Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Kenneth J Gollob"'
Autor:
Amanda Braga Figueiredo, Milton José Barros e Silva, Guilherme Ferreira de Britto Evangelista, Nayane Alves de Lima Galdino, Larissa de Melo Kuil, Iasmim Polido Santos, Kátia Luciano Pereira Morais, Clara Maciel Cavalcanti, Luciana Facure Moredo, João Pedreira Duprat-Neto, Kenneth J Gollob
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e32624- (2024)
The treatment for stage III melanoma has advanced significantly, nevertheless, a substantial proportion of patients experience relapse. Neoadjuvant immune checkpoint blockade has emerged as a promising approach, allowing early micrometastatic disease
Externí odkaz:
https://doaj.org/article/e8156cfed6ac4ff7b8cedd9f63a2d4e5
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 9, p e0010546 (2022)
T cells recognize their ligand, the peptide major histocompatibility complex (MHC), via the T-cell receptor (TCR), which is composed of covalently linked α and β or γ and δ chains. This recognition is critical for T-cell ontogeny and controls the
Externí odkaz:
https://doaj.org/article/c617231246b64477a19230be2cb3522f
Autor:
Luísa M D Magalhães, Agostinho Viana, Augusto C de Jesus, Egler Chiari, Lúcia Galvão, Juliana A Gomes, Kenneth J Gollob, Walderez O Dutra
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188083 (2017)
Neutrophils are critical players in the first line of defense against pathogens and in the activation of subsequent cellular responses. We aimed to determine the effects of the interaction of Trypanosoma cruzi with human neutrophils, using isolates o
Externí odkaz:
https://doaj.org/article/0a65bd0aefbc414c838066f208edfe26
Autor:
Walderez Ornelas Dutra, Cristiane Alves Silva Menezes, Fernanda Nobre Amaral Villani, Germano Carneiro da Costa, Alexandre Barcelos Morais da Silveira, Débora d'Ávila Reis, Kenneth J Gollob
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 104, Pp 208-218 (2009)
Perhaps one of the most intriguing aspects of human Chagas disease is the complex network of events that underlie the generation of protective versus pathogenic immune responses during the chronic phase of the disease. While most individuals do not d
Externí odkaz:
https://doaj.org/article/ea8edf37b9d54150b6a229a6b2021d80
Differential Activation of Human Monocytes and Lymphocytes by Distinct Strains of Trypanosoma cruzi.
Autor:
Luísa M D Magalhães, Agostinho Viana, Egler Chiari, Lúcia M C Galvão, Kenneth J Gollob, Walderez O Dutra
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 7, p e0003816 (2015)
BACKGROUND:Trypanosoma cruzi strains are currently classified into six discrete typing units (DTUs) named TcI to VI. It is known that these DTUs have different geographical distribution, as well as biological features. TcI and TcII are major DTUs fou
Externí odkaz:
https://doaj.org/article/a689f789a2544cedaefce8d064559c6f
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 7, p e3010 (2014)
Chagas disease is caused by infection with the protozoan Trypanosoma cruzi, and although over 100 years have passed since the discovery of Chagas disease, it still presents an increasing problem for global public health. A plethora of information con
Externí odkaz:
https://doaj.org/article/8d2fd4533aeb44479429b7a4e3208d2f
Autor:
Ananda D. Lopes, Nayane A. L. Galdino, Amanda B. Figueiredo, Rafael C. Brianese, Katia L. P. Morais, Marina De Brot, Cynthia A. B. T. Osório, Andrea Teixeira‐Carvalho, Vinicius F. Calsavara, Guilherme F. B. Evangelista, Natalia S. Alves, Fabiana B. Makdissi, Solange M. Sanches, Vladmir C. Cordeiro de Lima, Dirce M. Carraro, Kenneth J. Gollob
Publikováno v:
Immunology. 169:229-241
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3103667e0faecc6513255f7cab7ec663
https://doi.org/10.1111/imm.13627
https://doi.org/10.1111/imm.13627
Autor:
Carolina Cattoni Koh, Amanda B. Wardini, Millene Vieira, Livia S. A. Passos, Patrícia Massara Martinelli, Eula Graciele A. Neves, Lis Riberido do Vale Antonelli, Daniela Faria Barbosa, Teresiama Velikkakam, Eduardo Gutseit, Gustavo B. Menezes, Rodolfo Cordeiro Giunchetti, Paulo Roberto Lima Machado, Edgar M. Carvalho, Kenneth J. Gollob, Walderez Ornelas Dutra
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Cell death plays a fundamental role in mounting protective and pathogenic immunity. Etosis is a cell death mechanism defined by the release of extracellular traps (ETs), which can foster inflammation and exert microbicidal activity. While etosis is o
Externí odkaz:
https://doaj.org/article/f92820194e8d461db371ad3358949493
Publikováno v:
The Lancet Microbe. 3:e711-e722
The complexity of host-pathogen interactions often leads to distinct clinical outcomes upon infection with different pathogen strains. In this Review, we explore the interactions between the highly diverse Trypanosoma cruzi population and the human h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83be0be3d8c38275e2bd96a859f45c5a
https://doi.org/10.1016/s2666-5247(21)00265-2
https://doi.org/10.1016/s2666-5247(21)00265-2
Publikováno v:
Immunology. 165:371-385
Double-negative (DN) T cells are present at relatively low frequencies in human peripheral blood, and are characterized as expressing the alpha-beta or gamma-delta T-cell receptor (TCR), but not the CD4 nor the CD8 co-receptors. Despite their low fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b4a586b736c63e98f15fb2f8ac8d221
https://doi.org/10.1111/imm.13441
https://doi.org/10.1111/imm.13441