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pro vyhledávání: '"Kensey Stansberry-Perkins"'
Publikováno v:
Journal of pharmaceutical sciences. 111(11)
Over seventy percent of marketed monoclonal antibody therapeutics contain between 0.001% and 0.1% (w/v) polysorbate, as it has a generally beneficial stabilizing effect that increases drug product shelf life. However, polysorbate has also been shown
Autor:
Kensey Stansberry-Perkins, Alex Buko, Ying Zhang, Mark L. Brader, Vanessa Nguyen, Shujun Bai, Sharon X. Gao
Publikováno v:
Biotechnology and bioengineering. 108(4)
Monoclonal antibody (mAb) fragmentation can be a widespread problem across the biotechnology industry and there is a current need to better understand the underlying principles. Here, we report an example of a high-purity human IgG1 mAb prepared from