Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Kenneth N. Goldie"'
Autor:
Patrick F. James, Con Dogovski, Renwick C.J. Dobson, Michael F. Bailey, Kenneth N. Goldie, John A. Karas, Denis B. Scanlon, Richard A.J. O’Hair, Matthew A. Perugini
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 7, Pp 1384-1394 (2009)
Human apolipoprotein C-I (apoC-I) is an exchangeable apolipoprotein that binds to lipoprotein particles in vivo. In this study, we employed a LC-MS/MS assay to demonstrate that residues 38–51 of apoC-I are significantly protected from proteolysis i
Externí odkaz:
https://doaj.org/article/89e66b82093245dc8c5ecf64eee803c2
Autor:
Sarah J Piper, Lou Brillault, Rosalba Rothnagel, Tristan I Croll, Joseph K Box, Irene Chassagnon, Sebastian Scherer, Kenneth N Goldie, Sandra A Jones, Femke Schepers, Lauren Hartley-Tassell, Thomas Ve, Jason N Busby, Julie E Dalziel, J Shaun Lott, Ben Hankamer, Henning Stahlberg, Mark R H Hurst, Michael J Landsberg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
YenTcA is the pore-forming and membrane binding subunit of the ABC toxin YenTc, which is produced by the insect pathogen Yersinia entomophaga. Here authors present cryo-EM structures of YenTcA purified from the native source which implicate associate
Externí odkaz:
https://doaj.org/article/22ed524a9e8c453c8589dc7718c89ba1
Autor:
Julika Radecke, Raphaela Seeger, Anna Kádková, Ulrike Laugks, Amin Khosrozadeh, Kenneth N Goldie, Vladan Lučić, Jakob B Sørensen, Benoît Zuber
Publikováno v:
Radecke, Julika; Seeger, Raphaela; Kádková, Anna; Laugks, Ulrike; Khosrozadeh, Mohammadamin; Goldie, Kenneth N; Lučić, Vladan; Sørensen, Jakob B; Zuber, Benoît (2023). Morphofunctional changes at the active zone during synaptic vesicle exocytosis. EMBO reports, 24(5), e55719. Nature Publishing Group 10.15252/embr.202255719
Radecke, J, Seeger, R, Kádková, A, Laugks, U, Khosrozadeh, A, Goldie, K N, Lučić, V, Sørensen, J B & Zuber, B 2023, ' Morphofunctional changes at the active zone during synaptic vesicle exocytosis ', EMBO Reports, vol. 24, no. 5, e55719 . https://doi.org/10.15252/embr.202255719
Radecke, J, Seeger, R, Kádková, A, Laugks, U, Khosrozadeh, A, Goldie, K N, Lučić, V, Sørensen, J B & Zuber, B 2023, ' Morphofunctional changes at the active zone during synaptic vesicle exocytosis ', EMBO Reports, vol. 24, no. 5, e55719 . https://doi.org/10.15252/embr.202255719
Synaptic vesicle (SV) fusion with the plasma membrane (PM) proceeds through intermediate steps that remain poorly resolved. The effect of persistent high or low exocytosis activity on intermediate steps remains unknown. Using spray-mixing plunge-free
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc776fc5e67c959fc226e8b1b46c4fd
https://boris.unibe.ch/179590/1/EMBO_Reports_-_2023_-_Radecke_-_Morphofunctional_changes_at_the_active_zone_during_synaptic_vesicle_exocytosis.pdf
https://boris.unibe.ch/179590/1/EMBO_Reports_-_2023_-_Radecke_-_Morphofunctional_changes_at_the_active_zone_during_synaptic_vesicle_exocytosis.pdf
Autor:
Pu Qian, Alastair T. Gardiner, Ivana Šímová, Katerina Naydenova, Tristan I. Croll, Philip J. Jackson, null Nupur, Miroslav Kloz, Petra Čubáková, Marek Kuzma, Yonghui Zeng, Pablo Castro-Hartmann, Bart van Knippenberg, Kenneth N. Goldie, David Kaftan, Pavel Hrouzek, Jan Hájek, Jon Agirre, C. Alistair Siebert, David Bína, Kasim Sader, Henning Stahlberg, Roman Sobotka, Christopher J. Russo, Tomáš Polívka, C. Neil Hunter, Michal Koblížek
Publikováno v:
Science Advances
