Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kenneth P. Tai"'
Autor:
Andre J. Ouellette, Kun Zhao, Ghee Hwee Lai, Kenneth P. Tai, Nathan W. Schmidt, Abhijit Mishra, Gerard C. L. Wong, Karishma Kamdar
Publikováno v:
Journal of Biological Chemistry. 287:21866-21872
The conserved tridisulfide array of the α-defensin family imposes a common triple-stranded β-sheet topology on peptides that may have highly diverse primary structures, resulting in differential outcomes after targeted mutagenesis. In mouse cryptdi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de7e9e3475897d0d890fdd3331eb7718
https://doi.org/10.1074/jbc.m112.358721
https://doi.org/10.1074/jbc.m112.358721
Autor:
Dat Q. Tran, Annie Wong-Beringer, Michael E. Selsted, Karishma Kamdar, Andre J. Ouellette, Jason Yamaki, Valerie V. Le, Patti Tran, Kenneth P. Tai
Publikováno v:
Innate immunity. 21(1)
Antibiotic-resistant bacterial pathogens threaten public health. Because many antibiotics target specific bacterial enzymes or reactions, corresponding genes may mutate under selection and lead to antibiotic resistance. Accordingly, antimicrobials th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511fd842e5fabd2f620edcf039cc8bce
https://pubmed.ncbi.nlm.nih.gov/24345876
https://pubmed.ncbi.nlm.nih.gov/24345876
Autor:
Angie E. Garcia, Kenneth P. Tai, Alexander Shekhtman, Andre J. Ouellette, Julio A. Camarero, Shadakshara S. Puttamadappa
Defensins are antimicrobial peptides that are important in the innate immune defense of mammals. Upon stimulation by bacterial antigens, enteric α-defensins are secreted into the intestinal lumen where they have potent microbicidal activities. Crypt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b31978764e578303fd0546c22abd8a
https://europepmc.org/articles/PMC3236816/
https://europepmc.org/articles/PMC3236816/
Autor:
Angie E. Garcia, Gerard C. L. Wong, Dat Q. Tran, Lori K. Sanders, Michael E. Selsted, Paul B. McCray, Nathan W. Schmidt, Andre J. Ouellette, Abhijit Mishra, Kenneth P. Tai, Ghee Hwee Lai, Matthew A. Davis
Defensins comprise a potent class of membrane disruptive antimicrobial peptides (AMPs) with well-characterized broad spectrum and selective microbicidal effects. By using high-resolution synchrotron small-angle X-ray scattering to investigate interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0745241bc24b6257a32cf9e381cd3566
https://europepmc.org/articles/PMC3090259/
https://europepmc.org/articles/PMC3090259/
Publikováno v:
Methods in enzymology. 492
In the presence of specialized proteins or peptides, a biological membrane can spontaneously restructure itself to allow communication between the intracellular and the extracellular sides. Examples of these proteins include cell-penetrating peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c27a06d4608479a65f37dc2ed05ce58
https://pubmed.ncbi.nlm.nih.gov/21333790
https://pubmed.ncbi.nlm.nih.gov/21333790
In the presence of specialized proteins or peptides, a biological membrane can spontaneously restructure itself to allow communication between the intracellular and the extracellular sides. Examples of these proteins include cell-penetrating peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96cdd85f8ee545e563726dcedc93fd7d
https://doi.org/10.1016/b978-0-12-381268-1.00016-1
https://doi.org/10.1016/b978-0-12-381268-1.00016-1
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d284b69658f9fd42573980b0771f332e
https://doi.org/10.1096/fasebj.24.1_supplement.117.7
https://doi.org/10.1096/fasebj.24.1_supplement.117.7
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 618
Recombinant expression of alpha-defensins can be obtained at efficient levels in Escherichia coli. Amplified alpha-defensin or pro-alpha-defensin coding cDNA sequences are cloned directionally between EcoRI and SalI sites of the pET-28a expression ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f325c420f4ab35e1532841d97689923c
https://pubmed.ncbi.nlm.nih.gov/20094857
https://pubmed.ncbi.nlm.nih.gov/20094857
Expression and Purification of Recombinant α-Defensins and α-Defensin Precursors in Escherichia coli
Publikováno v:
Methods in Molecular Biology ISBN: 9781607615934
Recombinant expression of alpha-defensins can be obtained at efficient levels in Escherichia coli. Amplified alpha-defensin or pro-alpha-defensin coding cDNA sequences are cloned directionally between EcoRI and SalI sites of the pET-28a expression ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46bbcec4218b996e3480648e8bcc509b
https://doi.org/10.1007/978-1-60761-594-1_4
https://doi.org/10.1007/978-1-60761-594-1_4