Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Kenneth J. Sufka"'
Publikováno v:
Cannabis and Cannabinoid Research. 7:804-813
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96e4c5cdc4a9fbd5e87c31a32881571
https://doi.org/10.1089/can.2021.0050
https://doi.org/10.1089/can.2021.0050
Autor:
Hayley M. Schrock, Thomas E. Prisinzano, Kevin B. Freeman, Kenneth J. Sufka, Bruce E. Blough, C. Austin Zamarripa, Tanya Pareek
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Triazole 1.1 is a novel kappa-opioid receptor (KOR) agonist reported to produce antinociception without KOR-typical adverse effects. When combined with the mu-opioid receptor (MOR) agonist, oxycodone, triazole 1.1 blocks oxycodone-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ae9f35c0523136028369645ad93dd4
https://doi.org/10.1007/s00213-021-05965-x
https://doi.org/10.1007/s00213-021-05965-x
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103362 (2014)
Most pre-clinical analgesic efficacy assays still involve nociceptive testing in rodents. This is despite concerns as to the relevance of these tests for evaluating the pain-preventative properties of drugs. More appropriate methods would target pain
Externí odkaz:
https://doaj.org/article/bc891cae1b00457dabe00d12e11e012c
Publikováno v:
Med Cannabis Cannabinoids
Objective: This research examined whether a cannabidiol (CBD)-opioid pharmacotherapy could attenuate cisplatin-induced tactile allodynia. Methods: Mice (C57BL/6) were given 6 doses of 2.3 mg/kg cisplatin intraperitoneally (IP) on alternating days to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5e18000945c282c63b75c9fd986af6e
https://doi.org/10.1159/000489077
https://doi.org/10.1159/000489077
Publikováno v:
Planta Medica. 84:221-224
This study sought to determine whether the cannabis constituent cannabidiol attenuates the development of morphine reward in the conditioned place preference paradigm. Separate groups of mice received either saline or morphine in combination with one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b008729060f812f2ab93addf3958099e
https://doi.org/10.1055/s-0043-117838
https://doi.org/10.1055/s-0043-117838
Autor:
Jessica M. Carpenter, Jonathan R. Black, Hannah M. Harris, Kenneth J. Sufka, Todd A. Smitherman
Publikováno v:
Journal of Neuroscience Methods. 284:63-70
Background Rodent models typically use a single nitroglycerin injection to induce migraine, yet migraine in clinical populations presents as recurrent episodes. Further, these models quantify behavioral endpoints that do not align with the clinical f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d67a609022e676004443b384f133337
https://doi.org/10.1016/j.jneumeth.2017.04.010
https://doi.org/10.1016/j.jneumeth.2017.04.010
Autor:
Hina N. Qureshi, Kenneth J. Sufka, Jussara M. do Carmo, Coco N. Kapanda, Hunter W. McLendon, Fernanda S. da Silva, John E. Hall, S. Stevens Negus, Jennifer E. Naylor, E. Andrew Townsend, Kevin B. Freeman, Shelley R. Edwards, Christopher R. McCurdy
Publikováno v:
Psychopharmacology. 234:2597-2605
Strategies to reduce the misuse of mu opioid agonists are critically needed. Previous work has shown that kappa opioid agonists can diminish the abuse-related effects and augment the antinociceptive effects of mu agonists. However, use of traditional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821ca7c0f843f4d18e96eabdc6e182ef
https://doi.org/10.1007/s00213-017-4652-3
https://doi.org/10.1007/s00213-017-4652-3
Autor:
Mahmoud A. ElSohly, Hannah M. Harris, Amira S. Wanas, Sylvia Caldwell, Kenneth J. Sufka, Mohamed M. Radwan, Margaret A Rousseau
Publikováno v:
Cannabis Cannabinoid Res
Introduction: Cannabis sativa has been used for centuries in treating pain. However, the analgesic role of many of its constituents including terpenes is unknown. This research examined the contributions of terpenes (volatile oil) and cannabinoids in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b1eef52695ecfe1385d9a436957d71
https://europepmc.org/articles/PMC6757239/
https://europepmc.org/articles/PMC6757239/
Autor:
Ikhlas A. Khan, Helaina K. Craig, Jessica M. Carpenter, Catherine A. Criddle, Kenneth J. Sufka, Zulfiqar Ali, Zhihao Zhang
Publikováno v:
Fitoterapia. 109:87-90
This study sought to compare the effects of Mitragyna speciosa (Korth.) Havil. extract, alkaloids fraction, and mitragynine, a μ-opioid receptor agonist, to that of morphine and oxycodone in a test of thermal nociception. In Experiment 1, male Sprag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d1bef0c6905080d9d7b0873fe31ed0
https://doi.org/10.1016/j.fitote.2015.12.001
https://doi.org/10.1016/j.fitote.2015.12.001