Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kensuke Satomoto"'
Publikováno v:
Genes and Environment, Vol 46, Iss 1, Pp 1-7 (2024)
Abstract Background Di(2-ethylhexyl) phthalate (DEHP) is a plasticizer commonly used in a wide variety of products, including medical devices. It is rapidly metabolized in the liver into various metabolites upon absorption through oral ingestion, der
Externí odkaz:
https://doaj.org/article/ab00754d305443eca6bee266ad4bf942
Autor:
Kensuke Satomoto, Isamu Suzuki, Koji Mita, Atsushi Wakita, Hiroshi Yamagata, Tatsuya Mitsumoto, Shuichi Hamada
Publikováno v:
Genes and Environment, Vol 44, Iss 1, Pp 1-7 (2022)
Abstract Background The repeated-dose liver micronucleus (RDLMN) assay has been well-developed and applied because of its simplicity and the ease of integration into general toxicity studies which is the preferred method from the 3R’s point of view
Externí odkaz:
https://doaj.org/article/e6673651f7634250afa629763e88b950
Autor:
Shuichi Hamada, Miyuki Shigano, Yumi Wako, Kazufumi Kawasako, Kensuke Satomoto, Tatsuya Mitsumoto, Takayuki Fukuda, Wakako Ohyama, Takeshi Morita, Makoto Hayashi
Publikováno v:
Genes and Environment, Vol 44, Iss 1, Pp 1-9 (2022)
Abstract Background Currently, revisions to the ICH S1 guidance on rodent carcinogenicity testing are being proposed. Application of this approach would reduce the use of animals in accordance with the 3Rs principles (reduce/refine/replace). The meth
Externí odkaz:
https://doaj.org/article/dcffae53b6f441a4900b515615998fe7
Autor:
Masamitsu Moriwaki, Kento Kito, Ryo Nakagawa, Mahendra P Kapoor, Yoshiki Matsumiya, Tomohisa Fukuhara, Junya Kobayashi, Kensuke Satomoto, Hiroshi Yamagata, Yuichi Kuroiwa
Publikováno v:
Bioscience, Biotechnology, and Biochemistry.
Diosmin (DSN) is found mainly in citrus fruits, and has potent antioxidant effects. This study aimed to evaluate pharmacokinetics of diosmetin-7-glucoside-γ-cyclodextrin (DIOSG-CD) inclusion complex. The area under the curve values from AUC0-24 of D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36ef6bcb35c304323690b0cfc044cd8c
https://doi.org/10.1093/bbb/zbad051
https://doi.org/10.1093/bbb/zbad051
Publikováno v:
The Journal of toxicological sciences. 47(6)
Flavonoids such as quercetin and its glucosides, especially isoquercitrin are well known as anti-inflammatory, anti-allergic, and anti-carcinogenic, etc. The safety of isoquercitrin formulations needs to be established prior to their use in functiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2798fde8a17a3d11eefdb7654d110e
https://pubmed.ncbi.nlm.nih.gov/35650139
https://pubmed.ncbi.nlm.nih.gov/35650139
Autor:
Masamitsu Moriwaki, Etsuko Tominaga, Kento Kito, Ryo Nakagawa, Mahendra P. Kapoor, Yoshiki Matsumiya, Tomohisa Fukuhara, Junya Kobayashi, Kensuke Satomoto, Hiroshi Yamagata, Yuichi Kuroiwa
Publikováno v:
Natural Product Communications. 18:1934578X2311702
Ginkgo biloba extract (GBE) is an essential herbal supplement for diverse health perspectives. The present study aims to improve the oral bioavailability of GBE flavonoids. We formulated the GBE flavonoids-cyclodextrin (GBE-CD) complex by reacting GB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc1b2378e8182ba78cf494ba38bdef40
https://doi.org/10.1177/1934578x231170221
https://doi.org/10.1177/1934578x231170221
Autor:
Hiroshi Yamagata, Tsubasa Saito, Takezo Okamoto, Kensuke Satomoto, Tatsuya Mitsumoto, Atsushi Wakita, Maki Nakamura, Takahiro Hayashi, Yuichi Kuroiwa
Publikováno v:
Journal of toxicologic pathology. 35(4)
The carcinogenicity of 2,2'-[1,2-ethanediylbis(oxymethylene)]bis-oxirane (ethylene glycol diglycidyl ether; EGDE), 3-hydroxy-2-naphthoic acid (HNA), and acetoacetanilide (AAA) was investigated using a medium-term rat liver bioassay for an occupationa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af086c1ef8e844a45f12bf9dac270da3
https://pubmed.ncbi.nlm.nih.gov/36406173
https://pubmed.ncbi.nlm.nih.gov/36406173
Autor:
Yasunori Masubuchi, Kensuke Satomoto, Shuzo Okazaki, Hiroyuki Uemura, Yousuke Oshima, Yuichi Kuroiwa
Publikováno v:
The Journal of Toxicological Sciences. 37:645-647
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60d19dddcfd5bd25010a54a986e262f
https://doi.org/10.2131/jts.37.645
https://doi.org/10.2131/jts.37.645
Autor:
Kensuke Satomoto, Yasufumi Ueda, Shiro Yoshioka, Sayaka Inagaki, Naoki Shibata, Hirofumi Komori, Yoshiki Higuchi, Shigetoshi Aono
Publikováno v:
Acta crystallographica. Section F, Structural biology and crystallization communications. 62(Pt 5)
CooA, a homodimeric haem-containing protein, is responsible for transcriptional regulation in response to carbon monoxide (CO). It has a b-type haem as a CO sensor. Upon binding CO to the haem, CooA binds promoter DNA and activates expression of gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe7ae5af838f5218f62a886b14fee4c
https://pubmed.ncbi.nlm.nih.gov/16682779
https://pubmed.ncbi.nlm.nih.gov/16682779
Autor:
Hiroshi Yamagata1 yamagata-hiroshi@bozo.co.jp, Tsubasa Saito2, Takezo Okamoto1, Kensuke Satomoto1, Tatsuya Mitsumoto1, Atsushi Wakita3, Maki Nakamura4, Takahiro Hayashi4, Yuichi Kuroiwa1
Publikováno v:
Journal of Toxicologic Pathology. 2022, Vol. 35 Issue 4, p313-320. 8p.