Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kenneth P. LeClair"'
Autor:
David M. Koelle, Anna Wald, Pramod K. Srivastava, Roman M. Chicz, Stephen A. Monks, Kenneth H. Fife, Daniel L. Levey, Cristina Musselli, Terri Warren, Kenneth P. Leclair
Publikováno v:
Vaccine. 29:8520-8529
HSV-2, the primary causative agent of genital herpes, establishes latency in sensory ganglia and reactivates causing recurrent lesions and viral shedding. Induction or expansion of CD4 + and CD8 + T cell responses are expected to be important for a s
Autor:
John Pappas, Cristina Musselli, Stephen A. Monks, Annie Mo, Aston Liu, Alemseged Truneh, Hong Chen, Daniel L. Levey, Pramod K. Srivastava, Kenneth P. Leclair, Roman M. Chicz
Publikováno v:
Vaccine. 29:8530-8541
Efforts to develop a subunit vaccine against genital herpes have been hampered by lack of knowledge of the protective antigens of HSV-2, the causative agent of the disease. Vaccines based either on selected antigens or attenuated live virus approache
Autor:
Jin Seon Im, James R. Storey, Steven A. Porcelli, Malcolm W. Kennedy, Gurdyal S. Besra, Karl O.A. Yu, Kenneth P. LeClair, Petr A. Illarionov
Publikováno v:
Journal of Biological Chemistry. 279:299-310
CD1 proteins are antigen-presenting molecules that bind foreign and self-lipids and stimulate specific T cell responses. In the current study, we investigated ligand binding by CD1 proteins by developing a fluorescent probe binding approach using sol
Autor:
Virmondes Rodrigues-Júnior, Kurt A. Heldwein, Pamela J. Ovendale, Anthony A. Frank, Vanja Lazarevic, Michael Tovey, Hua Su, N. B. Pefaur, Terry K. Means, Bing Chen, Reiling Liao, Ammini Jeevan, Jessica Ferrante, Michael Reed, Patrick J. Brennan, Kenneth H. Grabstein, Pilar Domenech, Rebecca A. Lines, Kerry Rutter, Amy Bergtold, Martin I. Voskuil, Christopher C. Dascher, Robert N. Husson, Sahadevan Raman, Steven G. Reed, Roberto Badaró, Gilla Kaplan, Karl Drlica, Charles A. Scanga, Bryan W. Jones, Stefanie N. Vogel, Clifton E. Barry, Ian M. Orme, Natalya Serbina, Tao Lu, Gary K. Schoolnik, Robert Barthel, David R. Sherman, Kathryn DeReimer, Liana Tsenova, John R. Murphy, Steven A. Porcelli, Joanne Turner, Yukari C. Manabe, Eunice Y. Tsai, Dirk Wagner, Philip Hopewell, Michael B. Brenner, Marcos Burgos, JoAnne L. Flynn, A. S. Heinzel, Anne E. Goldfeld, David N. McMurray, Toshiko Yamamoto, Thomas C. Terwilliger, John Chan, Andrea M. Cooper, Sherry Freeman, Xiaoling Puyang, Taeksun Song, Kenji Hiromatsu, Mark R. Alderson, Holly Scott, Alla V. Tsytsykova, Rhea N. Coler, Yong-jun Li, Jeanne Magram, Christine L. Hatem, Kendra Bodnar, Luiz E. Bermudez, Yasir A. W. Skeiky, Diana B. Pedral-Sampaio, L. Zhu, Maria I. Harrell, Gui Liu, William R. Bishai, Kristi M. Guinn, William R. Jacobs, Victoria H. Freedman, André Kipnis, David M. Lewinsohn, Stoyan Bardarov, Amy K. Barczak, Kenneth P. LeClair, Matthew J. Fenton, Xiaowei Xiong, Eduardo Martins Netto, Antonio Campos-Neto, Peter M. Small, Todd M. Lasco, Claudia Manca, Deborah A. Lewinsohn, Charles L. Daley
Publikováno v:
Tuberculosis. 82:113-135
Autor:
Cindy Gingrich-Baker, Kenneth P. LeClair, Christopher C. Dascher, Kenji Hiromatsu, Steven A. Porcelli, Michael B. Brenner, Masahiko Sugita, Samuel M. Behar
Publikováno v:
Immunology. 106:159-172
CD1 molecules are cell-surface glycoproteins with strong structural similarities to major histocompatibility complex (MHC) class I molecules, and studies in humans and mice have demonstrated that CD1 proteins perform the unique role of presenting lip
Autor:
Kenneth P. LeClair, Charles P. Hart, Frank H. Ruddle, Thomas H. Roderick, A. Zelent, Lisa Hunihan, John G. Compton, Stephen H. Langley
Publikováno v:
Journal of Experimental Zoology. 263:83-95
We have identified restriction fragment length polymorphisms between Mus musculus and Mus spretus for the Chromosome 15 loci Hox-3, Wnt-1, Krt-2, Rar-g, and Ly-6. We followed the inheritance of these alleles in interspecific genetic test crosses betw
Autor:
Kenji Hiromatsu, Xiaowei Xiong, Gerald F. Watts, Steven A. Porcelli, Christopher C. Dascher, David N. McMurray, Gui Liu, Michael B. Brenner, Kenneth P. LeClair, Caroline Morehouse
Publikováno v:
International immunology. 15(8)
Lipids and glycolipid molecules derived from Mycobacterium tuberculosis can be presented to T cells by CD1 cell-surface molecules in humans. These lipid-specific T cells are cytolytic, secrete pro-inflammatory cytokines and have bactericidal activity
Autor:
Masahiko Sugita, Kenneth P. LeClair, Christopher C. Dascher, Steven A. Porcelli, Stephen T. Furlong, Michael B. Brenner, Kenji Hiromatsu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 169(1)
Group 1 CD1 molecules have been shown to present lipid and glycolipid Ags of mycobacteria to human T cells. However, a suitable animal model for the investigation of this component of antimycobacterial immunity has not yet been established. Previousl
Publikováno v:
Molecular and cellular biology. 10(4)
A cDNA from a B-cell library was previously isolated that encodes a sequence-specific DNA-binding protein with affinities for related sites in a class I major histocompatibility complex (MHC) and kappa immunoglobulin gene enhancers. We report here ap
Autor:
Margot M. Bridgett, Ulrich Hämmerling, Alfred L. M. Bothwell, Francis J. Dumont, Roger G. E. Palfree, Kenneth P. Leclair
Publikováno v:
European Journal of Immunology. 19:1233-1239
The Ly-6 locus contains multiple genes encoding cell surface proteins, two of which, when cross-linked by antibodies, effect antigen-independent activation of T lymphocytes. In this study, cDNA for Ly-6-encoded antigens have been used as probes to ex