Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kenny X.F. Yang"'
Publikováno v:
Anaesthesia and intensive care. 47(2)
Clonidine has been used successfully to prolong the duration of action of local anaesthetics in peripheral nerve blocks, but its mechanism of action in this setting remains unclear. Some studies suggest that clonidine exerts a vasoconstrictor effect,
Autor:
Kenny X.F. Yang, Judith L. Black
Publikováno v:
European Journal of Pharmacology. 315:65-71
Activation of protein kinase C by phorbol 12,13-dibutyrate (PDB) (1 nM-3 microM) caused a concentration-dependent contractile response in human isolated bronchus. The mean maximal contraction was 26 +/- 4.4% (n = 11) of that induced by acetylcholine
Publikováno v:
The American journal of physiology. 276(3)
Protein kinase C (PKC) is implicated in the regulation of smooth muscle contractility and growth. We have previously described the pattern of isoform expression of PKC in canine airway smooth muscle. This study identified the isoforms present in huma
Autor:
Judith L. Black, Kenny X.F. Yang
Publikováno v:
European journal of pharmacology. 275(3)
The involvement of protein kinase C in the contraction of airway smooth muscle has been investigated in human isolated bronchus. Phorbol 12,13-dibutyrate (PDB) (10 microM) produced aw biphasic response--relaxation followed by contraction. The protein