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pro vyhledávání: '"Kensuke Sadaoka"'
Autor:
Kohji Noguchi, Yu Kato, Shingo Kondo, Chihiro Takahashi, Yoshikazu Sugimoto, Shuhei Ishizuka, Kensuke Sadaoka
Publikováno v:
Biochemical and Biophysical Research Communications. 530:230-234
JQ1 disrupts the binding of bromodomain and extra-terminal (BET) family of proteins to acetylated histones, modulates the expression of various genes, and inhibits the proliferation of cancer cells. We established two JQ1-resistant sublines from huma