Qian, P, Gardiner, A T, Šímová, I, Naydenova, K, Croll, T I, Jackson, P J, Nupur, Kloz, M, Čubáková, P, Kuzma, M, Zeng, Y, Castro-Hartmann, P, van Knippenberg, B, Goldie, K N, Kaftan, D, Hrouzek, P, Hájek, J, Agirre, J, Siebert, C A, Bína, D, Sader, K, Stahlberg, H, Sobotka, R, Russo, C J, Polívka, T, Hunter, C N & Koblížek, M 2022, ' 2.4-Å structure of the double-ring Gemmatimonas phototrophica photosystem ', Science Advances, vol. 8, no. 7, eabk3139 . https://doi.org/10.1126/sciadv.abk3139
Qian, P, Gardiner, A T, Šímová, I, Naydenova, K, Croll, T I, Jackson, P J, Nupur, Kloz, M, Čubáková, P, Kuzma, M, Zeng, Y, Castro-Hartmann, P, van Knippenberg, B, Goldie, K N, Kaftan, D, Hrouzek, P, Hájek, J, Agirre, J, Siebert, C A, Bína, D, Sader, K, Stahlberg, H, Sobotka, R, Russo, C J, Polívka, T, Hunter, C N & Koblížek, M 2022, ' 2.4-Å structure of the double-ring Gemmatimonas phototrophica photosystem ', Science Advances, vol. 8, no. 7, eabk3139 . https://doi.org/10.1126/sciadv.abk3139
Phototrophic Gemmatimonadetes evolved the ability to use solar energy following horizontal transfer of photosynthesis-related genes from an ancient phototrophic proteobacterium. The electron cryo-microscopy structure of the Gemmatimonas phototrophica
Publikováno v:
Journal of Biological Chemistry. 294:2279-2292
Substitution of protium (H) for deuterium (D) strongly affects biological systems. Whereas higher eukaryotes such as plants and mammals hardly survive a deuterium content of > 30%, many microorganisms can grow on fully deuterated media, albeit at red
Autor:
Nikolaus Dietz, Kenneth N. Goldie, Ching-Ju Tsai, Stephan Grzesiek, Ramon Guixà-González, Oliver Hartley, Polina Isaikina, Xavier Deupi, Henning Stahlberg, Gebhard F. X. Schertler, Anne Grahl, Timm Maier, Filip Pamula
The human CC chemokine receptor 5 (CCR5) is a G protein-coupled receptor (GPCR) that plays a major role in inflammation and is involved in the pathology of cancer, HIV, and COVID-19. Despite its significance as a drug target, the activation mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::843ed9171efef0fb6518cb4af265eaa9
https://doi.org/10.1101/2020.11.27.401117
https://doi.org/10.1101/2020.11.27.401117
Autor:
Stefan Geimer, Miroslava Schaffer, Gabriel Aeschlimann, Philipp Erdmann, Kenneth N. Goldie, Paul Guichard, Nikolai Klena, Maeva Le Guennec, Lubomír Kováčik, Anne-Marie Tassin, Hugo van den Hoek, Virginie Hamel, Henning Stahlberg, Benjamin D. Engel
Centrioles are evolutionarily conserved barrels of microtubule triplets that form the core of the centrosome and the base of the cilium. In the proximal region of the centriole, nine microtubule triplets attach to each other via A-C linkers and encir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::164fb6617a911da823328e111388a056
https://doi.org/10.1101/2020.07.21.068882
https://doi.org/10.1101/2020.07.21.068882
Publikováno v:
Science Advances
Autor:
Tim Gruene, Guido H. Clever, Christan Zaubitzer, Sacha De Carlo, Elisabeth Müller, Julian T. C. Wennmacher, Teng Li, Gunther Steinfeld, Ariane Fecteau-Lefebvre, Irene Regeni, Radosav S. Pantelic, Kenneth N. Goldie, Stephan Handschin, Jeroen A. van Bokhoven, Jonas Heidler, Gustavo Santiso-Quiñones, Julian J. Holstein, Eric van Genderen
Publikováno v:
Angewandte Chemie. 130:16551-16555
Autor:
Joka Pipercevic, Henning Stahlberg, Kenneth N. Goldie, Sebastian Hiller, Timm Maier, Ricardo D. Righetto, Roman P. Jakob
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1863:183607
Colicins are bacterial toxins targeting Gram-negative bacteria, including E. coli and related Enterobacteriaceae strains. Some colicins form ion-gated pores in the inner membrane of attacked bacteria that are lethal to their target. Colicin Ia was th