Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Kenneth P. Wheeler"'
Autor:
Kooresh I Shoghi, Jinbin Xu, Yi Su, June He, Douglas Rowland, Ying Yan, Joel R Garbow, Zhude Tu, Lynne A Jones, Ryuji Higashikubo, Kenneth T Wheeler, Ronald A Lubet, Robert H Mach, Ming You
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74188 (2013)
The sigma-2 receptor is expressed in higher density in proliferating (P) tumor cells versus quiescent (Q) tumor cells, thus providing an attractive target for imaging the proliferative status (i.e., P:Q ratio) of solid tumors. Here we evaluate the ut
Externí odkaz:
https://doaj.org/article/c5a3854f8bff403898b8262dcd16b9ea
Autor:
Michael eRobbins, Dana eGreene-Schloesser, Ann M. Peiffer, Edward eShaw, Michael D. Chan, Kenneth T. Wheeler
Publikováno v:
Frontiers in Oncology, Vol 2 (2012)
Approximately 100,000 primary and metastatic brain tumor patients/year in the US survive long enough (> 6 months) to experience radiation-induced brain injury. Prior to 1970, the human brain was thought to be highly radioresistant; the acute CNS synd
Externí odkaz:
https://doaj.org/article/302d8aba7d9d4d6892089926e3b41446
Autor:
Angelo F. Borghetti, Roberta Alfieri, Claudia Fumarola, Domenica Carnicelli, Kenneth P. Wheeler, Giuseppe De Palma, Federica Vacondio, Pier Giorgio Petronini, Mara Bonelli, Maurizio Brigotti, Andrea Cavazzoni, Claudia Silva, Paola Mozzoni, Piero Sestili, Antonio Mutti
Publikováno v:
The Journal of Physiology. 576:391-401
Exposure of C2C12 muscle cells to hypertonic stress induced an increase in cell content of creatine transporter mRNA and of creatine transport activity, which peaked after about 24 h incubation at 0.45 osmol (kg H2O)−1. This induction of transport
Autor:
Pier Giorgio Petronini, Mara Bonelli, Andrea Cavazzoni, Kenneth P. Wheeler, Angelo F. Borghetti, Silvia Desenzani, Roberta Alfieri
Publikováno v:
The Journal of Physiology. 555:757-767
Studies of the responses of porcine pulmonary endothelial cells to acute hypertonic stress have been extended by examining the induction and underlying mechanisms of cell tolerance to both osmotic and heat stresses. Preliminary adaptation of these ce
Autor:
Domenica Carnicelli, Mara Bonelli, Roberta Alfieri, Pier Giorgio Petronini, Angelo F. Borghetti, Maurizio Brigotti, Kenneth P. Wheeler
Publikováno v:
Biochemical Journal. 369:369-374
To mimic what might happen in cells exposed to hypertonicity, the effects of increased osmolarity and ionic strength on cell-free protein synthesis have been examined. Translation of globin mRNA by rabbit reticulocyte lysate decreased by 30-60% when
Autor:
Roberta Alfieri, Andrea Cavazzoni, Mara Bonelli, Kenneth P. Wheeler, Pier Giorgio Petronini, Angelo F. Borghetti, Alessandro E. Caccamo
Publikováno v:
The Journal of Physiology. 540:499-508
Porcine pulmonary arterial endothelial cells accumulated myo-inositol and taurine, as well as betaine, during adaptation to hypertonic stress. The cells grew and maintained their normal morphology during culture in hypertonic (0.5 osmol (kg H(2)O)(-1
Autor:
Angelo F. Borghetti, Mara Bonelli, Alessandro E. Caccamo, Kenneth P. Wheeler, P. G. Petronini, Andrea Cavazzoni, Roberta Alfieri
Publikováno v:
Biochemical and Biophysical Research Communications. 283:174-178
When porcine endothelial cells were exposed to hypertonicity, both the level of ATA2 (amino acid transporter 2) mRNA and activity of amino acid transport System A increased transiently, peaking after about 6 and 9 h, respectively. Cycloheximide, like
Autor:
Andrea Cavazzoni, Silvia Desenzani, Mara Bonelli, Angelo F. Borghetti, Roberta Alfieri, Kenneth P. Wheeler, Pier Giorgio Petronini
Publikováno v:
The Journal of General Physiology
The activity of amino acid transport system A ([Oxender and Christensen, 1963][1]) is regulated in a variety of different ways, the best studied being the increases of its activity caused by starving cells of amino acids or by exposing them to hypert
Publikováno v:
Biochemical Journal. 300:45-50
The osmotically inducible uptake of betaine (NNN-trimethylglycine) by SV-3T3 cells has been studied and compared with the similar process in MDCK cells. Betaine uptake by SV-3T3 cells could be described in terms of a saturable, Na(+)-dependent, compo
Autor:
Kenneth P. Wheeler, E. De Angelis, Cinzia Campanini, P. G. Petronini, R. Alfieri, Angelo F. Borghetti
Publikováno v:
British Journal of Cancer
Responses both to hyperosmotic stress and to heat shock were compared in 3T3 cells, spontaneously transformed cells (ST3T3) and simian virus 40-transformed cells (SV3T3). Cell adaptation to these stresses was measured in terms of surviving cell viabi