Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kenneth K. Sokoll"'
Autor:
Joseph Bteich, Mark J. Ernsting, Mohammed Mohammed, Simon A. McManus, Kenneth K. Sokoll, Robert K. Prud'homme
Publikováno v:
Molecular Pharmaceutics. 14:3998-4007
We report the use of flash nanoprecipitation (FNP) as an efficient and scalable means of producing Cellax nanoparticles. Cellax polymeric conjugates consisting of carboxymethyl cellulose functionalized with PEG and hydrophobic anticancer drugs, such
Autor:
Mark J. Ernsting, Joseph Bteich, Kenneth K. Sokoll, Mohammed Mohammed, Henry B. Lowman, Trevor D. McKee, Mohit Trikha, Taira Kiyota
Publikováno v:
Bioconjugate chemistry. 29(6)
Nanoparticles provide a unique opportunity to explore the benefits of selective distribution and release of cancer therapeutics at sites of disease through varying particle sizes and compositions that exploit the enhanced permeability of tumor-associ
Autor:
David L. Emerson, Kenneth K. Sokoll, Mohammed Mohammed, Henry B. Lowman, Elijus Undzys, Joseph Bteich, Kevin Ou, Bryan Hoang, Mohit Trikha, Shyh-Dar Li, Mark J. Ernsting, Ai Lin Su
Publikováno v:
Cancer Research. 76:1342-1342
Purpose: This study aimed to: (1) evaluate the antitumor efficacy of a controlled release cabazitaxel cellulose nanoparticle (CBZed-Nano) in an orthotopic bone model of docetaxel-resistant LNCaP C4-2B prostate cancer, and (2) confirm the efficacy of
Autor:
J. Michael Chong, Kenneth K. Sokoll
Publikováno v:
Organic Preparations and Procedures International. 25:639-647
Autor:
Kenneth K. Sokoll, J. Michael Chong
Publikováno v:
Tetrahedron Letters. 33:879-882
Asymmetric reduction of 1,3-dihalides derived from glycerol occurs with moderate levels of enantiotopic group differentiation. A concomitant kinetic resolution increases the enantiometric purity of the initial product.
Autor:
Charles Sia, Manfred Windisch, Alan M Walfield, Tseng-Yuan Chang, Chang Yi Wang, Chung Ho Hung, Kenneth K. Sokoll, Birgit Hutter-Paier, Connie L. Finstad, Xin De Fang
Publikováno v:
Vaccine. 25(16)
The UBITh ® AD immunotherapeutic vaccine for Alzheimer’s disease uses an amyloid- (A) immunogen having two designer peptides that have been engineered to elicit anti-N terminal A1–14 antibodies while minimizing potential for the generation of ad
Autor:
Luisa E. Sancen Chaparro, Kenneth K. Sokoll, Remmick So, Fu J. Yan, Barbara C. Vanderhyden, Kenneth Garson, Jaclyn Melinda Chabot, Miranda Gonzalez Aguirre
Publikováno v:
Cancer Research. 72:2907-2907
Background: Liposomes, vesicular structures in the nano - micrometer range, have been widely studied as drug delivery vehicles. Liposomes can self-assemble in aqueous solutions and are normally comprised of lipids organized in concentric bilayers tha
Publikováno v:
Cancer Research. 71:1687-1687
Background: Cancer treatment by conventional chemotherapy is hindered by toxic side effects and the frequent development of multi-drug resistance by cancer cells. Cytotoxic peptides are a promising class of drugs that avoid the shortcomings of conven