Výsledky vyhledávání - "Kennita Johnson"

Autor: Kennita Johnson

Publikováno v: Scopus-Elsevier

Imaging is a noninvasive complement to traditional methods (such as histology) in rodent cardiac studies. Assessments of structure and function are possible with ultrasound, microcomputed tomography (microCT), and magnetic resonance (MR) imaging. Car

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717e0940eb949d4c00f84e675b7cf408
https://doi.org/10.1093/ilar.49.1.27

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Hepatic Transcript Levels for Genes Coding for Enzymes Associated with Xenobiotic Metabolism are Altered with Age

Autor: Edward K. Lobenhofer, Joseph H. Roycroft, Joel S. Parker, Gary A. Boorman, Kimwa L. Walker, Kazuhiko Mori, Tiwanda Marsh, Pamela E. Blackshear, Denise Orzech, Kennita Johnson, Richard D. Irwin

Publikováno v: Toxicologic Pathology. 35:242-251

Metabolism studies are crucial for data interpretation from rodent toxicity and carcinogenicity studies. Metabolism studies are usually conducted in 6 to 8 week old rodents. Long-term studies often continue beyond 100 weeks of age. The potential for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99d7df94fd34e8744a3111d4d6af0fd
https://doi.org/10.1080/01926230601156286

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Application of magnetic resonance imaging in developmental neurotoxicity testing: A pilot study

Autor: Linda Ryan, Amy Elmore, Brett Guenther, Robert R. Maronpot, Jeffrey Davis, Jill Marcus, Kennita Johnson

Publikováno v: NeuroToxicology. 27:846-851

In a pilot developmental neurotoxicity study, a protocol was designed to utilize three-dimensional magnetic resonance (MR) images for linear and volumetric measurements of the developing rat brain. MR imaging, because of its non-destructive nature, p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a21d7bd358deb8eaea18f9e239d648
https://doi.org/10.1016/j.neuro.2006.06.005

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Improving the quantitative ability of contrast enhanced ultrasound perfusion imaging: effect of contrast administration rate and imaging plane orientation

Autor: Kennita Johnson, Nicholas Garrett, William J. Arendshorst, Steven Feingold, Ismayil M. Guracar, Paul Kogan, Paul A. Dayton

Publikováno v: 2011 IEEE International Ultrasonics Symposium.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a74d0da0816f9db41c57feabf3e2eb71
https://doi.org/10.1109/ultsym.2011.0605

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A pilot study to assess markers of renal damage in the rodent kidney after exposure to 7 MHz ultrasound pulse sequences designed to cause microbubble translation and disruption

Autor: Kennita Johnson, Rachel E. Cianciolo, Ryan C. Gessner, Paul A. Dayton

Publikováno v: Ultrasound in medicinebiology. 38(1)

Acoustic radiation force has been proposed as a mechanism to enhance microbubble concentration for therapeutic and molecular imaging applications. It is hypothesized that once microbubbles are localized, bursting them with acoustic pressure could res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e228aceeac7cf0f8d3b2bdf825278e
https://pubmed.ncbi.nlm.nih.gov/22104535

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Validation of Dynamic Contrast-Enhanced Ultrasound in Rodent Kidneys as an Absolute Quantitative Method for Measuring Blood Perfusion

Autor: Steven Feingold, Kennita Johnson, Paul A. Dayton, Nicholas Garrett, Ismayil M. Guracar, Paul Kogan, William J. Arendshorst

Contrast-enhanced ultrasound (CEUS) has demonstrated utility in the monitoring of blood flow in tissues, organs and tumors. However, current CEUS methods typically provide only relative image-derived measurements, rather than quantitative values of b

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Imaging techniques for small animal imaging models of pulmonary disease: micro-CT

Autor: Kennita Johnson

Publikováno v: Toxicologic pathology. 35(1)

Microcomputed tomography (micro-CT) is ideal for quantifying pulmonary disease because of the inherent contrast between tissue and air that exists in the lungs. Both in vivo and in vitro studies can be performed using micro-CT. Live animal studies sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145b34037f70e6b9096d4bd8bca28577
https://pubmed.ncbi.nlm.nih.gov/17325973

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2-Butoxyethanol female-rat model of hemolysis and disseminated thrombosis: X-ray characterization of osteonecrosis and growth-plate suppression

Autor: Abraham Nyska, Shay Shabat, Danielle N. Lewis, Michael A. Streicker, Sandy M. Ward, Meir Nyska, Shyamal D. Peddada, David E. Malarkey, Kennita Johnson

Publikováno v: Toxicologic pathology. 33(2)

We recently proposed a chemically induced rat model for human hemolytic disorders associated with thrombosis. The objective of the present investigation was to apply a noninvasive, high-magnification X-ray analysis, the Faxitron radiography system, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ed5b41edc0b74bf94c40226a02fcc7
https://pubmed.ncbi.nlm.nih.gov/15902971

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New insights into functional aspects of liver morphology

Autor: Robert R. Maronpot, Kennita Johnson, Linda Ryan, David E. Malarkey, Gary A. Boorman

Publikováno v: Toxicologic pathology. 33(1)

The liver is structurally and functionally complex and has been considered second only to brain in its complexity. Many mysteries still exist in this heterogeneous tissue whose functional unit of the lobule has continued to stump morphologists for ov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7745459d4e8c31d7c0bab618053236
https://pubmed.ncbi.nlm.nih.gov/15805053

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