Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kensho Suzuki"'
Autor:
Ken Morita, Shintaro Maeda, Kensho Suzuki, Hiroki Kiyose, Junichi Taniguchi, Pu Paul Liu, Hiroshi Sugiyama, Souichi Adachi, Yasuhiko Kamikubo
Publikováno v:
Blood Advances, Vol 1, Iss 18, Pp 1440-1451 (2017)
Abstract: Besides being a classical tumor suppressor, runt-related transcription factor 1 (RUNX1) is now widely recognized for its oncogenic role in the development of acute myeloid leukemia (AML). Here we report that this bidirectional function of R
Externí odkaz:
https://doaj.org/article/5ef046fb3d1c469a978c32af4f0e1100
Autor:
Tatsuya Masuda, Shintaro Maeda, Sae Shimada, Naoya Sakuramoto, Ken Morita, Asami Koyama, Kensho Suzuki, Yoshihide Mitsuda, Hidemasa Matsuo, Hirohito Kubota, Itaru Kato, Kuniaki Tanaka, Junko Takita, Masahiro Hirata, Tatsuki R Kataoka, Tatsutoshi Nakahata, Souichi Adachi, Hideyo Hirai, Shuichi Mizuta, Kazuhito Naka, Yoichi Imai, Shinya Kimura, Hiroshi Sugiyama, Yasuhiko Kamikubo
Publikováno v:
Cancer Science. 113(2):529-539
The emergence of tyrosine kinase inhibitors as part of a front-line treatment has greatly improved the clinical outcome of the patients with Ph⁺ acute lymphoblastic leukemia (ALL). However, a portion of them still become refractory to the therapy m
Autor:
Kensho Suzuki, Kohei Henmi, Shota Nakagawa, Satoshi Teramukai, Tetsuro Takamatsu, Ryo Fujita, Kengo Ueno, Yuichi Inoue, Masatomo Kaneko, Keiichi Masuda, Keisuke Tsuji, Osamu Ukimura, Eiichi Konishi
Publikováno v:
BJU internationalReferences. 130(2)
OBJECTIVES To develop a classification system for urine cytology with artificial intelligence (AI) using a convolutional neural network algorithm that classifies urine cell images as negative (benign) or positive (atypical or malignant). PATIENTS AND
Autor:
Shota Nakagawa, Yuichi Inoue, Ryo Fujita, Keisuke Tsuji, Kohei Henmi, Osamu Ukimura, Masatomo Kaneko, Keiichi Masuda, Hikaru Shindo, Kengo Ueno, Eiichi Konishi, Tetsuro Takamatsu, Kensho Suzuki
Publikováno v:
Journal of Urology. 203
INTRODUCTION AND OBJECTIVE:Urine cytology is a noninvasive and inexpensive screening test, however, the sensitivity is low with respect to low grade urothelial cancer. In addition, urine cytology h...
Autor:
Hiroki Kiyose, Shintaro Maeda, Ken Morita, Pengfei Liu, Yasuhiko Kamikubo, Kensho Suzuki, Souichi Adachi, Hiroshi Sugiyama, Junichi Taniguchi
Publikováno v:
Blood Advances. 1:1440-1451
Besides being a classical tumor suppressor, runt-related transcription factor 1 (RUNX1) is now widely recognized for its oncogenic role in the development of acute myeloid leukemia (AML). Here we report that this bidirectional function of RUNX1 possi
Autor:
Chieko Tokushige, Shintaro Maeda, Masahiro Hirata, Akihiko Matsuo, Ayaka Yano, Toshikazu Bando, Paul P. Liu, Sunao Tanaka, Kosei Ito, Tatsuki R. Kataoka, Hiroki Kiyose, Mayu Tokumasu, Hidemasa Matsuo, Mina Noura, Gengo Kashiwazaki, Yasuhiko Kamikubo, Ken Morita, Manabu Muto, Yasufumi Kaneda, Yasushi Okuno, Kazuhito Naka, Rina Maeda, Yoshimi Yamada, Yoshihide Mitsuda, Kensho Suzuki, Hiroshi Sugiyama, Junichi Taniguchi, Souichi Adachi, Toshio Kitamura
Publikováno v:
Journal of Clinical Investigation. 127:2815-2828
Runt-related transcription factor 1 (RUNX1) is generally considered to function as a tumor suppressor in the development of leukemia, but a growing body of evidence suggests that it has pro-oncogenic properties in acute myeloid leukemia (AML). Here w
Autor:
Gengo Kashiwazaki, Yoshihide Mitsuda, Yasuhiko Kamikubo, Toshikazu Bando, Shintaro Maeda, Hiroshi Sugiyama, Junichi Taniguchi, Ken Morita, Kensho Suzuki, Souichi Adachi
Publikováno v:
Cancer Research. 77:1530-1530
Although runt-related transcription factor 1 (RUNX1) is well known for its context-dependent oncogenic properties in various malignancies, its role in gastric cancers has been poorly defined. Up-regulation of receptor tyrosine kinase (RTK) ErbB2/HER2
Publikováno v:
Blood. 128:2710-2710
Although Runt-related transcription factor 1 (RUNX1), a member of RUNX transcription family, is known for its oncogenic role in the development of acute myeloid leukemia (AML), evidence from other groups support the oncosuppressive property of RUNX1
Autor:
Kensho Suzuki, Souichi Adachi, Shintaro Maeda, Hiroshi Sugiyama, Yasuhiko Kamikubo, Ken Morita
Publikováno v:
Blood. 128:2737-2737
Philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ALL) is caused by reciprocal translocation between chromosome 9 (region q34) and chromosome 22 (region q11). This translocation results in oncogenic BCR-ABL fusion gene that encodes a
Autor:
Ken Morita1,2, Kensho Suzuki1, Shintaro Maeda1, Akihiko Matsuo1, Yoshihide Mitsuda1, Chieko Tokushige1, Gengo Kashiwazaki3, Junichi Taniguchi3, Rina Maeda3, Noura, Mina1, Masahiro Hirata4, Tatsuki Kataoka4, Ayaka Yano1, Yoshimi Yamada1, Hiroki Kiyose1, Mayu Tokumasu1, Hidemasa Matsuo1, Sunao Tanaka1, Yasushi Okuno1, Manabu Muto5
Publikováno v:
Journal of Clinical Investigation. Jul2017, Vol. 127 Issue 7, p2815-2828. 14p. 2 Color Photographs, 7 Graphs.