Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Kenneth K. Chan"'
Autor:
Zhongfa Liu, Yonghua Ling, Kenneth K. Chan, Henry W. Fields, Gary D. Stoner, Peter E. Larsen, Andrew S. Holpuch, Meng Tong, Ping Pei, Matthew P. Larsen, Deric E. Budendorf, Susan R. Mallery
Our oral cancer chemoprevention trial data implied that patient-specific differences in local retention and metabolism of freeze-dried components of black raspberries (BRB) affected therapeutic responsiveness. Subsequent studies have confirmed that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a243f0b54b4f56511bc22e397b6ccf
https://doi.org/10.1158/1940-6207.c.6544029
https://doi.org/10.1158/1940-6207.c.6544029
Autor:
Zhongfa Liu, Yonghua Ling, Kenneth K. Chan, Henry W. Fields, Gary D. Stoner, Peter E. Larsen, Andrew S. Holpuch, Meng Tong, Ping Pei, Matthew P. Larsen, Deric E. Budendorf, Susan R. Mallery
PDF file - 83K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e58d959cb58586ae59ab1812a52df1f
https://doi.org/10.1158/1940-6207.22523979.v1
https://doi.org/10.1158/1940-6207.22523979.v1
Autor:
Guido Marcucci, Ly James Lee, Natarajan Muthusamy, Ramiro Garzon, Robert J. Lee, Michael A. Caligiuri, Clara D. Bloomfield, John C. Byrd, Danilo Perrotti, William Blum, Kenneth K. Chan, Alison R. Walker, Rebecca Klisovic, Alice Mims, Pia Hoellerbauer, Hongyan Wang, Ramasamy Santhanam, Bo Yu, Sebastian Schwind, Xiaomeng Huang
Purpose:miR-29b directly or indirectly targets genes involved in acute myeloid leukemia (AML), namely, DNMTs, CDK6, SP1, KIT, and FLT3. Higher miR-29b pretreatment expression is associated with improved response to decitabine and better outcome in AM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e699f9468c0c703bf0376a453fbc770
https://doi.org/10.1158/1078-0432.c.6521693
https://doi.org/10.1158/1078-0432.c.6521693
Autor:
Guido Marcucci, Ly James Lee, Natarajan Muthusamy, Ramiro Garzon, Robert J. Lee, Michael A. Caligiuri, Clara D. Bloomfield, John C. Byrd, Danilo Perrotti, William Blum, Kenneth K. Chan, Alison R. Walker, Rebecca Klisovic, Alice Mims, Pia Hoellerbauer, Hongyan Wang, Ramasamy Santhanam, Bo Yu, Sebastian Schwind, Xiaomeng Huang
PDF file - 325K, Supplemental Table 1: Particle Size Distribution and Zeta Potential; Supplemental Figure 1: Transferrin receptor (CD71) expression on AML patient blasts; Supplemental Figure 2: miR entrapment efficiency; Supplemental Figure 3: Relati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d07ea159d934b21eb55ef12dd4122f7
https://doi.org/10.1158/1078-0432.22449560.v1
https://doi.org/10.1158/1078-0432.22449560.v1
Autor:
Qianben Wang, Kenneth K. Chan, Steven K. Clinton, Hongyan Chen, Zhong Chen, Jennifer Thomas-Ahner, Ming Chiu, Dayong Wu, Anna Rorick, Chunpeng Zhang, Hongyan Wang
Supplementary Figures 1-3 from CCI-779 Inhibits Cell-Cycle G2–M Progression and Invasion of Castration-Resistant Prostate Cancer via Attenuation of UBE2C Transcription and mRNA Stability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3213396984836da070b2b7c090859ead
https://doi.org/10.1158/0008-5472.22389248
https://doi.org/10.1158/0008-5472.22389248
Autor:
Jianhua Yu, Yong Peng, Lai-Chu Wu, Zhiliang Xie, Youcai Deng, Tiffany Hughes, Shun He, XiaoKui Mo, Ming Chiu, Qi-En Wang, Xiaoming He, Shujun Liu, Michael R Grever, Kenneth K Chan, Zhongfa Liu
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55934 (2013)
Bioactive components from dietary supplements such as curcumin may represent attractive agents for cancer prevention or treatment. DNA methylation plays a critical role in acute myeloid leukemia (AML) development, and presents an excellent target for
Externí odkaz:
https://doaj.org/article/6b1c2963d0264d3c8d44fffd02a4d6cb
Publikováno v:
Biomolecules & Therapeutics
Epigenetic silencing is considered to be a major mechanism for loss of activity in tumor suppressors. Reversal of epigenetic silencing by using inhibitors of DNA methyltransferase (DNMT) or histone deacetylases (HDACs) such as 5-Aza-CdR and FK228 has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb012915aac2caa082f780e21aedb95
https://doi.org/10.4062/biomolther.2018.061
https://doi.org/10.4062/biomolther.2018.061
Autor:
Kenneth K. Chan, Adam Crosland
Publikováno v:
American Journal of Obstetrics and Gynecology. 224:S65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ad6cbaff4391ba051349950e74c9a11
https://doi.org/10.1016/j.ajog.2020.12.094
https://doi.org/10.1016/j.ajog.2020.12.094
Autor:
Adam Crosland, Rachel Newman, Joshua Makhoul, Brad Bosse, Emily Seet, Kenneth K. Chan, Dana Senderoff
Publikováno v:
American Journal of Obstetrics and Gynecology. 222:S670
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d35edfd07d7397a334465b0078d0422
https://doi.org/10.1016/j.ajog.2019.11.1098
https://doi.org/10.1016/j.ajog.2019.11.1098
Autor:
Douglas Sharpnack, Kory J. Engelke, Kenneth K. Chan, Joseph M. Covey, Yogen Saunthararajah, Pramod S. Terse, Yonghua Ling
Publikováno v:
International Journal of Toxicology. 33:75-85
Decitabine (5-aza-2′-deoxycytidine; DAC) in combination with tetrahydrouridine (THU) is a potential oral therapy for sickle cell disease and β-thalassemia. A study was conducted in mice to assess safety of this combination therapy using oral gavag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9142e6e5b70459d9bf5fc33168dc49aa
https://doi.org/10.1177/1091581814524994
https://doi.org/10.1177/1091581814524994