Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Kenneth P Smith"'
Autor:
Christopher E Morgan, Yoon-Suk Kang, Alex B Green, Kenneth P Smith, Matthew G Dowgiallo, Brandon C Miller, Lucius Chiaraviglio, Katherine A Truelson, Katelyn E Zulauf, Shade Rodriguez, Anthony D Kang, Roman Manetsch, Edward W Yu, James E Kirby
Publikováno v:
PLoS Biology, Vol 21, Iss 5, p e3002091 (2023)
The streptothricin natural product mixture (also known as nourseothricin) was discovered in the early 1940s, generating intense initial interest because of excellent gram-negative activity. Here, we establish the activity spectrum of nourseothricin a
Externí odkaz:
https://doaj.org/article/6b1e987f62164968af737ff75960376a
Autor:
Kenneth C. Smith, Daniel G. Chawla, Bhavjinder K. Dhillon, Zhou Ji, Randi Vita, Eva C. van der Leest, Jing Yi Jessica Weng, Ernest Tang, Amani Abid, The Human Immunology Project Consortium (HIPC), Bjoern Peters, Robert E. W. Hancock, Aris Floratos, Steven H. Kleinstein
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-11 (2022)
Abstract Recent advances in high-throughput experiments and systems biology approaches have resulted in hundreds of publications identifying “immune signatures”. Unfortunately, these are often described within text, figures, or tables in a format
Externí odkaz:
https://doaj.org/article/738fd9d686bc4fa9ae908d01ea059eb9
Changes in phytoplankton and biomineral content of particles during episodic fluxes to abyssal depth
Publikováno v:
Limnology and Oceanography Letters, Vol 7, Iss 4, Pp 342-353 (2022)
Abstract Large episodic pulses of particulate organic carbon (POC) at the deep‐sea (~ 4000 m) time‐series Sta. M in the Northeast Pacific Ocean have increased in frequency and magnitude over the past 32 years. We inferred the ecological drivers o
Externí odkaz:
https://doaj.org/article/5371287e9ebd47189dd9b04cc86fbc27
Publikováno v:
Epilepsia Open, Vol 7, Iss 1, Pp 124-130 (2022)
Abstract Objective Palliative epilepsy surgery via corpus callosotomy (CC) or vagus nerve stimulation (VNS) is commonly employed for drug‐resistant seizures in Lennox‐Gastaut Syndrome (LGS). VNS is less effective at reducing seizures but has fewe
Externí odkaz:
https://doaj.org/article/dfd9aff1a2b947aeab7a5a3604f58ac4
Publikováno v:
BMC Pediatrics, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Multiple clinical prediction rules have been published to risk-stratify febrile infants ≤60 days of age for serious bacterial infections (SBI), which is present in 8-13% of infants. We evaluate the cost-effectiveness of strategi
Externí odkaz:
https://doaj.org/article/3b68764fe1434e12845e7dd5028302b8
Autor:
Lyra O Randzavola, Paige M Mortimer, Emma Garside, Elizabeth R Dufficy, Andrea Schejtman, Georgia Roumelioti, Lu Yu, Mercedes Pardo, Kerstin Spirohn, Charlotte Tolley, Cordelia Brandt, Katherine Harcourt, Esme Nichols, Mike Nahorski, Geoff Woods, James C Williamson, Shreehari Suresh, John M Sowerby, Misaki Matsumoto, Celio XC Santos, Cher Shen Kiar, Subhankar Mukhopadhyay, William M Rae, Gordon J Dougan, John Grainger, Paul J Lehner, Michael A Calderwood, Jyoti Choudhary, Simon Clare, Anneliese Speak, Giorgia Santilli, Alex Bateman, Kenneth GC Smith, Francesca Magnani, David C Thomas
Publikováno v:
eLife, Vol 11 (2022)
EROS (essential for reactive oxygen species) protein is indispensable for expression of gp91phox, the catalytic core of the phagocyte NADPH oxidase. EROS deficiency in humans is a novel cause of the severe immunodeficiency, chronic granulomatous dise
Externí odkaz:
https://doaj.org/article/1b48b81ab31e44d4a2884318ac761009
Autor:
Bonnie G. Waring, Kenneth R. Smith, Michael Belluau, Rim Khlifa, Christian Messier, Alison Munson, Alain Paquette
Publikováno v:
Frontiers in Forests and Global Change, Vol 5 (2022)
The formation and turnover of soil organic carbon (C), the largest terrestrial C pool, is strongly impacted by the ultimate source of that C: leaves, wood, roots, and root exudates. The quantity and quality of these inputs is determined by the identi
Externí odkaz:
https://doaj.org/article/987a2be30e564c56a019e61da09c9adc
Autor:
Benjamin A. Krishna, Eleanor Y. Lim, Lenette Mactavous, Paul A. Lyons, Rainer Doffinger, John R. Bradley, Kenneth G.C. Smith, John Sinclair, Nicholas J. Matheson, Paul J. Lehner, Mark R. Wills, Nyaradzai Sithole
Publikováno v:
EBioMedicine, Vol 81, Iss , Pp 104129- (2022)
Summary: Background: There is currently no consensus on the diagnosis, definition, symptoms, or duration of COVID-19 illness. The diagnostic complexity of Long COVID is compounded in many patients who were or might have been infected with SARS-CoV-2
Externí odkaz:
https://doaj.org/article/b804555307e642b3be053fb996e2b97f
Autor:
Christophe Bourges, Abigail F Groff, Oliver S Burren, Chiara Gerhardinger, Kaia Mattioli, Anna Hutchinson, Theodore Hu, Tanmay Anand, Madeline W Epping, Chris Wallace, Kenneth GC Smith, John L Rinn, James C Lee
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 5, Pp 1-17 (2020)
Abstract Deriving mechanisms of immune‐mediated disease from GWAS data remains a formidable challenge, with attempts to identify causal variants being frequently hampered by strong linkage disequilibrium. To determine whether causal variants could
Externí odkaz:
https://doaj.org/article/6f6d2d05ba2f4f178954073cc994019a
Autor:
Prasanti Kotagiri, Federica Mescia, Aimee L. Hanson, Lorinda Turner, Laura Bergamaschi, Ana Peñalver, Nathan Richoz, Stephen D. Moore, Brian M. Ortmann, Benjamin J. Dunmore, Michael D. Morgan, Zewen Kelvin Tuong, Berthold Göttgens, Mark Toshner, Christoph Hess, Patrick. H. Maxwell, Menna. R. Clatworthy, James A. Nathan, John R. Bradley, Paul A. Lyons, Natalie Burrows, Kenneth G.C. Smith
Publikováno v:
EBioMedicine, Vol 77, Iss , Pp 103878- (2022)
Summary: Background: Prominent early features of COVID-19 include severe, often clinically silent, hypoxia and a pronounced reduction in B cells, the latter important in defence against SARS-CoV-2. This presentation resembles the phenotype of mice wi
Externí odkaz:
https://doaj.org/article/31b2a9439b5b4fe2a7b377dc630c61af