Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Kensuke OKADA"'
Autor:
Daisuke Ito, Kensuke Okada
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 12, Pp 3054-3063 (2024)
Abstract Antisense oligonucleotides, which are used to silence target genes, are gaining attention as a novel drug discovery modality for proteinopathies. However, while clinical trials for neurodegenerative diseases like amyotrophic lateral sclerosi
Externí odkaz:
https://doaj.org/article/fa2677ed35a846d1885a8fe818c71dc7
Autor:
Chris Kato, Koji Ueda, Satoru Morimoto, Shinichi Takahashi, Shiho Nakamura, Fumiko Ozawa, Daisuke Ito, Yugaku Daté, Kensuke Okada, Naoki Kobayashi, Jin Nakahara, Hideyuki Okano
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-18 (2024)
Abstract Background Extracellular vesicles (EVs) hold the potential for elucidating the pathogenesis of amyotrophic lateral sclerosis (ALS) and serve as biomarkers. Notably, the comparative and longitudinal alterations in the protein profiles of EVs
Externí odkaz:
https://doaj.org/article/166542d458c04fcaa788a27b67f26db5
Autor:
Miyu Sugiyama, Takane Ozawa, Kunihiro Ohta, Kensuke Okada, Teruyuki Niimi, Katsushi Yamaguchi, Shuji Shigenobu, Yasukazu Okada
Publikováno v:
PLoS Genetics, Vol 19, Iss 12, p e1011069 (2023)
For understanding the evolutionary mechanism of sexually selected exaggerated traits, it is essential to uncover its molecular basis. By using broad-horned flour beetle that has male-specific exaggerated structures (mandibular horn, head horn and gen
Externí odkaz:
https://doaj.org/article/b584bb25866a43a8963df6c67a716193
Publikováno v:
Plant Production Science, Vol 24, Iss 4, Pp 454-465 (2021)
The self-sufficiency ratio and national average yield of wheat are low in Japan. Reducing the yield gap and receiving the government subsidy for grain quality are vital strategies for profitability. Elucidating optimum nitrogen application scheme is
Externí odkaz:
https://doaj.org/article/4eceac14ffdb44389debedd0594af5be
Autor:
Kensuke Okada, Masako Katsuki, Manmohan D. Sharma, Katsuya Kiyose, Tomokazu Seko, Yasukazu Okada, Alastair J. Wilson, David J. Hosken
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Natural and sexual selection can be in opposition favouring different trait sizes, but disentangling these processes empirically is difficult. Here Okada et al. show that predation on males shifts the balance of selection in experimentally evolving b
Externí odkaz:
https://doaj.org/article/b7542201cb5e48e3993ff06ad44f4f49
Autor:
Munenori Oyama, Kensuke Okada, Masayuki Masuda, Yuko Shimizu, Kazumasa Yokoyama, Akiyuki Uzawa, Naoki Kawaguchi, Ryotaro Ikeguchi, Yasunobu Hoshino, Taku Hatano, Yukiko Ozawa, Jin Nakahara, Hitoshi Aizawa, Kazuo Kitagawa, Nobutaka Hattori, Satoshi Kuwabara, Hiroyuki Murai, Shigeaki Suzuki
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 13 (2020)
Background: Eculizumab is a humanized monoclonal antibody that targets complement protein C5 and inhibits terminal complement-mediated damage at the neuromuscular junction. Recently, the REGAIN study showed that eculizumab was effective and well tole
Externí odkaz:
https://doaj.org/article/81fb81d66156442cb9f4fe3e8f53dd7a
Autor:
Sonali Hasmukh Chauhan, Santosh Yadav, Taro Takahashi, Łukasz Łuczaj, Lancelot D’Cruz, Kensuke Okada
Publikováno v:
Journal of Ethnobiology and Ethnomedicine, Vol 14, Iss 1, Pp 1-20 (2018)
Abstract Background Wild edibles continue to be a significant contributor to the global food basket in much of the developing world. A consensus has now been formed that information on wild edibles is an important part of ethnobotanical knowledge and
Externí odkaz:
https://doaj.org/article/5fb457c82b3947589167879deee51b46
Publikováno v:
PLoS Biology, Vol 17, Iss 11, p e3000541 (2019)
Evolutionarily conserved insulin/insulin-like growth factor (IGF) signaling (IIS) has been identified as a major physiological mechanism underlying the nutrient-dependent regulation of sexually selected weapon growth in animals. However, the molecula
Externí odkaz:
https://doaj.org/article/2b3f389669f74aba8558882f2c2e44c3
Publikováno v:
Journal of Fluid Science and Technology, Vol 14, Iss 2, Pp JFST0008-JFST0008 (2019)
A wind tunnel experiment was performed to investigate the suitable conditions in which a localized turbulent region can easily be generated in a flat-plate boundary layer. An artificial disturbance of zero-mass flux was introduced upstream using a co
Externí odkaz:
https://doaj.org/article/5dcf35852ff149d382a9760d24911ac1
Comparison among cognitive diagnostic models for the TIMSS 2007 fourth grade mathematics assessment.
Autor:
Kazuhiro Yamaguchi, Kensuke Okada
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0188691 (2018)
A variety of cognitive diagnostic models (CDMs) have been developed in recent years to help with the diagnostic assessment and evaluation of students. Each model makes different assumptions about the relationship between students' achievement and ski
Externí odkaz:
https://doaj.org/article/84f0a179142448638a5105cf2fee1f71