Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Kenneth Lipson"'
1
Effect of angiogenesis inhibitors on oestrogen-mediated endometrial endothelial cell proliferation in the ovariectomized mouse
Autor: Kenneth Lipson, Bam Bang Heryanto, Peter Rogers
Publikováno v: Scopus-Elsevier
It has been suggested that endometrial angiogenesis in response to the sex steroids oestrogen and progesterone is mediated at a local level via compounds such as vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF) and platelet-d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2906a034565b0b1244a61985409762
https://pubmed.ncbi.nlm.nih.gov/12611597
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2
Hepatocyte growth factor expression in human cancer and therapy with specific inhibitors
Autor: Haddad R, Kenneth Lipson, Cp, Webb
Publikováno v: Scopus-Elsevier
Europe PubMed Central
Hepatocyte growth factor/Scatter Factor (HGF/SF) mediated stimulation of the Met receptor tyrosine kinase results in pleiotropic cellular effects including proliferation, morphogenesis, motility and invasion. In vivo, HGF/SF-Met activation has been s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ce50269b1d055a2cb1eb0ebaf160feb3
https://pubmed.ncbi.nlm.nih.gov/11908677
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3
Identification of substituted 3-[(4,5,6, 7-tetrahydro-1H-indol-2-yl)methylene]-1,3-dihydroindol-2-ones as growth factor receptor inhibitors for VEGF-R2 (Flk-1/KDR), FGF-R1, and PDGF-Rbeta tyrosine kinases
Autor: Kenneth Lipson, Li Sun, Ngoc Tran, Randall E. Schreck, Congxing Liang, Gerald McMahon, Steve Hubbard, Cho Tang, Flora Tang, Yong Zhou
Publikováno v: Journal of medicinal chemistry. 43(14)
A series of new 3-substituted indolin-2-ones containing a tetrahydroindole moiety was developed as specific inhibitors of receptor tyrosine kinases associated with VEGF-R, FGF-R, and PDGF-R growth factor receptors. These compounds were evaluated for
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a82521000747419fd98eb6f05019da7
https://pubmed.ncbi.nlm.nih.gov/10893303
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4
Localization of a cycloheximide-sensitivity response element in the human thymidine kinase gene promoter
Autor: Xia, L., Liang, G., Liu, W. -Z, Yuan, Z. -A, Kenneth Lipson
Publikováno v: Europe PubMed Central
Scopus-Elsevier
In order to localize the segment of the human thymidine kinase (TK) gene promoter that mediates sensitivity of TK mRNA expression to the presence of cycloheximide (CX), a series of promoter truncation mutants was prepared between the 460-base pair (b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e34203bc7d3d739c3746045ff569aa95
https://pubmed.ncbi.nlm.nih.gov/7794808
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5
A potential role for c-jun in cell cycle progression through late G1 and S
Autor: Carter R, Sc, Cosenza, Pena A, Kenneth Lipson, Dr, Soprano, Kj, Soprano
Publikováno v: Europe PubMed Central
When the level of c-jun mRNA was analyzed in WI-38 human fibroblasts exciting short- and long-term quiescence, two peaks of c-jun mRNA accumulation were found. The first occurred one hour after stimulation and lasted three to five hours, whereas the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5e3405d43a65300881a84c3cf37ae7fd
https://pubmed.ncbi.nlm.nih.gov/1900357
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7
Relationship between the affinity and proteolysis of the insulin receptor. Evidence that higher affinity receptors are preferentially degraded
Autor: Kenneth Lipson, Yamada K, Aa, Kolhatkar, Db, Donner
Publikováno v: Europe PubMed Central
125I-Insulin binding to rat liver plasma membranes initiated two processes that occurred with similar time courses: an increase of receptor affinity for hormone and degradation of the Mr 135,000 alpha subunit of the insulin receptor to a fragment of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5be47863e59ae9852a84a27dabc6fc90
https://pubmed.ncbi.nlm.nih.gov/3525554
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8
Indolinone tyrosine kinase inhibitors block Kit activation and growth of small cell lung cancer cells
Autor: Krystal, G. W., Honsawek, S., Kiewlich, D., Liang, C., Vasile, S., Sun, L., Mcmahon, G., Kenneth Lipson
Publikováno v: Europe PubMed Central
Scopus-Elsevier
Six indolinone tyrosine kinase inhibitors were characterized for their ability to inhibit Kit kinase and for their effects on the growth of small cell lung cancer (SCLC) cell lines. All of the six compounds were potent inhibitors of Kit kinase in a b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::76139543057d65149444fddfbc95921d
http://europepmc.org/abstract/med/11325836
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