Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kennon Smith"'
Autor:
Mario Mietzsch, J. Kennon Smith, Jennifer C. Yu, Vibhu Banala, Shanan N. Emmanuel, Ariana Jose, Paul Chipman, Nilakshee Bhattacharya, Robert McKenna, Mavis Agbandje-McKenna
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 362-373 (2020)
Affinity-based purification of adeno-associated virus (AAV) vectors has replaced density-based methods for vectors used in clinical settings. This method utilizes camelid single-domain antibodies recognizing AAV capsids. These include AVB Sepharose (
Externí odkaz:
https://doaj.org/article/28d7c2f26301459a88a2ed347f353059
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 1-7 (2018)
Adeno-associated virus (AAV) is one of the most promising gene therapy vectors and is widely used as a gene delivery vehicle for basic research. As AAV continues to become the vector of choice, it is increasingly important for new researchers to have
Externí odkaz:
https://doaj.org/article/5972475078d046ec94ec1dbed7084cf3
Structural Characterization of Cuta- and Tusavirus: Insight into Protoparvoviruses Capsid Morphology
Autor:
Mario Mietzsch, Robert McKenna, Elina Väisänen, Jennifer C. Yu, Maria Ilyas, Joshua A. Hull, Justin Kurian, J. Kennon Smith, Paul Chipman, Yi Lasanajak, David Smith, Maria Söderlund-Venermo, Mavis Agbandje-McKenna
Publikováno v:
Viruses, Vol 12, Iss 6, p 653 (2020)
Several members of the Protoparvovirus genus, capable of infecting humans, have been recently discovered, including cutavirus (CuV) and tusavirus (TuV). To begin the characterization of these viruses, we have used cryo-electron microscopy and image r
Externí odkaz:
https://doaj.org/article/e99c377f263140b48244571e8bed3873
Autor:
J Kennon Smith, Mavis Agbandje-McKenna
Publikováno v:
PLoS Pathogens, Vol 14, Iss 5, p e1006929 (2018)
The Adeno-associated virus (AAV) gene delivery system is ushering in a new and exciting era in the United States; following the first approved gene therapy (Glybera) in Europe, the FDA has approved a second therapy, Luxturna [1]. However, challenges
Externí odkaz:
https://doaj.org/article/24fa8eeee3bf43a5988d78fdf7d689a8
Autor:
Nilakshee Bhattacharya, Ariana Jose, Jennifer C. Yu, J. Kennon Smith, Shanan N Emmanuel, Mario Mietzsch, Vibhu Banala, Mavis Agbandje-McKenna, Paul R. Chipman, Robert McKenna
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 362-373 (2020)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Affinity-based purification of adeno-associated virus (AAV) vectors has replaced density-based methods for vectors used in clinical settings. This method utilizes camelid single-domain antibodies recognizing AAV capsids. These include AVB Sepharose (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1e9858e7671d3535f990872bfb70c3
http://www.sciencedirect.com/science/article/pii/S2329050120302059
http://www.sciencedirect.com/science/article/pii/S2329050120302059
Autor:
Yu-Shan Tseng, J. Kennon Smith, Mario Mietzsch, Aravind Asokan, Robert McKenna, Shanan N Emmanuel, Mavis Agbandje-McKenna, Jane Hsi, Matias Kaplan, Paul R. Chipman
Publikováno v:
J Virol
Adeno-associated viruses (AAV) serve as vectors for therapeutic gene delivery. AAV9 vectors have been FDA approved, as Zolgensma, for the treatment of spinal muscular atrophy and are being evaluated in clinical trials for the treatment of neurotropic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1481ded89cf7a846c284dde2447310
https://europepmc.org/articles/PMC8827038/
https://europepmc.org/articles/PMC8827038/
Autor:
Neha Potnis, Gerald Minsavage, J. Kennon Smith, Jason C. Hurlbert, David Norman, Rosana Rodrigues, Robert E. Stall, Jeffrey B. Jones
Publikováno v:
Molecular Plant-Microbe Interactions, Vol 25, Iss 3, Pp 307-320 (2012)
A novel hypersensitive resistance (HR) in Capsicum baccatum var. pendulum against the bacterial spot of pepper pathogen, Xanthomonas gardneri, was introgressed into C. annuum cv. Early Calwonder (ECW) to create the near-isogenic line designated as EC
Externí odkaz:
https://doaj.org/article/e43b6192054a45e8b05a8f396dd62227
Autor:
Maria Ilyas, Mario Mietzsch, Shweta Kailasan, Elina Väisänen, Mengxiao Luo, Paul Chipman, J. Kennon Smith, Justin Kurian, Duncan Sousa, Robert McKenna, Maria Söderlund-Venermo, Mavis Agbandje-McKenna
Publikováno v:
Viruses, Vol 10, Iss 1, p 22 (2018)
Bufavirus strain 1 (BuV1), a member of the Protoparvovirus genus of the Parvoviridae, was first isolated from fecal samples of children with acute diarrhea in Burkina Faso. Since this initial discovery, BuVs have been isolated in several countries, i
Externí odkaz:
https://doaj.org/article/27c333f1ff9c4748bb9a1fd6917baaa1
Autor:
Nikéa Pittman, Adam Misseldine, Lorena Geilen, Sujata Halder, J. Kennon Smith, Justin Kurian, Paul Chipman, Mandy Janssen, Robert Mckenna, Timothy S. Baker, Anthony D’Abramo Jr., Susan Cotmore, Peter Tattersall, Mavis Agbandje-McKenna
Publikováno v:
Viruses, Vol 9, Iss 11, p 321 (2017)
LuIII, a protoparvovirus pathogenic to rodents, replicates in human mitotic cells, making it applicable for use to kill cancer cells. This virus group includes H-1 parvovirus (H-1PV) and minute virus of mice (MVM). However, LuIII displays enhanced on
Externí odkaz:
https://doaj.org/article/b036ccfcc40b4c499f9922879e35ccf3
Autor:
Maria Ilyas, Jennifer C. Yu, Robert McKenna, David L. Smith, Paul R. Chipman, Joshua A. Hull, Yi Lasanajak, J. Kennon Smith, Elina Väisänen, Mario Mietzsch, Maria Söderlund-Venermo, Mavis Agbandje-McKenna, Justin J. Kurian
Publikováno v:
Viruses
Viruses, Vol 12, Iss 653, p 653 (2020)
Volume 12
Issue 6
Viruses, Vol 12, Iss 653, p 653 (2020)
Volume 12
Issue 6
Several members of the Protoparvovirus genus, capable of infecting humans, have been recently discovered, including cutavirus (CuV) and tusavirus (TuV). To begin the characterization of these viruses, we have used cryo-electron microscopy and image r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a42c24d15a77121745815298672b848
http://hdl.handle.net/10138/319108
http://hdl.handle.net/10138/319108