Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kenneth T. Miyasaki"'
Publikováno v:
Journal of Leukocyte Biology. 70:130-134
Calprotectin is an abundant cytosolic protein complex of humanneutrophils with in vitro extracellular antimicrobial activity. Studiessuggest that calprotectin may be actively secreted from intact HL-60cells and that it can be translocated to polymorp
Publikováno v:
Oral Microbiology and Immunology. 15:226-231
The bactericidal activity of synthetic LL-37, a cathelicidin, was assessed against Actinobacillus actinomycetemcomitans (three strains) and Capnocytophaga spp. (three strains). All strains were sensitive to LL-37, and exhibited 99% effective dose of
Publikováno v:
Journal of Periodontology. 69:879-883
The purpose of this study was to determine the levels of calprotectin and lactoferrin, 2 microbiostatic proteins, in the gingival crevicular fluid (GCF) of normal children. The children represented a population, primarily underprivileged, seeking car
Autor:
Kenneth T. Miyasaki, Robert I. Lehrer
Publikováno v:
International Journal of Antimicrobial Agents. 9:269-280
Small, cysteine-rich, β-sheet peptide antibiotics are found throughout the Animalia. Though broad spectrum in potential, they may exert selective antimicrobial effects under certain conditions. We have explored the antimicrobial properties of two fa
Publikováno v:
Oral Microbiology and Immunology. 9:186-192
We previously demonstrated that human polymorphonuclear leukocyte (PMN) secretions are capable of activating and inhibiting natural killer cell (NK) cytotoxicity depending on the eliciting PMN stimulus. Serum-opsonized zymosan induced PMN to secrete
Publikováno v:
Journal of Dental Research. 72:517-523
Calprotectin is a complex of two anionic proteins found in abundance in the cytosol of neutrophils, certain macrophages, and oral epithelial keratinocytes. Bacteria of the genus Capnocytophaga are pathogens of periodontal origin which can cause syste
Publikováno v:
Oral Microbiology and Immunology. 7:89-95
We studied the differential effects of polymorphonuclear leukocyte (PMN) secretion on human natural killer cells (NK) and lymphokine-activated killer cell (LAK) activity. Supernatant fluids from PMN stimulated by serum-opsonized zymosan (SOZ), n-form
Publikováno v:
Infection and Immunity. 59:3760-3767
The purpose of this study was to determine whether granule fractions of human neutrophils differentially kill Actinobacillus actinomycetemcomitans and Capnocytophaga spp. Granule extracts were subjected to gel filtration, and seven fractions (designa
Publikováno v:
Analytical Biochemistry. 193:38-44
The human neutrophil lysosomal enzyme, myeloperoxidase (MPO), exists in three major and chromatographically distinct forms, MPO I, MPO II, and MPO III. We used cation-exchange medium-pressure liquid chromatography and kinetic microenzyme assay (or sp
Publikováno v:
Oral Microbiology and Immunology. 5:315-319
Oral, gram-negative, facultative bacteria, including Actinobacillus actinomycetemcomitans, Eikenella corrodens, and Capnocytophaga spp. have been associated with destructive periodontal infection. Neutrophils play a critical role in defending the per