Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Kenny Helsens"'
Autor:
Petra Van Damme, Kristine Hole, Ana Pimenta-Marques, Kenny Helsens, Joël Vandekerckhove, Rui G Martinho, Kris Gevaert, Thomas Arnesen
Publikováno v:
PLoS Genetics, Vol 7, Iss 7, p e1002169 (2011)
N-terminal acetylation (N-Ac) is a highly abundant eukaryotic protein modification. Proteomics revealed a significant increase in the occurrence of N-Ac from lower to higher eukaryotes, but evidence explaining the underlying molecular mechanism(s) is
Externí odkaz:
https://doaj.org/article/fd60a41182c447e8a7aa78b656a5c122
Autor:
Jo Vandesompele, Björn Menten, Lennart Martens, Kenny Helsens, Xiaowei Wang, Pieter-Jan Volders, Kris Gevaert, Pieter Mestdagh
Publikováno v:
NUCLEIC ACIDS RESEARCH
Nucleic Acids Research
Nucleic Acids Research
Here, we present LNCipedia (http://www.lncipedia.org), a novel database for human long non-coding RNA (lncRNA) transcripts and genes. LncRNAs constitute a large and diverse class of non-coding RNA genes. Although several lncRNAs have been functionall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471f03924d68616249848c45e817fb78
https://doi.org/10.1093/nar/gks915
https://doi.org/10.1093/nar/gks915
Autor:
Kim Plasman, Davy Maddelein, Kris Gevaert, Lennart Martens, Petra Van Damme, Kenny Helsens, Niels Hulstaert, Niklaas Colaert, Joël Vandekerckhove, Francis Impens
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research; Vol 41
NUCLEIC ACIDS RESEARCH
Nucleic Acids Research; Vol 41
NUCLEIC ACIDS RESEARCH
We here present The Online Protein Processing Resource (TOPPR; http://iomics.ugent.be/toppr/), an online database that contains thousands of published proteolytically processed sites in human and mouse proteins. These cleavage events were identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c04455967837e7675c39a6ed47653aa
http://europepmc.org/articles/PMC3531153
http://europepmc.org/articles/PMC3531153
Publikováno v:
PROTEOMICS
PROTEOMICS; Vol 12
PROTEOMICS; Vol 12
We have created a new software platform called sigpep that analyzes transition redundancy in selected reaction monitoring assays. Building on this platform, we also created a web application to generate transition sets with unique signatures for targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d53c60b8b4f10491942a9684b3ea90c
Publikováno v:
Journal of Proteome Research
Proteome identification using peptide-centric proteomics techniques is a routinely used analysis technique. One of the most powerful and popular methods for the identification of peptides from MS/MS spectra is protein database matching using search e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bfed307d1d1d6ba86b1e4d441f92e8
https://doi.org/10.1021/pr200913a
https://doi.org/10.1021/pr200913a
Autor:
Kenny Helsens, Petra Van Damme, Kris Gevaert, Sven Degroeve, Joël Vandekerckhove, Thomas Arnesen, Lennart Martens
Publikováno v:
Journal of Proteome Research. 10:3578-3589
Initiation of protein translation is a well-studied fundamental process, albeit high-throughput and more comprehensive determination of the exact translation initiation sites (TIS) was only recently made possible following the introduction of positio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237e54bf39f528ad2577868b26ee7d28
https://doi.org/10.1021/pr2002325
https://doi.org/10.1021/pr2002325
Publikováno v:
PROTEOMICS. 11:1094-1098
Tyrosine nitration is the consequence of a complex machinery of formation and merging of oxygen and nitrogen radicals, and has been associated with both physiological pathways as well as with several human diseases. The latter turned this posttransla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98e6e23ec7c9080c21e555725c4a05e
https://doi.org/10.1002/pmic.201000526
https://doi.org/10.1002/pmic.201000526
Autor:
Lennart Martens, Kenny Helsens, Harald Barsnes, Marc Vaudel, Niklaas Colaert, Kris Gevaert, Evy Timmerman, Albert Sickmann
Publikováno v:
Journal of Proteome Research
Journal of Proteome Research; Vol 10
Journal of Proteome Research; Vol 10
The Thermo Proteome Discoverer program integrates both peptide identification and quantification into a single workflow for peptide-centric proteomics. Furthermore, its close integration with Thermo mass spectrometers has made it increasingly popular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34fd6cec936f559718dbcc2b90696f37
Autor:
Niklaas Colaert, Evy Timmerman, An Staes, Joël Vandekerckhove, Francesc X. Avilés, Kenny Helsens, Petra Van Damme, Sílvia Bronsoms, Kris Gevaert
Publikováno v:
Nature Methods. 7:512-515
We describe a positional proteomics approach to simultaneously analyze N- and C-terminal peptides and used it to screen for human protein substrates of granzyme B and carboxypeptidase A4 in human cell lysates. This approach allowed comprehensive prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810b6c6ececac7c92e15e6339b30f3ed
https://doi.org/10.1038/nmeth.1469
https://doi.org/10.1038/nmeth.1469
Autor:
Kim Plasman, Joël Vandekerckhove, Kris Gevaert, Petra Van Damme, Kenny Helsens, Francis Impens, Niklaas Colaert
Publikováno v:
PROTEOMICS. 10:1284-1296
Proteolytic processing has recently received increased attention in the field of signal propagation and cellular differentiation. Because of its irreversible nature, protein cleavage has been associated with committed steps in cell function. One aspe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::431dbfa79654a1c84eee068e30e5d6f2
https://doi.org/10.1002/pmic.200900418
https://doi.org/10.1002/pmic.200900418