Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Kenneth I. Strauss"'
Autor:
Robert A. Casero, Francis Huttinger, Kenneth I. Strauss, Kamyar Zahedi, Tracy Murray-Stewart, Ryan Morrison
Publikováno v:
Journal of Neurotrauma. 27:515-525
Polyamines spermine and spermidine are highly regulated, ubiquitous aliphatic cations that maintain DNA structure and function as immunomodulators and as antioxidants. Polyamine homeostasis is disrupted after brain injuries, with concomitant generati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590bca8230b5e56284d37439b5750246
https://doi.org/10.1089/neu.2009.1097
https://doi.org/10.1089/neu.2009.1097
Autor:
Patrick Sullivan, David B. Pettigrew, Keith A. Crutcher, Kenneth I. Strauss, Shirley B. Shelton, Weidong Zhou, Alison Hermann
Publikováno v:
Journal of Neuroscience Methods. 168:431-442
A refined battery of neurological tests, SNAP (Simple Neuroassessment of Asymmetric Impairment), was developed and validated to efficiently assess neurological deficits induced in a mouse model of traumatic brain injury. Four to 7-month old mice were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3865a63e6072f9d7a5a5347576c51dc
https://doi.org/10.1016/j.jneumeth.2007.11.003
https://doi.org/10.1016/j.jneumeth.2007.11.003
Autor:
Kenneth I. Strauss, Susan A. Jansen, Elise Murphy, Luella J. Rossi, Michael R. Borenstein, Hongfei Yue, Mary F. Barbe
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 43:1122-1134
A sensitive, specific, and robust liquid chromatography/mass spectrometric (LC/MS) method was developed and validated that allows simultaneous analysis of arachidonic acid (AA) and its cyclooxygenase, cytochrome P450, and lipoxygenase pathway metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f25753ee677893ead979ecdad8e4ed9c
https://doi.org/10.1016/j.jpba.2006.10.009
https://doi.org/10.1016/j.jpba.2006.10.009
Autor:
Daming Zhu, Krishna Banaudha, Robert H. Lipsky, Zehra Qureshi, Ann M. Marini, Antonello Novelli, Xuan Wu, Artin Terhakopian, Kenneth I. Strauss
Publikováno v:
Journal of Neuroscience Research. 80:104-113
N-Methyl-d-aspartate (NMDA) at a subtoxic concentration (100 μM) promotes neuronal survival against glutamate-mediated excitotoxicity via a brain-derived neurotrophic factor (BDNF) autocrine loop in cultured cerebellar granule cells. The signal tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b5dc4e5373e38fd4d95a55a3d13642
https://doi.org/10.1002/jnr.20422
https://doi.org/10.1002/jnr.20422
Autor:
Aryn Schloemer, Kevin A. Burns, Frank R. Sharp, Michael T. Williams, Pasko Rakic, Richard A. Flavell, Charles V. Vorhees, Wei Lan Weng, Chia-Yi Kuan, Aigang Lu, Roger I. Davis, Kenneth I. Strauss
Publikováno v:
The Journal of Neuroscience. 24:10763-10772
Recent studies suggest that postmitotic neurons can reenter the cell cycle as a prelude to apoptosis after brain injury. However, most dying neurons do not pass the G1/S-phase checkpoint to resume DNA synthesis. The specific factors that trigger abor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c98b4b317a5e1726dffb34cb3f5442f
https://doi.org/10.1523/jneurosci.3883-04.2004
https://doi.org/10.1523/jneurosci.3883-04.2004
Autor:
Mary F. Barbe, Kenneth I. Strauss, Michael R. Borenstein, Hongfei Yue, Susan A. Jansen, Luella J. Rossi
Publikováno v:
Journal of Chromatography B. 803:267-277
Arachidonic acid (AA) is metabolized to prostaglandins (PGs) via cyclooxygenases (COX) catalysis, and to epoxyeicosatrienoic acids (EETs), dihydroxyeicosatrienoic acids (DiHETrEs), and hydroxyeicosatetraenoic acids (HETEs) via cytochrome P450 (CYP450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d311455234b980a7356441ac2111104
https://doi.org/10.1016/j.jchromb.2003.12.027
https://doi.org/10.1016/j.jchromb.2003.12.027
Publikováno v:
Neurotoxicity Research. 6:333-342
Cell death/survival following traumatic brain injury (TBI) may be a result of alterations in the intracellular ratio of death and survival factors. Bcl-2 family genes mediate both cell survival and the initiation of cell death. Using lysate RNase pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c46bef595347553fe4e97e31c29190
https://doi.org/10.1007/bf03033444
https://doi.org/10.1007/bf03033444
Autor:
Yang Tang, Aigang Lu, Ruiqiong Ran, Todd F. Glass, Frank R. Sharp, Kenneth I. Strauss, Myriam Bernaudin, Tim Ardizzone
Publikováno v:
NeuroRX. 1:26-35
Animals exposed to brief periods of moderate hypoxia (8% to 10% oxygen for 3 hours) are protected against cerebral and cardiac ischemia between 1 and 2 days later. This hypoxia preconditioning requires new RNA and protein synthesis. The mechanism of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3210eb9ea558f0fcfca53da1521b548e
https://doi.org/10.1602/neurorx.1.1.26
https://doi.org/10.1602/neurorx.1.1.26
Autor:
Kenneth I. Strauss, Laura L. Pashko, Russell W. Cole, Arthur G. Schwartz, Raj K. Narayan, Amir S. Malik, Woodrow W. Wendling
Publikováno v:
Journal of Neurotrauma. 20:463-476
The purpose of this study was to investigate the efficacy of a novel steroid, fluasterone (DHEF, a dehydroepiandrosterone (DHEA) analog), at improving functional recovery in a rat model of traumatic brain injury (TBI). The lateral cortical impact mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d88ee8fe3bd6d504f3c5b099cb8714
https://doi.org/10.1089/089771503765355531
https://doi.org/10.1089/089771503765355531
Autor:
Daming Zhu, Karen M. Mearow, Robert H. Lipsky, Peter Okagaki, Krishna Banaudha, Ann M. Marini, Kenneth I. Strauss, Xuan Wu, Xueying Jiang
Publikováno v:
Annals of the New York Academy of Sciences. 993:134-145
Delineating the mechanisms of survival pathways that exist in neurons will provide important insight into how neurons utilize intracellular proteins as neuroprotectants against the causes of acute neurodegeneration. We have employed cultured rat cere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a4d1f79344ae58fae192f1391b73585
https://doi.org/10.1111/j.1749-6632.2003.tb07522.x
https://doi.org/10.1111/j.1749-6632.2003.tb07522.x