Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Kenneth K. Iwata"'
Autor:
Clinton J. Grubbs, Holly L. Nicastro, M. Margaret Juliana, Vernon E. Steele, Ann Bode, Chris Tucker, Stanley C. Gill, Kenneth K. Iwata, Eva Szabo, Ronald A. Lubet
PDF file - 40K, Effect of Erlotinib (6 mg/kg BW/day) on Time of Appearance of Methylnitrosourea- Induced Mammary Cancers in Female Sprague-Dawley Rats.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058748d1312b54471ad27eae7abdb047
https://doi.org/10.1158/1940-6207.22523787.v1
https://doi.org/10.1158/1940-6207.22523787.v1
Autor:
Clinton J. Grubbs, Holly L. Nicastro, M. Margaret Juliana, Vernon E. Steele, Ann Bode, Chris Tucker, Stanley C. Gill, Kenneth K. Iwata, Eva Szabo, Ronald A. Lubet
PDF file - 50K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b233f12128b4729dad891b2d730d797
https://doi.org/10.1158/1940-6207.22523784.v1
https://doi.org/10.1158/1940-6207.22523784.v1
Autor:
Qun-Sheng Ji, Neil W. Gibson, John D. Haley, Kenneth K. Iwata, David Epstein, Mark Miglarese, Jonathan Pachter, Yan Yao, Mathew O'Connor, Eric Brown, Sharon Barr, Mark Mulvihill, Stuart Thomson, Maryland Rosenfeld-Franklin, Alexandra Eyzaguirre, Elizabeth Buck
Supplementary Figures 1-6 from Feedback Mechanisms Promote Cooperativity for Small Molecule Inhibitors of Epidermal and Insulin-Like Growth Factor Receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7ec92813ce2f78c103c78d45e441de
https://doi.org/10.1158/0008-5472.22373438.v1
https://doi.org/10.1158/0008-5472.22373438.v1
Autor:
Qun-Sheng Ji, Neil W. Gibson, John D. Haley, Kenneth K. Iwata, David Epstein, Mark Miglarese, Jonathan Pachter, Yan Yao, Mathew O'Connor, Eric Brown, Sharon Barr, Mark Mulvihill, Stuart Thomson, Maryland Rosenfeld-Franklin, Alexandra Eyzaguirre, Elizabeth Buck
Supplementary Table 1 from Feedback Mechanisms Promote Cooperativity for Small Molecule Inhibitors of Epidermal and Insulin-Like Growth Factor Receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3ecdb7f42194c8fd4475413f56effa
https://doi.org/10.1158/0008-5472.22373432.v1
https://doi.org/10.1158/0008-5472.22373432.v1
Autor:
Qun-Sheng Ji, Neil W. Gibson, John D. Haley, Kenneth K. Iwata, David Epstein, Mark Miglarese, Jonathan Pachter, Yan Yao, Mathew O'Connor, Eric Brown, Sharon Barr, Mark Mulvihill, Stuart Thomson, Maryland Rosenfeld-Franklin, Alexandra Eyzaguirre, Elizabeth Buck
Supplementary Methods from Feedback Mechanisms Promote Cooperativity for Small Molecule Inhibitors of Epidermal and Insulin-Like Growth Factor Receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9b5436c6114fe395eb6c96eaf2aced
https://doi.org/10.1158/0008-5472.22373435.v1
https://doi.org/10.1158/0008-5472.22373435.v1
Autor:
Qun-Sheng Ji, Neil W. Gibson, John D. Haley, Kenneth K. Iwata, David Epstein, Mark Miglarese, Jonathan Pachter, Yan Yao, Mathew O'Connor, Eric Brown, Sharon Barr, Mark Mulvihill, Stuart Thomson, Maryland Rosenfeld-Franklin, Alexandra Eyzaguirre, Elizabeth Buck
Supplementary Figure Legends from Feedback Mechanisms Promote Cooperativity for Small Molecule Inhibitors of Epidermal and Insulin-Like Growth Factor Receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f6fa5f41b4f962721e810c3623ae1c
https://doi.org/10.1158/0008-5472.22373441
https://doi.org/10.1158/0008-5472.22373441
Autor:
Matheus Sewastjanow, Kohei Yamashita, Kenneth K. Iwata, Diarmuid Moran, Dina Elsouda, Melissa Pizzi, Ernesto Rosa Vicentini, Namita Shanbhag, Anh Ta, Rebecca Waters, Deyali Chatterjee, Jaffer Ajani
Publikováno v:
Cancer Research. 83:2141-2141
Introduction: CLDN18.2 is an isoform of CLDN18, a member of the Claudin family of proteins with expression that is highly restricted to the gastric epithelium of normal gastric tissue. In tumor tissue from patients with gastric (G) and gastroesophage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::feeeb8f820d34cefb6460fc7ad064374
https://doi.org/10.1158/1538-7445.am2023-2141
https://doi.org/10.1158/1538-7445.am2023-2141
Autor:
Kenneth K. Iwata, Bret Wacker, Monica M. Mita, Q S-C Chu, K Witt, Leslie Wood, Eric K. Rowinsky, S McCarthy, A. Ricart, Alain C. Mita, Garry Schwartz, M.J.A. de Jonge, Jaap Verweij, Kyriakos P. Papadopoulos, Anthony W. Tolcher, M. Hamilton
Publikováno v:
British Journal of Cancer, 105(7), 938-944. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer
BACKGROUND: To evaluate the anticancer activity of erlotinib in patients with previously treated, advanced non-small cell lung cancer (NSCLC) whose dose is increased to that associated with a maximal level of tolerable skin toxicity (i.e., target ras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::481abfa49e01148b797e2c3145ea45a4
https://doi.org/10.1038/bjc.2011.332
https://doi.org/10.1038/bjc.2011.332
Publikováno v:
Cancer Research. 70:P1-08
The EGFR inhibitors (e.g., Tarceva) have been effective in preventing cancer in multiple animal models, including ER positive breast, head and neck, and urinary bladder cancers. Although Tarceva is less toxic than most classical cytotoxic therapies,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::128c835f108688ad6c1bc5b10ad044b8
https://doi.org/10.1158/0008-5472.sabcs10-p1-08-03
https://doi.org/10.1158/0008-5472.sabcs10-p1-08-03
Publikováno v:
Mount Sinai Journal of Medicine: A Journal of Translational and Personalized Medicine. 77:358-365
Over the past 2 decades, our increased understanding of tumor biology has resulted in the delivery of a new generation of molecularly targeted cancer drugs with greater efficacy and less toxicity. This understanding has also provided pharmaceutical a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31c3dfc2fd49ce402eacbd0294beef94
https://doi.org/10.1002/msj.20195
https://doi.org/10.1002/msj.20195