Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Kenneth K, Ng"'
Autor:
Hannah J. Perrin, Kevin W. Currin, Swarooparani Vadlamudi, Gautam K. Pandey, Kenneth K. Ng, Martin Wabitsch, Markku Laakso, Michael I. Love, Karen L. Mohlke
Publikováno v:
PLoS Genetics, Vol 17, Iss 10 (2021)
Chromatin accessibility and gene expression in relevant cell contexts can guide identification of regulatory elements and mechanisms at genome-wide association study (GWAS) loci. To identify regulatory elements that display differential activity acro
Externí odkaz:
https://doaj.org/article/18b6484704474b5f9bc3936b6a808459
Autor:
Andrew J. Plodkowski, Daniel C. McFarland, Miguel A. Villalona-Calero, Mark G. Kris, John J. Fiore, Juliana Eng, Rachel Kim, Ai Ni, Afsheen Iqbal, Charles M. Rudin, Philip Jonsson, Paul K. Paik, Mark T.A. Donoghue, Linda Ahn, Kenneth K. Ng
Publikováno v:
Clin Cancer Res
Purpose: Gemcitabine and albumin-bound paclitaxel (ABP) exhibit synergistic antitumor efficacy, with ABP serving to increase the intratumoral gemcitabine concentration. Both drugs are active in squamous cell lung cancers (SQCLC) and are conventional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ece99738f4a657f46057eecdd6cfca
https://doi.org/10.1158/1078-0432.ccr-19-3060
https://doi.org/10.1158/1078-0432.ccr-19-3060
Autor:
Justin Jee, Emily S. Lebow, Randy Yeh, Jeeban P. Das, Azadeh Namakydoust, Paul K. Paik, Jamie E. Chaft, Gowtham Jayakumaran, A. Rose Brannon, Ryma Benayed, Ahmet Zehir, Mark Donoghue, Nikolaus Schultz, Debyani Chakravarty, Ritika Kundra, Ramyasree Madupuri, Yonina R. Murciano-Goroff, Hai-Yan Tu, Chong-Rui Xu, Andrés Martinez, Clare Wilhelm, Jesse Galle, Bobby Daly, Helena A. Yu, Michael Offin, Matthew D. Hellmann, Piro Lito, Kathryn C. Arbour, Marjorie G. Zauderer, Mark G. Kris, Kenneth K. Ng, Juliana Eng, Isabel Preeshagul, W. Victoria Lai, John J. Fiore, Afsheen Iqbal, Daniela Molena, Gaetano Rocco, Bernard J. Park, Lee P. Lim, Mark Li, Candace Tong-Li, Madhawa De Silva, David L. Chan, Connie I. Diakos, Malinda Itchins, Stephen Clarke, Nick Pavlakis, Adrian Lee, Natasha Rekhtman, Jason Chang, William D. Travis, Gregory J. Riely, David B. Solit, Mithat Gonen, Valerie W. Rusch, Andreas Rimner, Daniel Gomez, Alexander Drilon, Howard I. Scher, Sohrab P. Shah, Michael F. Berger, Maria E. Arcila, Marc Ladanyi, Ross L. Levine, Ronglai Shen, Pedram Razavi, Jorge S. Reis-Filho, David R. Jones, Charles M. Rudin, James M. Isbell, Bob T. Li
Publikováno v:
Nature medicine. 28(11)
Circulating tumor DNA (ctDNA) sequencing guides therapy decisions but has been studied mostly in small cohorts without sufficient follow-up to determine its influence on overall survival. We prospectively followed an international cohort of 1,127 pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d276500cbe7b30ce520bac26d2b720cf
https://pubmed.ncbi.nlm.nih.gov/36357679
https://pubmed.ncbi.nlm.nih.gov/36357679
Publikováno v:
Angewandte Chemie. 128:10157-10161
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::946f29e914faf78596cf9ae4354a7b2d
https://doi.org/10.1002/ange.201605241
https://doi.org/10.1002/ange.201605241
Autor:
Liyang Cui, Juan Chen, Richard Cisek, Gang Zheng, Danielle Tokarz, Virginijus Barzda, Kenneth K. Ng, Fan Wang
Publikováno v:
Angewandte Chemie. 127:14134-14138
Nonlinear optical microscopy has become a powerful tool for high-resolution imaging of cellular and subcellular composition, morphology, and interactions because of its high spatial resolution, deep penetration, and low photo-damage to tissue. Develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d3f3aae369688199055d9ddb490960
https://doi.org/10.1002/ange.201506171
https://doi.org/10.1002/ange.201506171
Publikováno v:
Bioconjugate Chemistry. 26:345-351
Porphysomes are highly quenched unilamellar porphyrin-lipid nanovesicles with structurally dependent photothermal properties. The high packing density of porphyrin molecules in the lipid bilayer enables their application in photothermal therapy, wher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d912733f5b9733292eca8d4e11faf5
https://doi.org/10.1021/bc500595d
https://doi.org/10.1021/bc500595d
Autor:
Robert A. Weersink, Gang Zheng, Brian C. Wilson, Kenneth K. Ng, Elizabeth Huynh, Mojdeh Shakiba, Áron Roxin
Publikováno v:
ACS Nano. 8:8363-8373
Photoacoustic imaging provides high-resolution images at depths beyond the optical diffusion limit. To broaden its utility, there is need for molecular sensors capable of detecting environmental stimuli through alterations in photoacoustic signal. Ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5616b1c04ef967bccef5768bd1ab12c
https://doi.org/10.1021/nn502858b
https://doi.org/10.1021/nn502858b
Publikováno v:
Pharmaceutical Research. 31:1438-1449
Molecular therapeutics often require an effective nanoparticle-based delivery strategy to transport them to cytosolic organelles to be functional. Recently, a cytosolic delivery strategy based on the scavenger receptor class B type I (SR-BI) mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af09a60c919bc33eeb84a426b83c427c
https://doi.org/10.1007/s11095-013-1046-z
https://doi.org/10.1007/s11095-013-1046-z
Publikováno v:
Angewandte Chemie (International ed. in English). 55(34)
Photothermal therapy (PTT) is enhanced by the use of nanoparticles with a large optical absorption at the treatment wavelength. However, this comes at the cost of higher light attenuation that results in reduced depth of heating as well as larger the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6035fa0904905e0e1f69cc4a9476375f
https://pubmed.ncbi.nlm.nih.gov/27411830
https://pubmed.ncbi.nlm.nih.gov/27411830
Publikováno v:
ACS nano. 10(4)
Chlorosomes are vesicular light-harvesting organelles found in photosynthetic green sulfur bacteria. These organisms thrive in low photon flux environments due to the most efficient light-to-chemical energy conversion, promoted by a protein-less asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b362ca1938797822d23773cbf727a17
https://pubmed.ncbi.nlm.nih.gov/27015124
https://pubmed.ncbi.nlm.nih.gov/27015124