Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Kenneth P Klinker"'
Autor:
Karri A. Bauer, Laura A. Puzniak, Kalvin C. Yu, Kenneth P. Klinker, Janet A. Watts, Pamela A. Moise, Lyn Finelli, Vikas Gupta
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Antibiotic usage and antibiotic resistance (ABR) patterns changed during the COVID-19 pandemic. Inadequate empiric antibiotic therapy (IET) is a significant public health problem and contributes to ABR. We evaluated factors associ
Externí odkaz:
https://doaj.org/article/bd79a4f4ac744a1ab3a466f90d277b7c
Publikováno v:
Clinical Case Reports, Vol 8, Iss 7, Pp 1126-1129 (2020)
Abstract Two patients with normal renal function, yet each showed unexpected, supra‐ and subtherapeutic linezolid plasma concentrations resulting in toxicity and ineffective therapy, respectively. TDM helps to early identify and correct such excurs
Externí odkaz:
https://doaj.org/article/735201c0dadf4046933cbcb8e43d14ee
Autor:
Kenneth P. Klinker, Levita K. Hidayat, C. Andrew DeRyke, Daryl D. DePestel, Mary Motyl, Karri A. Bauer
Publikováno v:
Therapeutic Advances in Infectious Disease, Vol 8 (2021)
The rapid evolution of resistance, particularly among Gram-negative bacteria, requires appropriate identification of patients at risk followed by administration of appropriate empiric antibiotic therapy. A primary tenet of antimicrobial stewardship p
Externí odkaz:
https://doaj.org/article/812fbac324e34437ad7980173a439e12
Autor:
Kenneth P. Klinker, Levita K. Hidayat, Eric Wenzler, Joan-Miquel Balada-Llasat, Mary Motyl, C. Andrew DeRyke, Karri A. Bauer
Publikováno v:
Antibiotics, Vol 11, Iss 5, p 660 (2022)
Antimicrobial resistance is a global public health threat, and gram-negative bacteria, such as Enterobacterales and Pseudomonas aeruginosa, are particularly problematic with difficult-to-treat resistance phenotypes. To reduce morbidity and mortality,
Externí odkaz:
https://doaj.org/article/8c31b56bde1d4b6386b74318a37f5b6c
Autor:
Karri A Bauer, Laura A Puzniak, Kalvin C Yu, Kenneth P Klinker, Janet A Watts, Pamela A Moise, Lyn Finelli, ChinEn Ai, Vikas Gupta
Publikováno v:
Open forum infectious diseases. 9(11)
Background Antibacterial therapy is frequently used in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) without evidence of bacterial infection, prompting concerns about increased antimicrobial resistance (AMR). We evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dad6642803f56ce9031aa114843ed42
https://pubmed.ncbi.nlm.nih.gov/36381612
https://pubmed.ncbi.nlm.nih.gov/36381612
Autor:
Evan J Zasowski, Trang D Trinh, Kimberly C Claeys, Abdalhamid M Lagnf, Sahil Bhatia, Kenneth P Klinker, Michael P Veve, Sandy J Estrada, Scott T Johns, Adam J Sawyer, Vanthida Huang, Brandi LaFrance, Donald P Levine, Keith S Kaye, Susan L Davis, Michael J Rybak
Publikováno v:
Open Forum Infectious Diseases. 9
Background Observational data suggest ceftaroline may be effective for methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection (BSI), but comparative data with standard of care are limited. This analysis compares the outcomes of MRSA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59bbaeced61a030f166de4c05f8fd5ef
https://doi.org/10.1093/ofid/ofab606
https://doi.org/10.1093/ofid/ofab606
Autor:
John M. Allen, Ariel Pomputius, Lolade S Bakare, Lindsey M. Childs-Kean, Kenneth P. Klinker, Anthony M. Casapao
Publikováno v:
Infectious Diseases and Therapy, Vol 8, Iss 4, Pp 671-686 (2019)
Infectious Diseases and Therapy
Infectious Diseases and Therapy
Introduction Methicillin-susceptible Staphylococcus aureus (MSSA) is a common cause of infection in humans. Beta-lactam antibiotics are the preferred agents, with anti-staphylococcal penicillins (ASPs) or the first-generation cephalosporin, cefazolin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a661e8c95e689646c8a9926f454e052c
http://link.springer.com/article/10.1007/s40121-019-00259-4
http://link.springer.com/article/10.1007/s40121-019-00259-4
Autor:
Kartikeya Cherabuddi, Kenneth P. Klinker, Marc H. Scheetz, Veena Venugopalan, Charles A. Peloquin, Michael Neely, Jiajun Liu, Nathaniel J. Rhodes, Mohammad H. Al-Shaer
Publikováno v:
Antimicrob Agents Chemother
Cefepime is commonly used in the intensive care unit (ICU) to treat bacterial infections. The time during which the free cefepime concentration is above the MIC (fT(>MIC)) should be optimized to increase the efficacy of the regimen. We aim to optimiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de3c90b037a05561ccaea10e874bbdc7
https://doi.org/10.1128/aac.00745-20
https://doi.org/10.1128/aac.00745-20
Autor:
Kartikeya Cherabuddi, Nicole M. Iovine, Nathaniel J. Rhodes, Charles A. Peloquin, Jiajun Liu, Yiqing Chen, Natalie Hurst, Marc H. Scheetz, Cara Nys, Kenneth P. Klinker, Maria Bruzzone, Veena Venugopalan, Mohammad H. Al-Shaer
BackgroundThe incidence of cefepime-induced neurotoxicity (CIN) in hospitalized patients is highly variable. Although greater cefepime exposures incite neurotoxicity, data evaluating trough thresholds associated with CIN remains limited. The objectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e462f71cd0b6ee94a77bb0d12f3c689e
https://doi.org/10.1101/2020.08.13.250456
https://doi.org/10.1101/2020.08.13.250456
Early therapeutic monitoring of β-lactams and associated therapy outcomes in critically ill patients
Autor:
Charles A. Peloquin, Veena Venugopalan, Kenneth P. Klinker, Kartikeya Cherabuddi, Mohammad H. Al-Shaer, Eric Rubido
Publikováno v:
The Journal of antimicrobial chemotherapy. 75(12)
Background In the ICU, early and appropriate antimicrobial therapy is important to lower infection-related mortality. Objectives Assess whether achieving early β-lactam free concentration above the MIC 100% of the time (fT>MIC) is associated with po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a13e81aa4a92cfc5f32e11806a8d3c9
https://pubmed.ncbi.nlm.nih.gov/32910809
https://pubmed.ncbi.nlm.nih.gov/32910809