazumi Tanaka, Naoya Morisada, Yumiko Toyohira, Yasusada Kawada, Nobuyuki Yanagihara, Susumu Ueno, Masato Tsutsui, Akira Shirahata
Publikováno v:
Biochemical Pharmacology. 66:141-147
Orexin-A has recently been identified as a new hypothalamic peptide working as a mediator in the regulation of feeding behavior and sleep control. To determine the role of orexin-A in peripheral metabolic processes, we examined direct effects of orex
Autor:
Susumu Ueno, Nobuyuki Yanagihara, Masato Tsutsui, Yumiko Toyohira, Tat Beng Cheah, Kensuke Utsunomiya, Yoichi Ueta, Izumi Shibuya, Futoshi Izumi
Publikováno v:
Annals of the New York Academy of Sciences. 971:522-527
Obesity is often associated with cardiovascular and metabolic disorders such as hypertension and hyperglycemia. Leptin, a protein product of the obese gene, regulates satiety and energy expenditure through its receptors in the hypothalamus. Recent st