Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kenneth J Coker"'
Autor:
Erin A Bassett, Nicholas Tokarew, Ema A Allemano, Chantal Mazerolle, Katy Morin, Alan J Mears, Brian McNeill, Randy Ringuette, Charles Campbell, Sheila Smiley, Neno T Pokrajac, Adrian M Dubuc, Vijay Ramaswamy, Paul A Northcott, Marc Remke, Philippe P Monnier, David Potter, Kim Paes, Laura L Kirkpatrick, Kenneth J Coker, Dennis S Rice, Carol Perez-Iratxeta, Michael D Taylor, Valerie A Wallace
Publikováno v:
eLife, Vol 5 (2016)
The tumor microenvironment is a critical modulator of carcinogenesis; however, in many tumor types, the influence of the stroma during preneoplastic stages is unknown. Here we explored the relationship between pre-tumor cells and their surrounding st
Externí odkaz:
https://doaj.org/article/df33c3a6740f407fabdea0d8d14a2d4f
Autor:
Kim Paes, David Potter, Neno T Pokrajac, Valerie A. Wallace, Paul A. Northcott, Charles Campbell, Katy Morin, Sheila Smiley, Laura L. Kirkpatrick, Brian McNeill, Randy Ringuette, Philippe P. Monnier, Nicholas Tokarew, Ema A Allemano, Chantal Mazerolle, Dennis S. Rice, Kenneth J Coker, Adrian M. Dubuc, Alan J. Mears, Michael D. Taylor, Marc Remke, Carol Perez-Iratxeta, Erin A. Bassett, Vijay Ramaswamy
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
The tumor microenvironment is a critical modulator of carcinogenesis; however, in many tumor types, the influence of the stroma during preneoplastic stages is unknown. Here we explored the relationship between pre-tumor cells and their surrounding st
Autor:
Marc Remke, Brian McNeill, Valerie A. Wallace, Neno T Pokrajac, Kenneth J Coker, Dennis S. Rice, Carol Perez-Iratxeta, Kim Paes, David Potter, Nicholas Tokarew, Katy Morin, Laura L. Kirkpatrick, Philippe P. Monnier, Michael D. Taylor, Charles Campbell, Adrian M. Dubuc, Alan J. Mears, Sheila Smiley, Chantal Mazerolle, Ema A Allemano, Paul A. Northcott, Vijay Ramaswamy, Randy Ringuette, Erin A. Bassett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d902be3b5907adda02b836521e679959
https://doi.org/10.7554/elife.16764.032
https://doi.org/10.7554/elife.16764.032
Autor:
Chunmei Yang, Silvia Mora, Jason K. Kim, Baoli Yang, Debbie C. Thurmond, Roger A. Williamson, Jeffrey E. Pessin, Kenneth J. Coker, Ann C. Davis, Gerald I. Shulman
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Universidad de Barcelona
To investigate the physiological function of syntaxin 4 in the regulation of GLUT4 vesicle trafficking, we used homologous recombination to generate syntaxin 4-knockout mice. Homozygotic disruption of the syntaxin 4 gene results in early embryonic le
Autor:
Jing Min, Yoichi Noda, Brian P. Ceresa, Li Jyun Syu, Makoto Kanzaki, Jeffrey E. Pessin, Alan R. Saltiel, Jeffrey S. Elmendorf, Kenneth J. Coker, Shuichi Okada
Publikováno v:
Molecular Cell. 3(6):751-760
Insulin-stimulated glucose transport and GLUT4 translocation require regulated interactions between the v-SNARE, VAMP2, and the t-SNARE, syntaxin 4. We have isolated a novel syntaxin 4–binding protein, Synip, which specifically interacts with synta
Publikováno v:
Journal of Biological Chemistry. 274:2593-2596
Autor:
Kathleen H. Holt, Anne V. Philips, Robert Brommage, Brian Zambrowicz, William J. Paradee, Gwenn M. Hansen, Arthur T. Sands, Christopher M. DaCosta, Adisak Suwanichkul, Deon D. Smith, Derek E. Eberhart, Urvi Desai, David R. Powell, Jean Pierre Revelli, Laura L. Kirkpatrick, Kenneth A. Platt, Kenneth J Coker, Gregory K. Fontenot, Michael R. Kelly, Michael S. Donoviel, Dorit B. Donoviel
Publikováno v:
Obesity (Silver Spring, Md.). 16(10)
We developed a high-throughput approach to knockout (KO) and phenotype mouse orthologs of the 5,000 potential drug targets in the human genome. As part of the phenotypic screen, dual-energy X-ray absorptiometry (DXA) technology estimates body-fat sto
Autor:
Amanda Wyman, Maggie M.-Y. Chi, Joan K. Riley, Mary O. Carayannopoulos, Chunmei Yang, Jeffrey E. Pessin, Kelle H. Moley, Kenneth J. Coker
Publikováno v:
Molecular endocrinology (Baltimore, Md.). 17(10)
Target-soluble N-ethylmaleimide-sensitive factor attachment protein receptors (t-SNAREs) are receptors that facilitate vesicle and target membrane fusion. Syntaxin 4 is the t-SNARE critical for insulin-stimulated glucose transporter 4 (GLUT4)-plasma
Publikováno v:
Experimental cell research. 268(2)
Two residues have been shown to be critical for the kinase activity of the receptor for epidermal growth factor (EGF): lysine-721, which functions in the binding of ATP by correctly positioning the γ-phosphate for phosphoryl transfer, and aspartate-
Autor:
Jeffrey W. Ryder, Jeffrey E. Pessin, Chunmei Yang, Kenneth J. Coker, Polly A. Hansen, Silvia Mora, Lee-Ann H. Allen
To investigate the physiological function of the VAMP3 vesicle SNARE (v-SNARE) isoform in the regulation of GLUT4 vesicle trafficking, we generated homozygotic VAMP3 null mice by targeted gene disruption. The VAMP3 null mice had typical growth rate a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ae57da47825e7017fadf201134e54a
https://europepmc.org/articles/PMC86703/
https://europepmc.org/articles/PMC86703/