Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Kenneth L. Audus"'
Autor:
Kenneth L. Audus
Publikováno v:
Journal of Pharmaceutical Sciences. 111:286
Autor:
Kenneth L. Audus
Publikováno v:
Journal of Pharmaceutical Sciences. 111:285
Autor:
Kenneth L. Audus
Publikováno v:
Journal of Pharmaceutical Sciences. 110:987
Autor:
Kenneth L. Audus
Publikováno v:
Journal of Pharmaceutical Sciences. 110:988
Autor:
Soniya Vaidya, Phillip M. Gerk, Kenneth L. Audus, Abner N. Nyandege, Marie V. St-Pierre, Andrei M. Mikheev, Kelly E. Desino, Jashvant D. Unadkat, Anand A. Joshi
Publikováno v:
Pharmaceutical Research. 33:2847-2878
The human placenta fulfills a variety of essential functions during prenatal life. Several ABC transporters are expressed in the human placenta, where they play a role in the transport of endogenous compounds and may protect the fetus from exogenous
Publikováno v:
Peptides. 38:414-417
Dynorphin A 1–17 (Dyn A 1–17) is an endogenous neuropeptide known to act at the kappa opioid receptor; it has been implicated in a number of neurological disorders, including neuropathic pain, stress, depression, and Alzheimer’s and Parkinson
Autor:
Veena Vasandani, Bradley Yops, Erik Rytting, D. Nedra Karunaratne, Kenneth L. Audus, Peter S. Silverstein, Amber M. Young
Publikováno v:
Drug Delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067c928efc86dc090cbadc3bbd185f42
https://doi.org/10.1002/9781118833322.ch7
https://doi.org/10.1002/9781118833322.ch7
Publikováno v:
Journal of Pharmaceutical Sciences. 100:4258-4268
The purpose of this study was to investigate whether changes in the pH of the gastrointestinal tract can directly affect P-glycoprotein (P-gp) function. The effect of changes in extracellular pH on P-gp functionality was examined by testing colchicin
Autor:
Salvatore Guccione, Mary L. Michaelis, Rona R. Ramsay, Rosario Pignatello, Kenneth L. Audus, Sabah Ansar, Livia Basile, Kelly E. Desino
Publikováno v:
Biochemical Pharmacology. 78:1412-1417
A variety of approaches have been taken to improve the brain penetration of pharmaceutical agents. The amphipathic character of a compound can improve its interaction with the lipid bilayer within cell membranes, and as a result improve permeability.
Autor:
Hanumaiah Telikepalli, Douglas R. Powell, Mary L. Michaelis, Emily A. Reiff, Gunda I. Georg, Sabah Ansar, Kelly E. Desino, Kenneth L. Audus, Richard H. Himes
Publikováno v:
Journal of Medicinal Chemistry. 52:7537-7543
Compounds that interact with microtubules, such as paclitaxel, have been shown to possess protective properties against beta-amyloid (Abeta) induced neurodegeneration associated with Alzheimer's disease. In this work, the novel agent (3R,5S,7as)-(3,5