Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Kenneth J. McRae"'
3
Pilot-Scale Production of Dimethyl 1,4-Cubanedicarboxylate
Autor: Michael J. Falkiner, John Tsanaktsidis, Stuart W. Littler, G. Paul Savage, Kenneth J. McRae
Publikováno v: Organic Process Research & Development. 17:1503-1509
A scalable process for the preparation of high purity dimethyl 1,4-cubanedicarboxylate (3) is reported. The work described herein builds on previous synthetic work from this and other laboratories, to provide a reliable process that can be used to pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d57ae1ee78682b0beb79d8f47bb879a
https://doi.org/10.1021/op400181g
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5
Enantioselective Synthesis of Oasomycin A, Part III: Fragment Assembly and Confirmation of Structure
Autor: Dominic J. Reynolds, David A. Evans, Louis Sebastian Sonntag, Kenneth J. McRae, Pavel Nagorny, Filisaty Vounatsos
Publikováno v: Angewandte Chemie International Edition. 46:545-548
Herein we address the total synthesis of the natural product oasomycin A by assembly of the C1–C12, C13–C28, and C29–C46 subunits, whose syntheses have been described in the preceding Communications. The synthesis plan (Scheme 1) incorporates a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8563f71da4d23e77895fbc3607fab5f8
https://doi.org/10.1002/anie.200603652
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8
Chemoenzymatic methods for the enantioselective preparation of sesquiterpenoid natural products from aromatic precursors
Autor: Martin G. Banwell, Katrina A. Jolliffe, Malcolm D. McLeod, Alison J. Edwards, Kenneth J. McRae, Markus Vögtle, Gwion J. Harfoot, Scott G. Stewart
Publikováno v: Pure and Applied Chemistry. 75:223-229
The enantiomerically pure cis-1,2-dihydrocatechols 2, which are generated by enzymatic dihydroxylation of the corresponding aromatic, engage in regio- and stereo-controlled Diels-Alder cycloaddition reactions to give a range of synthetically useful b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590c292d7302fe8cd390eb164c8bf450
https://doi.org/10.1351/pac200375020223
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9
A chemoenzymatic synthesis of the 12-membered macrolide (–)-cladospolide A
Autor: Katrina A. Jolliffe, Filisaty Vounatsos, Kenneth J. McRae, David T. J. Loong, Martin G. Banwell
Publikováno v: Journal of the Chemical Society, Perkin Transactions 1. :22-25
The enantiomerically pure cis-1,2-dihydrocatechol 7, which is obtained by microbial oxidation of chlorobenzene, has been converted, via a sequence of reactions including ring-closing metathesis and Yamaguchi lactonisation steps, into the natural prod
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7fb1afee4ffc5b0fbd4c9390cdd8f46d
https://doi.org/10.1039/b110018a
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10
Total Synthesis of the Epidermal Growth Factor Inhibitor (−)-Reveromycin B
Autor: Kenneth J. McRae, Anthony N. Cuzzupe, Michael J. Lilly, Mark A. Rizzacasa, Robert K. Mann, Steven C. Zammit, Craig A. Hutton
Publikováno v: The Journal of Organic Chemistry. 66:2382-2393
The total synthesis of the epidermal growth factor inhibitor reveromycin B (2) in 25 linear steps from chiral methylene pyran 13 is described. The key steps involved an inverse electron demand hetero-Diels-Alder reaction between dienophile 13 and die
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca66b42cc10dbedf72f8cc51123affdc
https://doi.org/10.1021/jo001646c
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