Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kennichi C. Dowdell"'
Autor:
Linhong Li, Harry L. Malech, Kennichi C. Dowdell, Julie Brault, Ezekiel Bello, Sherry Koontz, Aaron B. Clark, Ronald J. Meis, Michael J. Lenardo, Colin L. Sweeney, Narda Theobald, Juan C. Ravell, Janet Lee, Gary A. Dahl, Taylor Liu, Suk See De Ravin, Cornell Allen
Publikováno v:
Cytotherapy. 23:203-210
Background aim X-linked MAGT1 deficiency with increased susceptibility to EBV-infection and N-linked glycosylation defect' (XMEN) disease is caused by mutations in the magnesium transporter 1 (MAGT1) gene. Loss of MAGT1 function results in a glycosyl
Autor:
Ezekiel Bello, Marita Bosticardo, Ronald J. Meis, Sherry Koontz, Shengdar Q. Tsai, Juan C Ravell, Michael J. Lenardo, Luigi D. Notarangelo, Benjamin P. Kleinstiver, Xiaolin Wu, Cicera R. Lazzarotto, Harry L. Malech, Guillaume Vayssière, Kennichi C. Dowdell, Colin L. Sweeney, Gary A. Dahl, Taylor Q. Liu, Aaron B. Clark, Uimook Choi, Cristina Corsino, Suk See De Ravin, Siyuan Liu, Julie Brault
Publikováno v:
Blood
XMEN disease, defined as “X-linked MAGT1 deficiency with increased susceptibility to Epstein-Barr virus infection and N-linked glycosylation defect,” is a recently described primary immunodeficiency marked by defective T cells and natural killer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4b75a7fdafd4fa4d8bff8e2be88729
https://europepmc.org/articles/PMC8718624/
https://europepmc.org/articles/PMC8718624/
Autor:
Francis S. Collins, Jeffrey I. Cohen, Pierce Radecki, Amy J. Swift, Tammy Krogmann, Deborah Tamura, Timothy G. Myers, Lori L. Bonnycastle, Robert Sarkany, Stefania Pittaluga, Hiva Fassihi, Kennichi C. Dowdell, Peter S. Chines, Kelly Liepshutz, Kenneth H. Kraemer, Siu-Ping Turk, Elaine S. Jaffe, Ronald L. Hornung, John J. DiGiovanna, Melissa A. Levoska, Wei Bu, Irini Manoli
Publikováno v:
Blood
Patients with classic hydroa vacciniforme–like lymphoproliferative disorder (HVLPD) typically have high levels of Epstein-Barr virus (EBV) DNA in T cells and/or natural killer (NK) cells in blood and skin lesions induced by sun exposure that are in
Autor:
Sally Hunsberger, Mir A. Ali, John Shon, Hanh Nguyen, Keith Lumbard, Jaymie R Sawyer, Joel Bozekowski, Kening Wang, Jack Reifert, Harlan L Pietz, Doreen Garabedian, Winston A. Haynes, Lesia K. Dropulic, Joshua S Vogel, Kennichi C. Dowdell, Patrick S. Daugherty, Sinthujan Jegaskanda, Makinna C Oestreich, Jeffrey I. Cohen
Publikováno v:
J Infect Dis
Previous herpes simplex virus type 2 (HSV-2) vaccines have not prevented genital herpes. Concerns have been raised about the choice of antigen, the type of antibody induced by the vaccine, and whether antibody is present in the genital tract where in
Autor:
Doreen Garabedian, Kennichi C. Dowdell, Evan Shereck, Geoffrey T. Hart, Julie E. Niemela, Hye Sun Kuehn, Qingxue Li, Lesia K. Dropulic, Laura Schulz, Matthew K. Howe, Tatyana Feldman, Eric O. Long, Jennifer Stoddard, Gulbu Uzel, Jeffrey I. Cohen, Hua Su, Sergio D. Rosenzweig, Kelly Liepshutz, Amy P. Hsu
Publikováno v:
J Infect Dis
Background Chronic active Epstein-Barr virus (CAEBV) presents with high levels of viral genomes in blood and tissue infiltration with Epstein-Barr virus (EBV)–positive lymphocytes. The pathogenesis of CAEBV is poorly understood. Methods We evaluate
Autor:
A. Roy, Kennichi C. Dowdell, Matthew K. Howe, Jeffrey I. Cohen, Joshua McElwee, Julie E. Niemela, Wyndham H. Wilson, Jason D. Hughes
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology
Frontiers in Immunology
Interleukin-2-inducible T cell kinase (ITK) is critical for T cell signaling and cytotoxicity, and control of Epstein-Barr virus (EBV). We identified a patient with a novel homozygous missense mutation (D540N) in a highly conserved residue in the kin
Autor:
Lesia K. Dropulic, Kennichi C. Dowdell, Dennis D. Hickstein, Jana P. Lovell, Nancy M. Hardy, Steven M. Holland, Jeffrey I. Cohen, Amy P. Hsu, Edward W. Cowen, Katherine R. Calvo, Ronald L. Hornung, Stefania Pittaluga, Christa S. Zerbe, Tammy Krogmann
Publikováno v:
Clinical Infectious Diseases. 63:41-47
Background Most patients infected with Epstein-Barr virus (EBV) are asymptomatic, have nonspecific symptoms, or have self-limiting infectious mononucleosis. EBV, however, may result in severe primary disease or cancer. Methods We report EBV diseases
Autor:
Yanmei Wang, Juan C. Lacayo, Rachel B. Gill, Kennichi C. Dowdell, Ron Hornung, Sarah Valencia, Jeffrey I. Cohen, J. Jason Bowman
Publikováno v:
Vaccine. 37(2)
A human cytomegalovirus (HCMV) vaccine to prevent infection and/or reduce disease associated with congenital infection or visceral disease in transplant recipients is a high priority, but has remained elusive. We created a disabled infectious single
Autor:
Kennichi C. Dowdell, Helen E. Heslop, Jennifer Stoddard, Julie E. Niemela, Stefania Pittaluga, Elaine S. Jaffe, Jeffrey I. Cohen
Publikováno v:
Journal of Clinical Immunology. 35:445-448
Severe chronic active Epstein-Barr virus (CAEBV) disease is defined as a severe progressive illness lasting 6 months or longer with infiltration of tissues with EBV-positive lymphocytes, markedly elevated levels of EBV DNA in the blood, and no known
Autor:
Taylor Liu, Ronald J. Meis, Linhong Li, Suk See De Ravin, Juan C. Ravell, Narda Theobald, Michael J. Lenardo, Janet Lee, Ezekiel Bello, Sherry Koontz, Cornell Allen, Harry L. Malech, Kennichi C. Dowdell, Julie Brault, Gary A. Dahl, Aaron B. Clark
Publikováno v:
Blood. 134:4637-4637
Introduction 'X-linked immunodeficiency with magnesium defect, Epstein-Barr virus (EBV) infection, and neoplasia' (XMEN) disease is a primary immunodeficiency disease caused by loss-of-function mutations in the MAGT1 gene encoding for the magnesium t