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pro vyhledávání: '"Kenny K K Chung"'
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232019 (2020)
Parkinson's disease (PD) is a common neurodegenerative disorder which is mostly sporadic but familial-linked PD (FPD) cases have also been found. The first reported gene mutation that linked to PD is α-synuclein (α-syn). Studies have shown that mut
Externí odkaz:
https://doaj.org/article/1a8604ce336d431bacd17b71393c337b
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0235296 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0232019.].
Externí odkaz:
https://doaj.org/article/8e96e04f1d5241318e179d93b6038322
Autor:
Oi Wan Wan, Kenny K K Chung
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38545 (2012)
α-Synuclein (α-syn) is a synaptic protein in which four mutations (A53T, A30P, E46K and gene triplication) have been found to cause an autosomal dominant form of Parkinson's disease (PD). It is also the major component of intraneuronal protein aggr
Externí odkaz:
https://doaj.org/article/73262ef28efa43ddb0afcd1e7f266c4a
Autor:
Kenny K K, Chung
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1292
Parkinson's disease (PD) is marked by a selective degeneration of dopaminergic neurons in the brain stem and it is the second most common neurodegenerative disorder. The pathogenic mechanism of PD is not completely known but it is believed that oxida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c2ef15a6ab461b41872a9956b30cb910
https://pubmed.ncbi.nlm.nih.gov/25804757
https://pubmed.ncbi.nlm.nih.gov/25804757
Autor:
Weilin, Xie, Kenny K K, Chung
Publikováno v:
Journal of neurochemistry. 122(2)
Alpha-synuclein (α-syn) is a synaptic protein that mutations have been linked to Parkinson's disease (PD), a common neurodegenerative disorder that is caused by the degeneration of the dopaminergic neurons in the substantia nigra pars compacta (SNc)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::679b3f32a2c0c447f2704e9e785d7f0d
https://pubmed.ncbi.nlm.nih.gov/22537068
https://pubmed.ncbi.nlm.nih.gov/22537068
Publikováno v:
Methods in enzymology. 396
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by impairment in motor function. PD is mostly sporadic, but rare familial cases are also found. The exact pathogenic mechanism is not fully understood, but both genetic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f4a26214c90b46c1a2450f2b39d8a24
https://pubmed.ncbi.nlm.nih.gov/16291229
https://pubmed.ncbi.nlm.nih.gov/16291229