Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Kenneth J. Kemphues"'
Autor:
Song Eun Lee, Aiko Sada, Meng Zhang, David J. McDermitt, Shu Yang Lu, Kenneth J. Kemphues, Tudorita Tumbar
Publikováno v:
Cell Reports, Vol 6, Iss 3, Pp 499-513 (2014)
Quiescent hair follicle (HF) bulge stem cells (SCs) differentiate to early progenitor (EP) hair germ (HG) cells, which divide to produce transit-amplifying matrix cells. EPs can revert to SCs upon injury, but whether this dedifferentiation occurs in
Externí odkaz:
https://doaj.org/article/ee2d713c328d4ca182555c7a4e5643d4
Publikováno v:
Journal of Biological Chemistry. 293:610-622
Biotin is an essential cofactor for multiple metabolic reactions catalyzed by carboxylases. Biotin is covalently linked to apoproteins by holocarboxylase synthetase (HCS). Accordingly, some mutations in HCS cause holocarboxylase deficiency, a rare me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cb59c2429ba1d5d2eebbcd036125e64
https://doi.org/10.1074/jbc.m117.798553
https://doi.org/10.1074/jbc.m117.798553
Publikováno v:
The Journal of biological chemistry. 293(2)
Biotin is an essential cofactor for multiple metabolic reactions catalyzed by carboxylases. Biotin is covalently linked to apoproteins by holocarboxylase synthetase (HCS). Accordingly, some mutations in HCS cause holocarboxylase deficiency, a rare me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6fa791ba8fd4d4fc748b2a72d9fd1a3d
https://pubmed.ncbi.nlm.nih.gov/29158261
https://pubmed.ncbi.nlm.nih.gov/29158261
Publikováno v:
Development. 140:2005-2014
In the one-cell C. elegans embryo, polarity is maintained by mutual antagonism between the anterior cortical proteins PAR-3, PKC-3, PAR-6 and CDC-42, and the posterior cortical proteins PAR-2 and LGL-1 on the posterior cortex. The mechanisms by which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d63e59bbec0f4c2c7eb6af60bc7d25d
https://doi.org/10.1242/dev.088310
https://doi.org/10.1242/dev.088310
Autor:
Kenneth J. Kemphues
Publikováno v:
Genetics. 203(4)
[Figure][1] ![Figure][1] “The relationship between genes and development is unknown.” This is the bold opening statement of the 1980 article by H. Robert Horvitz and John Sulston that reported the first step of a comprehensive genetic analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c31ba5838721ae75bf452915952a4ff
https://pubmed.ncbi.nlm.nih.gov/27516609
https://pubmed.ncbi.nlm.nih.gov/27516609
Publikováno v:
Genetics. 192:929-942
The par genes of Caenorhabditis elegans are essential for establishment and maintenance of early embryo polarity and their homologs in other organisms are crucial polarity regulators in diverse cell types. Forward genetic screens and simple RNAi depl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6857eab8c92da7188377dbc4ab21a582
https://doi.org/10.1534/genetics.112.143727
https://doi.org/10.1534/genetics.112.143727
Publikováno v:
The Journal of Cell Biology
Two actin-assembling formins, CYK-1 and FHOD-1, are important for muscle cell growth and maintenance of the contractile lattice in striated muscle cells.
Muscle contraction depends on interactions between actin and myosin filaments organized int
Muscle contraction depends on interactions between actin and myosin filaments organized int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29e2114009d4f3fed62e4ce54891fdd
http://europepmc.org/articles/PMC3392944
http://europepmc.org/articles/PMC3392944
Publikováno v:
Development. 137:3995-4004
Polarity is essential for generating cell diversity. The one-cell C. elegans embryo serves as a model for studying the establishment and maintenance of polarity. In the early embryo, a myosin II-dependent contraction of the cortical meshwork asymmetr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f767075f689a716e1cc20201bcb282
https://doi.org/10.1242/dev.056028
https://doi.org/10.1242/dev.056028
Publikováno v:
Developmental Biology. 344(2):745-757
Polarity is a fundamental cellular feature that is critical for generating cell diversity and maintaining organ functions during development. In C. elegans, the one-cell embryo is polarized via asymmetric localization of the PAR proteins, which in tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba1fad636be260022618e4f2358a6d52
Publikováno v:
Developmental Biology. 340(1):88-98
PAR-6 is a conserved protein important for establishment and maintenance of cell polarity in a variety of metazoans. PAR-6 proteins function together with PAR-3, aPKC and CDC-42. Mechanistic details of their interactions, however, are not fully under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bddc41b80222064dcf7ccc70d8c24e56