Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kenneth W. Otis"'
Autor:
Herbert W. Behlow, Michael L. Avery, Kenneth W. Otis, Dennis O. Scott, Suzanne M. Broward-Partin, Thomas N. Thompson, Dannette K. Hansen
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 45:71-77
Combinatorial synthesis and high-throughput pharmacology screening have greatly increased compound throughput in modern drug-discovery programs. For CNS drugs, it is also important to determine permeability to the blood--brain barrier. Yet, given the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09da317121e62a7a1793ad5ce0969c14
https://doi.org/10.1016/s1056-8719(01)00120-4
https://doi.org/10.1016/s1056-8719(01)00120-4
Publikováno v:
Biopharmaceutics & Drug Disposition. 18:743-751
The mass balance of 14C bismuth sucrose octasulfate (BISOS) was investigated in eight male Sprague-Dawley rats after single oral doses of 1.0 g kg-1. Bismuth and radioactivity were monitored in blood, urine, and feces for up to 144 h post-dose, while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b627058ef841c96e4b08dce8bd5d09c9
https://doi.org/10.1002/(sici)1099-081x(199712)18:9<743::aid-bdd62>3.0.co
https://doi.org/10.1002/(sici)1099-081x(199712)18:9<743::aid-bdd62>3.0.co
Publikováno v:
Biopharmaceuticsdrug disposition. 13(9)
The disposition of 4-amino-5-chloro-2-[2-(methylsulfinyl)ethoxy]-N- [2-(diethylamino)ethyl] benzamide hydrochloride (ML-1035) following intravenous (10 mg kg-1) and oral (200 mg kg-1) dosing was investigated in male and female New Zealand white rabbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3310f1d88cc4636dbf0334304b81ff1
https://pubmed.ncbi.nlm.nih.gov/1467455
https://pubmed.ncbi.nlm.nih.gov/1467455