Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kenneth John O'Byrne"'
Autor:
Jacob Andrew Tickner, Aaron James Urquhart, Sally-Anne eStephenson, Derek John Richard, Kenneth John O'Byrne
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
The role of exosomes in cancer development has become the focus of much research, due to the many emerging roles possessed by these microscopic messengers. Exosomes are ubiquitously released in to the extracellular milieu, and have been found to regu
Externí odkaz:
https://doaj.org/article/d4bd37b6ab594ca9a8a6a911bae0ecc7
Autor:
Christian Robert Jekimovs, Emma eBolderson, Amila eSuraweera, Mark eAdams, Kenneth John O'Byrne, Derek John Richard
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
The repair of DNA double-strand breaks is a critical cellular mechanism that exists to ensure genomic stability. DNA double-strand breaks are the most deleterious type of insult to a cells genetic material and can lead to genomic instability, apoptos
Externí odkaz:
https://doaj.org/article/cc860a5e75e0467dba2ef6eba4ab136d
Autor:
Julie R. Brahmer, Jong-Seok Lee, Tudor-Eliade Ciuleanu, Reyes Bernabe Caro, Makoto Nishio, Lazlo Urban, Clarisse Audigier-Valette, Lorena Lupinacci, Randeep S. Sangha, Luis G. Paz-Ares, Martin Reck, Hossein Borghaei, Kenneth John O'Byrne, Ravi Gupta, Judith Bushong, Li Li, Steven I. Blum, Laura Eccles, Suresh S. Ramalingam
Publikováno v:
Journal of Clinical Oncology. 40:LBA9025-LBA9025
LBA9025 Background: In CheckMate 227 part 1 (NCT02477826), 1L NIVO + IPI demonstrated long-term, durable survival benefit vs platinum-doublet chemo in patients (pts) with metastatic NSCLC regardless of tumor programmed death ligand 1 (PD-L1) expressi
Autor:
Kenneth John O'Byrne, James Monkman, Honesty Kim, Marie Cumberbatch, Milan Bhagat, Rahul Ladwa, Mark N Adams, Arutha Kulasinghe
Publikováno v:
Journal of Clinical Oncology. 40:8544-8544
8544 Background: Immune checkpoint inhibitors (ICI) have shown durable benefit in a subset of non-small cell lung cancer (NSCLC) patients. The composition of the tumour microenvironment (TME) is becomingly increasingly recognised as an important fact
Publikováno v:
Journal of Clinical Oncology. 40:e15039-e15039
e15039 Background: Next generation sequencing (NGS) technologies are increasingly employed to deliver optimal precision therapy for patients with cancer. The Molecular Screening and Therapeutics (MoST) study led by Prof David Thomas, Garvan Institute
Autor:
Jonathan Charles, Goddard, Christopher Derek, Sutton, Peter N, Furness, Roger Clive, Kockelbergh, Kenneth John, O'Byrne
Publikováno v:
Angiogenesis. 5(1-2)
Microvessel density (MVD) is a widely used surrogate measure of angiogenesis in pathological specimens and tumour models. Measurement of MVD can be achieved by several methods. Automation of counting methods aims to increase the speed, reliability an
Autor:
Jonathan Charles Goddard, Christopher Derek Sutton, Peter N. Furness, Roger Clive Kockelbergh, Kenneth John O'Byrne
Publikováno v:
Angiogenesis; 2002, Vol. 5 Issue 1/2, p15-20, 6p