Výsledky vyhledávání - "Kenro, Utsunomiya"

Cbl-b is a critical regulator of macrophage activation associated with obesity-induced insulin resistance in mice

Autor: Takeshi Nikawa, Edward M. Mills, Yuushi Okumura, Katsuya Hirasaka, Kenro Utsunomiya, Atsuko Sakai, Arisa Ochi, Motoko Oarada, Tomoki Abe, Shohei Kohno, Sachiko Kagawa, Shigetada Teshima-Kondo, Ayako Ohno, Junji Terao, Yoichi Maekawa

Publikováno v: Diabetes

We previously reported the potential involvement of casitas B-cell lymphoma-b (Cbl-b) in aging-related murine insulin resistance. Because obesity also induces macrophage recruitment into adipose tissue, we elucidated here the role of Cbl-b in obesity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36582b382bc0cbad5db21cf43b5bb35
https://pubmed.ncbi.nlm.nih.gov/23349502

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An intracellular fragment of osteoactivin formed by ectodomain shedding translocated to the nucleoplasm and bound to RNA binding proteins

Autor: Shigetada Teshima-Kondoh, Ayako Ohno, Takahiro Oto, Kanako Owaki, Takeshi Nikawa, Momoko Yano, Shohei Kohno, Seiko Tamura, Eri Suzuki, Yuushi Okumura, Kenro Utsunomiya, Tomoki Abe, Katsuya Hirasaka

Publikováno v: Bioscience, biotechnology, and biochemistry. 76(12)

Osteoactivin is a type I transmembrane protein upregulated by unloading stresses, including denervation, prolonged bed rest, and space flight, but the regulatory mechanisms of its expression and activation under these conditions remain undefined. Her

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81f3f5d4b1d34a471e82c21a1b8ab74
https://pubmed.ncbi.nlm.nih.gov/23221696

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[Space flight/bedrest immobilization and bone. Development of inhibitors for atrophy caused by unloading stress]

Autor: Shigetada, Kondo, Ochi, Arisa, Shohei, Kohno, Tomoki, Abe, Kenro, Utsunomiya, Hikaru, Nagano, Takuro, Suto, Chisato, Tomida, Naoko, Yamagishi, Katsuya, Hirasaka, Ayako, Maita, Yushi, Okumura, Takeshi, Nikawa

Publikováno v: Clinical calcium. 22(12)

Muscle atrophy caused by unloading stress is a serious problem in bed rest patients or astronauts. In our previous studies, we revealed that induction and activation of ubiquitin ligase Cbl-b played an important role in skeletal muscle atrophy caused

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::63a634f28de8d82b95f45c562f9deb9a
https://pubmed.ncbi.nlm.nih.gov/23187081

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