Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kenneth J. Murfitt"'
Autor:
Erik M. Jorgensen, Vadivel Ganapathy, Guoliang Jiang, Kenneth J. Murfitt, Aude S. Peden, Eric A. Miska, Julian L. Griffin, You Jun Fei, Patrick Mac, Cecilia Castro
Publikováno v:
Nature neuroscience
Prior to the advent of synthetic nematocides, natural products such as seaweed were used to control nematode infestations. The nematocidal agent in seaweed is betaine, an amino acid that functions as an osmolyte and methyl donor. However, the molecul
LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans
Autor:
Eric A. Miska, Nicolas J. Lehrbach, Anthony Bugaut, Kenneth J. Murfitt, Helen L. Lightfoot, Javier Armisen, Shankar Balasubramanian
Publikováno v:
Nature structural & molecular biology
Developmental expression of the microRNA let-7 is tightly regulated in many animals, and turnover has been linked to LIN-28 and uridylation in mammals. This regulation is now shown to be conserved in Caenorhabditis elegans, and PUP-2 is shown to be a
Autor:
Eric A. Miska, Nicolas J. Lehrbach, Julian L. Griffin, Kenneth J. Murfitt, Cecilia Castro, Cei Abreu-Goodger
Publikováno v:
RNA (New York, N.Y.). 18(12)
Regulation of gene expression by microRNAs (miRNAs) is essential for normal development, but the roles of miRNAs in the physiology of adult animals are poorly understood. We have isolated a conditional allele of DGCR8/pash-1, which allows reversible
Autor:
Kenneth J. Murfitt, Adam Lewis Salt Lake City Bermange, Peter W. Reddien, Alejandro Sánchez Alvarado, Joya R. Jennings
Publikováno v:
Developmental cell. 8(5)
SummaryPlanarians have been a classic model system for the study of regeneration, tissue homeostasis, and stem cell biology for over a century, but they have not historically been accessible to extensive genetic manipulation. Here we utilize RNA-medi
Erratum: Betaine acts on a ligand-gated ion channel in the nervous system of the nematode C. elegans
Autor:
Patrick Mac, You Jun Fei, Kenneth J. Murfitt, Erik M. Jorgensen, Julian L. Griffin, Aude S. Peden, Guoliang Jiang, Vadivel Ganapathy, Cecilia Castro, Eric A. Miska
Publikováno v:
Nature Neuroscience. 17:1840-1840