Zobrazeno 1 - 10
of 534
pro vyhledávání: '"Kenneth K Tanabe"'
Autor:
Hexiao Tang, MD, PhD, Eric Abston, MD, PhD, Mozhdeh Sojoodi, PhD, Yongtao Wang, PhD, Derek J. Erstad, MD, Zenan Lin, MD, Bryan C. Fuchs, PhD, Kenneth K. Tanabe, MD, Michael Lanuti, MD
Publikováno v:
JTCVS Open, Vol 18, Iss , Pp 306-321 (2024)
Objective: Previous studies have demonstrated synergistic antitumor effects of angiotensin system inhibition (ASI) combined with cisplatin therapy in pancreatic cancer. This study examines whether or not synergistic antitumor effects occur with combi
Externí odkaz:
https://doaj.org/article/c376e8a0c76e47dba90d2c692f361234
Autor:
Kenneth K. Tanabe, David Zahrieh, Carrie A. Strand, Yujin Hoshida, Thomas J. Flotte, Gary Della’Zanna, Asad Umar, Kenneth D. Chavin, Sean Cleary, Naoto Kubota, Josep M. Llovet, Tushar Patel, Christopher Siegel, Paul J. Limburg
Publikováno v:
Gastro Hep Advances, Vol 3, Iss 3, Pp 426-439 (2024)
Background and Aims: Effective approaches for prevention of hepatocellular carcinoma (HCC) will have a significant impact on HCC-related mortality. There are strong preclinical data and rationale to support targeting epidermal growth factor receptor
Externí odkaz:
https://doaj.org/article/b566872f2fe84a5480b71b71604039a4
Autor:
Lindsay Y King, Kara B Johnson, Hui Zheng, Lan Wei, Thomas Gudewicz, Yujin Hoshida, Kathleen E Corey, Tokunbo Ajayi, Nneka Ufere, Thomas F Baumert, Andrew T Chan, Kenneth K Tanabe, Bryan C Fuchs, Raymond T Chung
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114747 (2014)
Single nucleotide polymorphisms (SNPs) in the epidermal growth factor (EGF, rs4444903), patatin-like phospholipase domain-containing protein 3 (PNPLA3, rs738409) genes, and near the interleukin-28B (IL28B, rs12979860) gene are linked to treatment res
Externí odkaz:
https://doaj.org/article/497ea6c6d0304258b7a004b7cf4c1256
Autor:
Veronica Clavijo Jordan, Mozhdeh Sojoodi, Stuti Shroff, Patricia Gonzalez Pagan, Stephen Cole Barrett, Jeremy Wellen, Kenneth K. Tanabe, Raymond T. Chung, Peter Caravan, Eric M. Gale
Publikováno v:
JHEP Reports, Vol 5, Iss 10, Pp 100850- (2023)
Background & Aims: Many liver diseases are driven by inflammation, but imaging to non-invasively diagnose and quantify liver inflammation has been underdeveloped. The inflammatory liver microenvironment is aberrantly oxidising owing in part to reacti
Externí odkaz:
https://doaj.org/article/44357a5814c241f59e134c50450aa874
Autor:
Mozhdeh Sojoodi, Derek J. Erstad, Stephen C. Barrett, Shadi Salloum, Shijia Zhu, Tongqi Qian, Selene Colon, Eric M. Gale, Veronica Clavijo Jordan, Yongtao Wang, Shen Li, Bahar Ataeinia, Sasan Jalilifiroozinezhad, Michael Lanuti, Lawrence Zukerberg, Peter Caravan, Yujin Hoshida, Raymond T. Chung, Gautam Bhave, Georg M. Lauer, Bryan C. Fuchs, Kenneth K. Tanabe
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 5, Pp 1483-1509 (2022)
Background & Aims: During liver fibrosis, tissue repair mechanisms replace necrotic tissue with highly stabilized extracellular matrix proteins. Extracellular matrix stabilization influences the speed of tissue recovery. Here, we studied the expressi
Externí odkaz:
https://doaj.org/article/6ba526f7c87641729036d4c0c5724ed3
Autor:
Gong Zhang, Yufeng Wang, Bryan C. Fuchs, Wei Guo, David L. Drum, Derek J. Erstad, Baomin Shi, Albert B. DeLeo, Hui Zheng, Lei Cai, Liyuan Zhang, Kenneth K. Tanabe, Xinhui Wang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundSorafenib, a kinase inhibitor, is a standard treatment for advanced hepatocellular carcinoma (HCC) but provides only a limited survival benefit. Disulfiram (DSF), a drug for treating alcoholism and a chelator of copper (Cu), forms a complex
Externí odkaz:
https://doaj.org/article/edfdbb08ad7d4e848639da985e479712
Publikováno v:
Holland‐Frei Cancer Medicine. :1-12
Autor:
Derek J. Erstad, Christian T. Farrar, Sarani Ghoshal, Ricard Masia, Diego S. Ferreira, Yin‐Ching Iris Chen, Ji‐Kyung Choi, Lan Wei, Phillip A. Waghorn, Nicholas J. Rotile, Chuantao Tu, Katherine A. Graham‐O'Regan, Mozhdeh Sojoodi, Shen Li, Yang Li, Guogiang Wang, Kathleen E. Corey, Yat Sun Or, Lijuan Jiang, Kenneth K. Tanabe, Peter Caravan, Bryan C. Fuchs
Publikováno v:
Hepatology Communications, Vol 2, Iss 7, Pp 821-835 (2018)
We examined a novel farnesoid X receptor agonist, EDP‐305, for its antifibrotic effect in bile duct ligation (BDL) and choline‐deficient, L‐amino acid‐defined, high‐fat diet (CDAHFD) models of hepatic injury. We used molecular magnetic reso
Externí odkaz:
https://doaj.org/article/3b4760b0fefd4d1697564907fb1c9f1f
Autor:
Noor Jailkhani, Karl R. Clauser, Howard H. Mak, Steffen Rickelt, Chenxi Tian, Charles A. Whittaker, Kenneth K. Tanabe, Stephen R. Purdy, Steven A. Carr, Richard O. Hynes
Publikováno v:
Cancer Research.
Metastases are hard to detect and treat, and they cause most cancer-related deaths. The relative lack of therapies targeting metastases represents a major unmet clinical need. The extracellular matrix (ECM) forms a major component of the tumor microe
Autor:
Juanye Zhang, Yingying Ning, Hua Zhu, Nicholas J. Rotile, He Wei, Himashinie Diyabalanage, Eric C. Hansen, Iris Y. Zhou, Stephen C. Barrett, Mozhdeh Sojoodi, Kenneth K. Tanabe, Valerie Humblet, Alan Jasanoff, Peter Caravan, Moungi G. Bawendi
Publikováno v:
Proceedings of the National Academy of Sciences. 120
SNIO–CBP, a single-nanometer iron oxide (SNIO) nanoparticle functionalized with a type I collagen-binding peptide (CBP), was developed as a T 1 -weighted MRI contrast agent with only endogenous elements for fast and noninvasive detection of liver f