Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Kenneth W Fishbein"'
Autor:
Michael A Petr, Irene Alfaras, Melissa Krawcyzk, Woei-Nan Bair, Sarah J Mitchell, Christopher H Morrell, Stephanie A Studenski, Nathan L Price, Kenneth W Fishbein, Richard G Spencer, Morten Scheibye-Knudsen, Edward G Lakatta, Luigi Ferrucci, Miguel A Aon, Michel Bernier, Rafael de Cabo
Publikováno v:
eLife, Vol 10 (2021)
Aging is associated with distinct phenotypical, physiological, and functional changes, leading to disease and death. The progression of aging-related traits varies widely among individuals, influenced by their environment, lifestyle, and genetics. In
Externí odkaz:
https://doaj.org/article/835e6a3f5fb640ebb35d98290ea431ee
Autor:
Beth G Ashinsky, Kenneth W Fishbein, Erin M Carter, Ping-Chang Lin, Nancy Pleshko, Cathleen L Raggio, Richard G Spencer
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0157891 (2016)
The purpose of this study is to evaluate the ability of quantitative magnetic resonance imaging (MRI) to discriminate between skin biopsies from individuals with osteogenesis imperfecta (OI) and skin biopsies from individuals without OI. Skin biopsie
Externí odkaz:
https://doaj.org/article/d12e28910f144e33ac47adc787e169ad
Autor:
Stephen G. Gonsalves, Leorey N. Saligan, Christopher M. Bergeron, Philip R. Lee, Kenneth W. Fishbein, Richard G. Spencer, Marta Zampino, Xinyi Sun, Jennifer Yeong-Shin Sheng, Vered Stearns, Michael Carducci, Luigi Ferrucci, Nada Lukkahatai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Physical impairments following cancer treatment have been linked with the toxic effects of these treatments on muscle mass and strength, through their deleterious effects on skeletal muscle mitochondrial oxidative capacity. Accordingly, we d
Externí odkaz:
https://doaj.org/article/9a93988e21354dae911d216638a56ee3
Autor:
Yael Yaniv, Magdalena Juhaszova, Su Wang, Kenneth W Fishbein, Dmitry B Zorov, Steven J Sollott
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21985 (2011)
The cardiomyocyte cytoskeleton, composed of rigid and elastic elements, maintains the isolated cell in an elongated cylindrical shape with an elliptical cross-section, even during contraction-relaxation cycles. Cardiomyocyte mitochondria are micron-s
Externí odkaz:
https://doaj.org/article/0b61310b7f60433fa94254227e0a3e28
Autor:
Nicholas A. Brennan, Kenneth W. Fishbein, David A. Reiter, Luigi Ferrucci, Richard G. Spencer
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Skeletal muscle density, as determined by computed tomography (CT), has been shown to decline with age, resulting in increased frailty and morbidity. However, the mechanism underlying this decrease in muscle density remains elusive. We sought to inve
Externí odkaz:
https://doaj.org/article/a50a23e3472f4c129fd24d35b070cf76
Autor:
Donnie Cameron, David A. Reiter, Fatemeh Adelnia, Ceereena Ubaida‐Mohien, Christopher M. Bergeron, Seongjin Choi, Kenneth W. Fishbein, Richard G. Spencer, Luigi Ferrucci
Publikováno v:
Aging Cell.
Autor:
Carla Rocha Dos Santos, Yulia N Grigorova, Ross A McDevitt, Jeffrey M Long, Defne Cezayirli, Valentina Zernetkina, Wen Wei, Mahdi Haghkar, Christopher H Morrell, Ondrej Juhasz, Edward G Lakatta, Richard G Spencer, Peter R. Rapp, Kenneth W Fishbein, Olga V Fedorova
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Christopher H. Morrell, Olga V. Fedorova, Rachel Fenner, Edward G. Lakatta, Defne Cezayirli, Kenneth W. Fishbein, Richard G. Spencer, Samuel Ajamu, Mustapha Bouhrara, Yulia Grigorova
Publikováno v:
Journal of Hypertension
Background Central arterial stiffness (CAS) is associated with elevated arterial blood pressure (BP) and is likely associated with stiffening of cerebral artery walls, with attendant cerebral hypoperfusion, neuronal density loss and cognitive decline
Autor:
Eleanor M. Simonsick, Kenneth W. Fishbein, Nicholas A. Brennan, Pei-Lun Kuo, Luigi Ferrucci, Richard G. Spencer, Marta Zampino
Publikováno v:
GeroScience
Although a persistent inflammatory state has long been associated with aging and negative health outcomes, the underlying mechanisms remain unclear. Mitochondrial dysfunction has been proposed as a cause of inflammaging, but evidence of an associatio
Autor:
Wei Peng, Kenneth W. Fishbein, Mark P. Mattson, Yuyoung Joo, Alexei A. Sharov, Soumita Ghosh, Yongqing Zhang, Simone Bossi, Yi Ding, Henriette van Praag, Keji Zhao, Shuaikun Su, Kevin G. Becker, Weidong Wang, Yutong Xue, Seung Kyu Lee, Weiping Shen, Yue Wang, Aoji Xie, Ross A. McDevitt, Wai Lim Ku, Richard G. Spencer, Nirnath Sah
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications
Topoisomerase 3β (Top3β) is the only dual-activity topoisomerase in animals that can change topology for both DNA and RNA, and facilitate transcription on DNA and translation on mRNAs. Top3β mutations have been linked to schizophrenia, autism, epi