Zobrazeno 1 - 10
of 236
pro vyhledávání: '"Kenneth L, McClain"'
Autor:
Anne S. Reiner, Dana Bossert, Justin J. Buthorn, Allison M. Sigler, Selin Gonen, Deanna Fournier, Kathleen Brewer, Jessica Corkran, Gaurav Goyal, Carl E. Allen, Kenneth L. McClain, Thomas M. Atkinson, Kathleen A. Lynch, Jun J. Mao, Katherine S. Panageas, Eli L. Diamond
Publikováno v:
Haematologica, Vol 108, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/485e7e550a044c4bbbfea08a45ef0cfd
Autor:
Karen Phaik Har Lim, Paul Milne, Michael Poidinger, Kaibo Duan, Howard Lin, Naomi McGovern, Harshal Abhyankar, Daniel Zinn, Thomas M. Burke, Olive S. Eckstein, Rikhia Chakraborty, Amel Sengal, Brooks Scull, Evan Newell, Miriam Merad, Kenneth L. McClain, Tsz-Kwong Man, Florent Ginhoux, Matthew Collin, Carl E. Allen
Publikováno v:
Blood Advances, Vol 4, Iss 1, Pp 87-99 (2020)
Abstract: Langerhans cell histiocytosis (LCH) is a myeloproliferative disorder that is characterized by the inflammatory lesions with pathogenic CD1a+CD207+ dendritic cells (DCs). BRAFV600E and other somatic activating MAPK gene mutations have been i
Externí odkaz:
https://doaj.org/article/c86f478e226541b0bac33e2a435850d6
Autor:
Olive S. Eckstein, M. Brooke Bernhardt, Chelsey G. Hood, Vivekanudeep Karri, Stephen F. Kralik, Kenneth L. McClain
Publikováno v:
Pediatric Hematology and Oncology. :1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4211e29ff8ac9dd04987fec209157a9a
https://doi.org/10.1080/08880018.2022.2137609
https://doi.org/10.1080/08880018.2022.2137609
Autor:
Ashley V Geerlinks, Brooks Scull, Christa Krupski, Ryan Fleischmann, Michael A Pulsipher, Mary Eapen, James A Connelly, Catherine M. Bollard, Sung-Yun Pai, Christine Duncan, Leslie S Kean, K. Scott Baker, Lauri Burroughs, Jeffrey R. Andolina, Shalini Shenoy, Philip Roehrs, Rabi Hanna, Julie-An Talano, Kirk R Schultz, Elizabeth O Stenger, Howard Lin, Adi Zoref-Lorenz, Kenneth L McClain, Michael B. Jordan, Tsz-Kwong Man, Carl E Allen, Rebecca A Marsh
Publikováno v:
Blood Advances.
Overall survival following reduced intensity conditioning (RIC) allogeneic hematopoietic cell transplantation (HCT) using alemtuzumab, fludarabine, and melphalan is favorable in patients transplanted for inborn errors of immunity (IEI), but RIC is as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc180a00ad8c35a4b88702244da92603
https://doi.org/10.1182/bloodadvances.2022009478
https://doi.org/10.1182/bloodadvances.2022009478
Autor:
Emily M. Mace, Carl E. Allen, R. Helen Rouce, Asbjørg Stray-Pedersen, Jordan S. Orange, Shalini N. Jhangiani, Olive S. Eckstein, Kenneth L. McClain, M. Cecilia Poli, Ivan K. Chinn, Hey Chong, Nmazuo W. Ozuah, Jason W. Caldwell, Lisa R. Forbes, Erin C. Peckham-Gregory, Tiphanie P. Vogel, Nader Kim El-Mallawany, Juan C. Aldave-Becerra, Joseph Lubega, Jennifer E. Agrusa, Helen E. Heslop, Zeynep H. Coban-Akdemir, James R. Lupski, Francesco Saettini, Nicholas L. Rider, Stephen Jolles, Natalia S. Chaimowitz, Donna M. Muzny, Richard A. Gibbs, Kala Y. Kamdar, Nitya Gulati
Publikováno v:
J Allergy Clin Immunol
Background Pediatric nonmalignant lymphoproliferative disorders (PLPDs) are clinically and genetically heterogeneous. Long-standing immune dysregulation and lymphoproliferation in children may be life-threatening, and a paucity of data exists to guid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557d325f1c5b9f5ddf4f28929e2c5b8b
