Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kenneth T. Nakamura"'
Autor:
Jerold M. Stirling, Julie S. Byerley, Lisa E. Leggio, Julia Belkowitz, Chris Peltier, Kenneth T. Nakamura, Michael S. Ryan, Gerard P. Rabalais, Michael A. Barone, Archana Chatterjee
Publikováno v:
The Journal of pediatrics. 191
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 287:L510-L514
The widespread presence of the Na-K-2Cl (NKCC) cotransporter protein suggests that chronic administration of inhibitors may result in adverse effects. Inhibition of the NKCC cotransporter by loop diuretics is felt to underlie the diuretic and the pul
Autor:
Rebecca P. Gelber, Naomi Fujiwara, Kenneth T. Nakamura, G. Andre Marinkovich, Michael J. Christ, Lynn M. Iwamoto
Publikováno v:
Neonatology. 76:98-105
Airway hyperresponsiveness in neonatal chronic lung disease is treated with both furosemide, a diurectic that inhibits the Na-K-2Cl cotrasporter, and salbutamol, a β2-adrenoceptor agonist. Tachyphylaxis to both drugs in vitro has been described. Thi
Autor:
Lynn M. Iwamoto, Kenneth T Nakamura, Vicki L. Wilson, Naomi Fujiwara, Sarah L. Lavallee, Elyse L. Ayau
Publikováno v:
Life Sciences. 59:1015-1024
This in vitro study was conducted to determine whether tachyphylaxis of guinea pig airway to furosemide occurs under conditions that produce tachyphylaxis to the β 2 -adrenoceptor agonist, salbutamol. Isometric tension was measured in tracheal rings
Publikováno v:
Pediatric Research. 38:280-285
We have previously found an age-dependent relaxing effect of furosemide in normal fetal, newborn, and adult guinea pig airways with fetal trachea exhibiting the greatest relaxation and adult tissue the least. This study was designed to expand upon th
Autor:
Venkataraman Balaraman, Kenneth T. Nakamura, Catherine F. T. Uyehara, W. Michael Southgate, Edward L. Stevens, Bruce E. Pichoff
Publikováno v:
Pediatric Pulmonology. 15:105-110
The purpose of this study was to investigate the ontogeny of guinea pig airway smooth muscle (ASM) responses and the epithelial modulation of these responses. Paired tracheal rings from fetal, newborn, and adult guinea pigs were studied. One of each
Autor:
Christian C. Felder, Pedro A. Jose, Anthony M. McKelvey, Jean E. Robillard, Marlene M. Piccio, Kenneth T. Nakamura
Publikováno v:
Pediatric Nephrology. 4:635-639
The renal vasodilatory response to beta-2 adrenoceptor stimulation is greater in fetal than adult sheep. Since this phenomenon could not be explained by differences in cAMP-mediated events, we examined the ontogeny of renal beta adrenoceptor subtypes
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 94(4)
Inhibition of the Na-K-2Cl (NKCC) cotransporter by loop diuretics is associated with airway relaxation, but there has been no direct evidence for the expression of this protein in airway smooth muscle. Thus we hypothesized that a NKCC cotransporter i
Publikováno v:
Pediatric research. 50(2)
This study was designed to test the hypotheses that furosemide directly causes relaxation in human fetal airway and that delivery of loop diuretics to either the adventitial or epithelial surface of newborn mouse airway results in equivalent relaxati
Autor:
Naomi Fujiwara, Elizabeth K. Tam, Lynn M. Iwamoto, Jodi M. Blaisdell, Kenneth T. Nakamura, Delores M. Gries, Catherine F. T. Uyehara
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 279(5)
This study tested the hypothesis that inhaled nitric oxide (NO) and combined NO and hyperoxia will result in less pulmonary dysfunction and delay onset of respiratory signs compared with hyperoxia-exposed newborn guinea pigs (GPs). GPs were exposed t