Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kenneth M McCullough"'
Autor:
Jakob Hartmann, Thomas Bajaj, Joy Otten, Claudia Klengel, Tim Ebert, Anne-Kathrin Gellner, Ellen Junglas, Kathrin Hafner, Elmira A. Anderzhanova, Fiona Tang, Galen Missig, Lindsay Rexrode, Daniel T. Trussell, Katelyn X. Li, Max L. Pöhlmann, Sarah Mackert, Thomas M. Geiger, Daniel E. Heinz, Roy Lardenoije, Nina Dedic, Kenneth M. McCullough, Tomasz Próchnicki, Thomas Rhomberg, Silvia Martinelli, Antony Payton, Andrew C. Robinson, Valentin Stein, Eicke Latz, William A. Carlezon, Felix Hausch, Mathias V. Schmidt, Chris Murgatroyd, Sabina Berretta, Torsten Klengel, Harry Pantazopoulos, Kerry J. Ressler, Nils C. Gassen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract High levels of proinflammatory cytokines induce neurotoxicity and catalyze inflammation-driven neurodegeneration, but the specific release mechanisms from microglia remain elusive. Here we show that secretory autophagy (SA), a non-lytic moda
Externí odkaz:
https://doaj.org/article/83209dbad20940cdab3e3f6f4104353f
Autor:
BaDoi N. Phan, Madelyn H. Ray, Xiangning Xue, Chen Fu, Robert J. Fenster, Stephen J. Kohut, Jack Bergman, Suzanne N. Haber, Kenneth M. McCullough, Madeline K. Fish, Jill R. Glausier, Qiao Su, Allison E. Tipton, David A. Lewis, Zachary Freyberg, George C. Tseng, Shelley J. Russek, Yuriy Alekseyev, Kerry J. Ressler, Marianne L. Seney, Andreas R. Pfenning, Ryan W. Logan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract In brain, the striatum is a heterogenous region involved in reward and goal-directed behaviors. Striatal dysfunction is linked to psychiatric disorders, including opioid use disorder (OUD). Striatal subregions are divided based on neuroanato
Externí odkaz:
https://doaj.org/article/82f5489316cf4dc69335f0d491c9b09c
Autor:
Kenneth M. McCullough, Seyma Katrinli, Jakob Hartmann, Adriana Lori, Claudia Klengel, Galen Missig, Torsten Klengel, Nicole A. Langford, Emily L. Newman, Kasey J. Anderson, Alicia K. Smith, F. Ivy Carroll, Kerry J. Ressler, William A. Carlezon
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Exposure to stress triggers biological changes throughout the body. Accumulating evidence indicates that alterations in immune system function are associated with the development of stress-associated illnesses such as major depressive disord
Externí odkaz:
https://doaj.org/article/98da7415c3554e35a9732e7817ea59c7
Autor:
Kenneth M. McCullough, Chris Chatzinakos, Jakob Hartmann, Galen Missig, Rachael L. Neve, Robert J. Fenster, William A. Carlezon, Nikolaos P. Daskalakis, Kerry J. Ressler
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Fear and fear extinction learning are dynamic. These dynamic changes are underlined by transcriptional changes. Here, the authors translationally profiled Crh neurons in the amygdala and and identified relevant gene networks.
