Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kenneth P. Hough"'
Autor:
Shaheer Ahmad, Sierra Single, Yuelong Liu, Kenneth P. Hough, Yong Wang, Victor J. Thannickal, Mohammad Athar, Kayla F. Goliwas, Jessy S. Deshane
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 978 (2024)
Exposure to heavy metals (HMs) is often associated with inflammation and cell death, exacerbating respiratory diseases including asthma. Most inhaled particulate HM exposures result in the deposition of HM-bound fine particulate matter, PM2.5, in pul
Externí odkaz:
https://doaj.org/article/d607257caa89471f9b00c2e471025d23
Autor:
Sultan Tousif, Yong Wang, Joshua Jackson, Kenneth P. Hough, John G. Strenkowski, Mohammad Athar, Victor J. Thannickal, Robert H. McCusker, Selvarangan Ponnazhagan, Jessy S. Deshane
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Regulatory B cells (Breg) are IL-10 producing subsets of B cells that contribute to immunosuppression in the tumor microenvironment (TME). Breg are elevated in patients with lung cancer; however, the mechanisms underlying Breg development and their f
Externí odkaz:
https://doaj.org/article/1942612f213d4139803771b8c0d5424a
Autor:
Kayla F. Goliwas, Hannah M. Ashraf, Anthony M. Wood, Yong Wang, Kenneth P. Hough, Sandeep Bodduluri, Mohammad Athar, Joel L. Berry, Selvarangan Ponnazhagan, Victor J. Thannickal, Jessy S. Deshane
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Tumor-stromal interactions within the tumor microenvironment (TME) influence lung cancer progression and response to therapeutic interventions, yet traditional in vitro studies fail to replicate the complexity of these interactions. Herein, we develo
Externí odkaz:
https://doaj.org/article/90f97a9bf0e049c8b01cac94dcb42e54
Autor:
Kenneth P. Hough, Miranda L. Curtiss, Trevor J. Blain, Rui-Ming Liu, Jennifer Trevor, Jessy S. Deshane, Victor J. Thannickal
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Asthma is an inflammatory disease of the airways that may result from exposure to allergens or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of breath. The structural changes of the airways associated with a
Externí odkaz:
https://doaj.org/article/7ec7050af39f4fa4aba066295cbe8044
Autor:
Kenneth P. Hough, Jennifer L. Trevor, John G. Strenkowski, Yong Wang, Balu K. Chacko, Sultan Tousif, Diptiman Chanda, Chad Steele, Veena B. Antony, Terje Dokland, Xiaosen Ouyang, Jianhua Zhang, Steven R. Duncan, Victor J. Thannickal, Victor M. Darley-Usmar, Jessy S. Deshane
Publikováno v:
Redox Biology, Vol 18, Iss , Pp 54-64 (2018)
Chronic inflammation involving both innate and adaptive immune cells is implicated in the pathogenesis of asthma. Intercellular communication is essential for driving and resolving inflammatory responses in asthma. Emerging studies suggest that extra
Externí odkaz:
https://doaj.org/article/f8e7245e7f7e443e8f97162b871a8929
Autor:
Yong Wang, Derek Van Vessem, Jessy S. Deshane, Kayla F. Goliwas, Selvarangan Ponnazhagan, Sultan Tousif, Paige E. Severino, Hong Wang, Roy P. Koomullil, Kenneth P. Hough, Andra R. Frost, Joel L. Berry
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Breast cancer (BCa) proliferates within a complex, three-dimensional microenvironment amid heterogeneous biochemical and biophysical cues. Understanding how mechanical forces within the tumor microenvironment (TME) regulate BCa phenotype is of great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197226f9938dce9098e8ee9fd922809c
https://doi.org/10.1038/s41374-020-0452-1
https://doi.org/10.1038/s41374-020-0452-1
Autor:
Jessy S. Deshane, Kenneth P. Hough
Publikováno v:
Methods
Exosomes have been described as promising biomarkers for understanding disease progression and prognosis. These lipid membrane nanoparticles derived from airway cells have been shown to have immunomodulatory effects, such as driving inflammatory resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db01c73ec419294de3f4a2cd86069b0f
https://doi.org/10.1016/j.ymeth.2020.01.003
https://doi.org/10.1016/j.ymeth.2020.01.003
Autor:
Jessy S. Deshane, Mohammad Athar, Kayla F. Goliwas, Selvarangan Ponnazhagan, Victor J. Thannickal, Anthony M. Wood, Sandeep Bodduluri, Joel L. Berry, Kenneth P. Hough, Yong Wang, Hannah M Ashraf
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
Tumor-stromal interactions within the tumor microenvironment (TME) influence lung cancer progression and response to therapeutic interventions, yet traditional in vitro studies fail to replicate the complexity of these interactions. Herein, we develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d107ad2a95b72808f77c65f21b42b13
https://doi.org/10.3389/fonc.2021.654922
https://doi.org/10.3389/fonc.2021.654922
Autor:
Jessy S. Deshane, Kenneth P. Hough, Victor J. Thannickal, Miranda L. Curtiss, Rui-Ming Liu, Jennifer Trevor, Trevor J. Blain
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Frontiers in Medicine
Frontiers in Medicine
Asthma is an inflammatory disease of the airways that may result from exposure to allergens or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of breath. The structural changes of the airways associated with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1521e0dc6e9cf4a29eaf2b5e9f94fbe
https://www.frontiersin.org/article/10.3389/fmed.2020.00191/full
https://www.frontiersin.org/article/10.3389/fmed.2020.00191/full
Autor:
Alexandra Pritchard, Victor M. Darley-Usmar, Balu K. Chacko, Jessy S. Deshane, Sultan Tousif, Saad A. Khan, John G. Strenkowski, Yong Wang, Kenneth P. Hough
Publikováno v:
Cells, Vol 9, Iss 1303, p 1303 (2020)
Cells
Volume 9
Issue 5
Cells
Volume 9
Issue 5
Cellular cross-talk within the tumor microenvironment (TME) by exosomes is known to promote tumor progression. Tumor promoting macrophages with an M2 phenotype are suppressors of anti-tumor immunity. However, the impact of tumor-derived exosomes in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fc0404c3d8d221691728f8070a23b4
https://www.mdpi.com/2073-4409/9/5/1303
https://www.mdpi.com/2073-4409/9/5/1303