https://doi.org/10.1016/j.jaci.2021.07.015
https://doi.org/10.1016/j.jaci.2021.07.015
Autor:
Sarah Scollon, Mohammad K. Eldomery, Jacquelyn Reuther, Frank Y. Lin, Samara L. Potter, Lauren Desrosiers, Kenneth L. McClain, Valeria Smith, Jack Meng‐Fen Su, Rajkumar Venkatramani, Jianhong Hu, Viktoriya Korchina, Neda Zarrin‐Khameh, Richard A. Gibbs, Donna M. Muzny, Christine Eng, Angshumoy Roy, D. Williams Parsons, Sharon E. Plon
Publikováno v:
Pediatric Blood & Cancer. 69
The association of childhood cancer with Lynch syndrome is not established compared with the significant pediatric cancer risk in recessive constitutional mismatch repair deficiency syndrome (CMMRD).We describe the clinical features, germline analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afee874c44dec59f8acff0bc6fb59b3
https://doi.org/10.1002/pbc.29859
https://doi.org/10.1002/pbc.29859
Autor:
Alexandra Tabachnikova, Ilaria Laface, Zoi Karoulia, Poulikos I. Poulikakos, Howard Lin, Alessia Baccarini, Amaia Lujambio, Jenielle Jobson, Markus G. Manz, Guray Akturk, Brian D. Brown, Sacha Gnjatic, Kenneth L. McClain, Anahita Rafiei, Jennifer Picarsic, Miriam Merad, Camille Bigenwald, Jessica Le Berichel, Steven T. Chen, Maria Casanova-Acebes, Carl E. Allen, Harshal Abhyankar, Rikhia Chakraborty, John A. Grout, Jerome Martin, C. Matthias Wilk, Rebecca Mancusi
Publikováno v:
Nature Medicine. 27:851-861
Langerhans cell histiocytosis (LCH) is a potentially fatal condition characterized by granulomatous lesions with characteristic clonal mononuclear phagocytes (MNPs) harboring activating somatic mutations in mitogen-activated protein kinase (MAPK) pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d0495703b99fce0609b3d1c129f700d
https://doi.org/10.1038/s41591-021-01304-x
https://doi.org/10.1038/s41591-021-01304-x
Autor:
Kenneth L. McClain
Publikováno v:
Clinics in Perinatology. 48:167-179
Langerhans cell histiocytosis, Rosai-Dorfman disease, and juvenile xanthogranuloma may present at birth or any time afterward. Some patients have minimal skin or lymph node involvement, but others present with life-threatening pulmonary, hepatic, bon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aaca3258276f6ce9af74563a05c0262
https://doi.org/10.1016/j.clp.2020.11.008
https://doi.org/10.1016/j.clp.2020.11.008
Autor:
Kenneth L. McClain
Publikováno v:
Hematology Am Soc Hematol Educ Program
Langerhans cell histiocytosis (LCH) and Erdheim-Chester disease (ECD) are caused by mutations of the MAPK pathway, most often BRAFV600E, in myeloid dendritic cells that lead to some overlapping and other unique presentations of the two diseases. LCH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d910b975d08e18d9a9436290c1d94331
https://doi.org/10.1182/hematology.2020000159
https://doi.org/10.1182/hematology.2020000159
Autor:
Erin Peckham-Gregory, Priya B Shetty, Howard Lin, Brooks Scull, Erik Ehli, Kenneth L. McClain, Philip J. Lupo, Carl E. Allen, Michael E. Scheurer
Publikováno v:
Blood. 140:3953-3954
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72e8e479d48fa49a5955cddd0e3c390c
https://doi.org/10.1182/blood-2022-170418
https://doi.org/10.1182/blood-2022-170418