Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kenneth P. Huffman"'
Autor:
Kenneth E. Huffman, Long Shan Li, Ryan Carstens, Hyunsil Park, Luc Girard, Kimberley Avila, Shuguang Wei, Rahul Kollipara, Brenda Timmons, Jessica Sudderth, Nawal Bendris, Jiyeon Kim, Pamela Villalobos, Junya Fujimoto, Sandra Schmid, Ralph J. Deberardinis, Ignacio Wistuba, John Heymach, Ralf Kittler, Esra A. Akbay, Bruce Posner, Yuzhuo Wang, Stephen Lam, Steven A. Kliewer, David J. Mangelsdorf, John D. Minna
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The glucocorticoid receptor (GR) is an important anti-cancer target in lymphoid cancers but has been understudied in solid tumors like lung cancer, although glucocorticoids are often given with chemotherapy regimens to mitigate side effects. Here, we
Externí odkaz:
https://doaj.org/article/12a85fec027a43f998070bed490eb234
Autor:
Xu-Dong Wang, Rongkuan Hu, Qing Ding, Trisha K. Savage, Kenneth E. Huffman, Noelle Williams, Melanie H. Cobb, John D. Minna, Jane E. Johnson, Yonghao Yu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Secreted proteins present a rich resource of potential cancer biomarkers. Here, the authors use mass spectrometry to analyze secretome remodeling in pulmonary neuroendocrine lung cancer cell lines and validate potential biomarkers and therapeutic tar
Externí odkaz:
https://doaj.org/article/ab493e2c25ce4d6f9e28ead2e5b28542
Autor:
Camille Tlemsani, Lorinc Pongor, Fathi Elloumi, Luc Girard, Kenneth E. Huffman, Nitin Roper, Sudhir Varma, Augustin Luna, Vinodh N. Rajapakse, Robin Sebastian, Kurt W. Kohn, Julia Krushkal, Mirit I. Aladjem, Beverly A. Teicher, Paul S. Meltzer, William C. Reinhold, John D. Minna, Anish Thomas, Yves Pommier
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108296- (2020)
Summary: CellMiner-SCLC (https://discover.nci.nih.gov/SclcCellMinerCDB/) integrates drug sensitivity and genomic data, including high-resolution methylome and transcriptome from 118 patient-derived small cell lung cancer (SCLC) cell lines, providing
Externí odkaz:
https://doaj.org/article/c3a89008a1ef48f497155a5b22995bc3
Autor:
Mahesh S. Padanad, Georgia Konstantinidou, Niranjan Venkateswaran, Margherita Melegari, Smita Rindhe, Matthew Mitsche, Chendong Yang, Kimberly Batten, Kenneth E. Huffman, Jingwen Liu, Ximing Tang, Jaime Rodriguez-Canales, Neda Kalhor, Jerry W. Shay, John D. Minna, Jeffrey McDonald, Ignacio I. Wistuba, Ralph J. DeBerardinis, Pier Paolo Scaglioni
Publikováno v:
Cell Reports, Vol 16, Iss 6, Pp 1614-1628 (2016)
KRAS is one of the most commonly mutated oncogenes in human cancer. Mutant KRAS aberrantly regulates metabolic networks. However, the contribution of cellular metabolism to mutant KRAS tumorigenesis is not completely understood. We report that mutant
Externí odkaz:
https://doaj.org/article/accd4720f8274f44bb862c81497526a0
Publikováno v:
Frontiers in Endocrinology, Vol 6 (2015)
Uveal melanoma (UM) is recognized as the most common intraocular malignancy and the second most common form of melanoma. Nearly 50% of UM patients develop untreatable and fatal metastases. The 48-member nuclear receptor (NR) superfamily represents a
Externí odkaz:
https://doaj.org/article/d8d00ead2aa14fb788a00e37756405a9
Publikováno v:
Environment and Behavior. 27:153-183
Numerous strategies have been employed to examine ways to reduce the litter problem in society. However, the problem continues. Although the research does rot suggest a single "cure-all" method to eliminate littering behavior, many simple, creative,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c05e3cb2aa74d7b1e840c732847e5531
https://doi.org/10.1177/0013916595272003
https://doi.org/10.1177/0013916595272003