Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kenneth M Lassen"'
Autor:
Madeleine M Joullie, Kenneth M Lassen
Publikováno v:
ARKIVOC, Vol 2010, Iss 8, Pp 189-250 (2010)
Externí odkaz:
https://doaj.org/article/2970dab914d54f6ca9234cc0d5af8a25
Publikováno v:
ARKIVOC, Vol 2010, Iss 8, Pp 189-250 (2010)
The presence of carboxamide groups is found in a large array of biologically important compounds. Peptides and proteins play an important role in modern biology. A key step in peptide production is the formation of the peptide bond, which involves am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e07c2e29d002500db22e1f0aaffdcaf
https://doi.org/10.3998/ark.5550190.0011.816
https://doi.org/10.3998/ark.5550190.0011.816
Publikováno v:
The Journal of Organic Chemistry. 75:3027-3036
The syntheses of three tamandarin B analogues are described. The goal of these studies was to prepare material to determine their relative therapeutic index and to gain an oversight as to their potential for clinical applications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cee58cd3bbcc07c13fc9fe0c375c43a
https://doi.org/10.1021/jo100457w
https://doi.org/10.1021/jo100457w
Publikováno v:
Tetrahedron Letters. 51:1635-1638
A reliable, high yielding cyclization protocol for the macrocycle of tamandarin B is presented. This strategy will facilitate the synthesis of side chain analogs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2b58efe2b62891aa90ed75c76a4534
https://doi.org/10.1016/j.tetlet.2009.12.091
https://doi.org/10.1016/j.tetlet.2009.12.091
Publikováno v:
Organic letters. 12(22)
The synthesis of Lys(3) tamandarin M is described. This analogue can be used as a protein affinity ligand to probe the mechanism of action of this unique class of molecules.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab56c387e2123b33cc1259f8eec81b7a
https://pubmed.ncbi.nlm.nih.gov/21033723
https://pubmed.ncbi.nlm.nih.gov/21033723
Publikováno v:
Organic Letters; Nov2010, Vol. 12 Issue 22, p5306-5309, 4p