Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kenneth J. Henry"'
Publikováno v:
Chirality. 12:488-495
L-Rhamnal is readily converted into an allyl 2,3-unsaturated-C-glycopyranoside. The (S) configuration of the αL-anomer defines the stereochemical outcome of the future IMDA reaction, leading to the absolute stereochemistry for the trans-decalin moie
Publikováno v:
Tetrahedron Letters. 37:8289-8292
A novel approach to the total synthesis of (±)-ibogamine and (±)-epi-ibogamine, featuring electrophilic substitution at C(2) of N′-CBZ-tryptamine by an allylic acetate, is described.
Autor:
Kenneth J. Henry, Bert Fraser-Reid
Publikováno v:
Tetrahedron Letters. 36:8901-8904
Appropriately protected derivatives of glucal and galactal have been found to undergo efficient Cyclopropanation with ethoxycarbonyl carbene with excellent facial selectivity, while di- O -acetyl-L-rhamnal exhibits lower facial selectivity. The cyclo
Publikováno v:
ChemInform. 23
O-Silylated ketene acetals undergo 1,4 conjugate addition to hindered α,β-unsaturated carbonyl systems at atmospheric pressure in the presence of lithium perchlorate.
Publikováno v:
Tetrahedron Letters. 33:4735-4738
Allylic alcohols of type 1 undergo unprecedented substitution with O-silylated ketene acetals in 3.0 M lithium perchlorate-diethyl ether.
Publikováno v:
Tetrahedron Letters. 33:1817-1820
α-Alkoxy aldehydes undergo chelation controlled addition of allylstannanes with high diastereoselectivity in the presence of 5.0 M lithium perchlorate in diethyl ether at ambient temperature and pressure.
Publikováno v:
Tetrahedron Letters. 32:4665-4668
O-Silylated ketene acetals undergo 1,4 conjugate addition to hindered α,β-unsaturated carbonyl systems at atmospheric pressure in the presence of lithium perchlorate.
Autor:
Paul A. Grieco, Kenneth J. Henry
Publikováno v:
J. Chem. Soc., Chem. Commun.. :510-512
A novel carbon–carbon bond-forming reaction between indole and ββ-disubstituted allylic alcohols in lithium perchlorate–diethyl ether containing a catalytic amount of a Bronsted acid is described; the reaction has been applied to a total synthe
Publikováno v:
J. Chem. Soc., Chem. Commun.. :368-370
The total synthesis of sesbanimide A (1) and B (2) is reported which features (a) the reaction of cyclopentadiene with glyoxylic acid leading to the useful bicyclic lactone building block 3 and (b) the use of 2.5 mol dm–3 lithium perchlorate in die
Autor:
Bert Fraser-Reid, Kenneth J. Henry
Publikováno v:
The Journal of Organic Chemistry. 59:5128-5129
Iodo lactone (6b), derived from D-galactal, undergoes tin hydride medi- ated transannular radical cyclization to give the tricyclic lactone (7), which is easily converted into an advanced precursor of the tricyclic dihydrofuran portion of the potent