Externí odkaz:
https://doaj.org/article/60a85e380ecb4cda8951814f82510f94
Autor:
BaDoi N. Phan, Madelyn H. Ray, Xiangning Xue, Robert J. Fenster, Stephen J. Kohut, Jack Bergman, Suzanne N. Haber, Kenneth M. McCullough, Madeline K. Fish, Jill R. Glausier, Qiao Su, Allison E. Tipton, David A. Lewis, Zachary Freyberg, George C. Tseng, Shelley J. Russek, Yuriy Alekseyev, Kerry J. Ressler, Marianne L. Seney, Andreas R. Pfenning, Ryan W. Logan
The striatum in the brain is involved in various behavioral functions, including reward, and disease processes, such as opioid use disorder (OUD). Further understanding of the role of striatal subregions in reward behaviors and their potential associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbf90a0c33219c0801ee6ce03b721202
https://doi.org/10.1101/2023.05.17.541145
https://doi.org/10.1101/2023.05.17.541145
Autor:
Hao Li, Praneeth Namburi, Jacob M. Olson, Matilde Borio, Mackenzie E. Lemieux, Anna Beyeler, Gwendolyn G. Calhoon, Natsuko Hitora-Imamura, Austin A. Coley, Avraham Libster, Aneesh Bal, Xin Jin, Huan Wang, Caroline Jia, Sourav R. Choudhury, Xi Shi, Ada C. Felix-Ortiz, Verónica de la Fuente, Vanessa P. Barth, Hunter O. King, Ehsan M. Izadmehr, Jasmin S. Revanna, Kanha Batra, Kyle B. Fischer, Laurel R. Keyes, Nancy Padilla-Coreano, Cody A. Siciliano, Kenneth M. McCullough, Romy Wichmann, Kerry J. Ressler, Ila R. Fiete, Feng Zhang, Yulong Li, Kay M. Tye
Publikováno v:
Nature
The ability to associate temporally segregated information and assign positive or negative valence to environmental cues is paramount for survival. Studies have shown that different basolateral amygdala (BLA) projections are potentiated following rew
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80226aa3724c83c7d51bcdb139d886b
https://doi.org/10.1038/s41586-022-04964-y
https://doi.org/10.1038/s41586-022-04964-y
Autor:
Kenneth M. McCullough, Dennis Choi, Jidong Guo, Kelsey Zimmerman, Jordan Walton, Donald G. Rainnie, Kerry J. Ressler
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Activation of Thy-1 expressing neurons in the basolateral amygdala (BLA) has been shown to result in inhibition of fear. Here the authors present a comprehensive workflow to identify genes that are upregulated in this population and can be pharmacolo
Externí odkaz:
https://doaj.org/article/8648cad174914c65a41baa622362e723
Autor:
Jakob Hartmann, Thomas Bajaj, Joy Otten, Claudia Klengel, Anne-Kathrin Gellner, Ellen Junglas, Kathrin Hafner, Elmira A Anderzhanova, Fiona Tang, Galen Missig, Lindsay Rexrode, Katelyn Li, Max L Pöhlmann, Daniel E Heinz, Roy Lardenoije, Nina Dedic, Kenneth M McCullough, Tomasz Próchnicki, Thomas Rhomberg, Silvia Martinelli, Antony Payton, Andrew C. Robinson, Valentin Stein, Eicke Latz, William A Carlezon, Mathias V Schmidt, Chris Murgatroyd, Sabina Berretta, Torsten Klengel, Harry Pantazopoulos, Kerry J Ressler, Nils C Gassen
Publikováno v:
bioRxiv
SummaryHigh levels of proinflammatory cytokines induce neurotoxicity and catalyze inflammation-driven neurodegeneration, but the specific release mechanisms from microglia remain elusive. We demonstrate that secretory autophagy (SA), a non-lytic moda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ecd45553917cdd990d78b46f7a9099
https://europepmc.org/articles/PMC10103985/
https://europepmc.org/articles/PMC10103985/
Autor:
Allison R. Foilb, Elisa M. Taylor-Yeremeeva, Emma L. Fritsch, Caitlin Ravichandran, Kimberly R. Lezak, Galen Missig, Kenneth M. McCullough, William A. Carlezon
Publikováno v:
bioRxiv
Stress produces profound effects on behavior, including persistent alterations in sleep patterns. Here we examined the effects of two prototypical stress peptides, pituitary adenylate cyclase-activating polypeptide (PACAP) and corticotropin-releasing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62499ff3543112052f7e10a452b7c85
https://europepmc.org/articles/PMC10055371/
https://europepmc.org/articles/PMC10055371/
Autor:
Kenneth M. McCullough, Chris Chatzinakos, Jakob Hartmann, Galen Missig, Rachael L. Neve, Robert J. Fenster, William A. Carlezon, Nikolaos P. Daskalakis, Kerry J. Ressler
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/2063f66a87944450a2d725adc682cdb8