Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kenneth T. Stout"'
Autor:
Breland G. Oscar, Liangdong Zhu, Hayati Wolfendeen, Nikita D. Rozanov, Alvin Chang, Kenneth T. Stout, Jason W. Sandwisch, Joseph J. Porter, Ryan A. Mehl, Chong Fang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Tracking the structural dynamics of fluorescent protein chromophores holds the key to unlocking the fluorescence mechanisms in real time and enabling rational design principles of these powerful and versatile bioimaging probes. By combining recent ch
Externí odkaz:
https://doaj.org/article/d82acd3fb69644c785160f4d74131a09
Publikováno v:
Physical Chemistry Chemical Physics. 21:9728-9739
Green fluorescent protein (GFP) has revolutionized bioimaging and life sciences. Its successes have inspired modification of the chromophore structure and environment to tune emission properties, but outside the protein cage, the chromophore is essen
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 26(70)
A Diels-Alder reaction-based strategy for the synthesis of indoles and related heterocycles is reported. An intramolecular cycloaddition of alkyne-tethered 3-aminopyrones gives 4-substituted indolines in good yield and with complete regioselectivity.
Autor:
Patricia Zhang Musacchio, Ian W. Davies, Robert W Pipal, Stefan Verhoog, Talakad G. Lohith, David Hesk, Alexander Schmitz, Thomas J. A. Graham, Sumei Ren, Hsiaoju S Lee, Eric D. Hostetler, David W. C. MacMillan, Kenneth T Stout, Liza Gantert
Publikováno v:
Nature
Positron emission tomography (PET) radioligands (radioactively labelled tracer compounds) are extremely useful for in vivo characterization of central nervous system drug candidates, neurodegenerative diseases and numerous oncology targets1. Both tri